Lymphoblastic Lymphoma (DBCOND0032667)

Identifiers

Synonyms
Lymphoma, Lymphoblastic / Lymphoblastic lymphoma / Lymphoblastic (diffuse) lymphoma / Precursor cell lymphoblastic lymphoma (disorder) / Malignant lymphoma - small cleaved cell (disorder) / Precursor cell lymphoblastic lymphoma (morphologic abnormality) / Precursor cell lymphoblastic leukemia (morphologic abnormality) / Precursor Cell Lymphoblastic Leukemia-Lymphoma / Non-Hodgkin lymphoma, unspecified / Mantle cell lymphoma / Non-Hodgkin lymphoma (morphologic abnormality) / Non-Hodgkin's lymphoma / Non-Hodgkin's lymphoma NOS / Lymphoma, Non-Hodgkin / Non-Hodgkin's lymphoma (disorder) / Lymphoma (non-Hodgkin's)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Asparaginase Erwinia chrysanthemi
An asparagine-specific enzyme used as part of a chemotherapeutic regimen to treat patients with acute lymphoblastic leukemia and lymphoblastic lymphoma.
No drug targets
Mercaptopurine
An antineoplastic agent used to treat acute lymphocytic leukemia.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT00199030
Treatment of Relapsed T-cell Acute Lymphoblastic Leukemia or T-lymphoblastic Lymphoma With MabCampathtreatment2completed
NCT02396043
Modified BFM-95 Regimen as First-Line Chemotherapy in Adults With T- Lymphoblastic Lymphomatreatment2recruiting
NCT00186875
Therapy for Pediatric Relapsed or Refractory Acute Lymphoblastic Leukemiatreatment2completed
NCT00199017
German Multicenter Trial for the Treatment of Newly Diagnosed T-lymphoblastic Lymphoma in Adultstreatment4completed
NCT06533748
Therapy for Newly Diagnosed Patients With B-Cell Precursor Acute Lymphoblastic Leukemia and Lymphomatreatment2not_yet_recruiting
NCT02881086
Optimization of Therapy in Adult Patients with Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma by Individualised, Targeted and Intensified Treatmenttreatment3active_not_recruiting
NCT06289673
Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphomatreatment4not_yet_recruiting
NCT05602194
Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphomasupportive_care3recruiting
NCT06207123
A Study to Investigate LP-118, Ponatinib, Vincristine and Dexamethasone in Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LBL)treatment1 / 2recruiting
NCT06514794
A Phase 2 Study of WU-CART-007, an Anti-CD7 Allogeneic CAR-T Cell Therapy inT-Cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphomatreatment2not_yet_recruiting
NCT02257684
A Dose Confirmation and Pharmacokinetic Study of Pegcrisantaspase Administered as Intravenous (IV) Infusion in Children and Young Adults With Acute Lymphoblastic Leukemia (ALL) /Lymphoblastic Lymphoma (LBL). Following Hypersensitivity to Pegaspargase (Oncaspar)treatment2terminated
NCT04195633
Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignanciestreatment2recruiting
NCT03571997
Study of Prognostic Factors in Adult Lymphoblastic LymphomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT01614197
A Trial of Temsirolimus With Etoposide and Cyclophosphamide in Children With Relapsed Acute Lymphoblastic Leukemia and Non-Hodgkins Lymphomatreatment1completed
NCT01363128
Combination Chemotherapy and Ofatumumab in Treating Patients With Acute Lymphoblastic Leukemia or Lymphoblastic Lymphomatreatment2completed
NCT00719888
Umbilical Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With Hematologic Diseasetreatment2active_not_recruiting
NCT04984356
A Phase 1/2 Study of the Safety and Efficacy of Anti-CD7 Allogeneic CAR-T Cells (WU-CART-007) in Patients With Relapsed or Refractory T-ALL/LBLtreatment1 / 2completed
NCT01451515
NHL16: Study For Newly Diagnosed Patients With Acute Lymphoblastic Lymphomatreatment2completed
NCT02290132
ATG Could Improve the Outcome Of Hematopoietic Stem Cell Transplant in Patients With Highly Aggressive T Cell TumorsNot AvailableNot Availableunknown_status
NCT01790152
Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer TreatmentNo drug interventionsNot AvailableNot Availablerecruiting
NCT05476770
Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignanciestreatment1recruiting
NCT00866749
Augmented Berlin-Frankfurt-Munster (BFM) Therapy for Adolescent/Young Adults With Acute Lymphoblastic Leukemia or Acute Lymphoblastic Lymphomatreatment2completed
NCT00949741
Observational Study for the Cytofluorimetric Analysis of Cerebrospinal Fluid in Non-Hodgkin's Lymphoma PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT03178617
High-Intensity Parent Intervention Program in Improving Learning and School Functioning in Latino Children With Acute Leukemia or Lymphoblastic LymphomaNo drug interventionssupportive_careNot Availableactive_not_recruiting
NCT02661035
Allo HSCT Using RIC for Hematological Diseasestreatment2completed
NCT04942730
Benadamustine, Fludarabine and Busulfan Conditioning in Recipients of Haploidentical Stem Cell Transplantation (FluBuBe)treatment2completed
NCT03314974
Myeloablative Allo HSCT With Related or Unrelated Donor for Heme DisordersNo drug interventionstreatment2recruiting
NCT02845882
LBL-2016 for Children or Adolescents in Chinatreatment3active_not_recruiting
NCT01761682
Acute Lymphoblastic Leukemia Registry at Asan Medical CenterNo drug interventionsNot AvailableNot Availableterminated
NCT00199082
Newly Diagnosed Mature B-ALL, Burkitt's Lymphoma and Other High-grade Lymphoma in Adultstreatment4completed
NCT01177527
Questionnaire and Tissue Banking For Multiple Myeloma, Waldenstrom Macroglobulinemia and Related DisordersNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT03592576
Expanded Access to NavitoclaxNot AvailableNot Availableno_longer_available
NCT02912676
Thiopurine EnhAnced Maintenance Therapytreatment1 / 2completed
NCT05428176
A High Intensity Electronic Health Intervention for the Reduction of Learning Disparities in Childhood Cancer SurvivorsNo drug interventionssupportive_careNot Availablerecruiting
NCT05794880
MCW Alpha/Beta T-Cell and B-Cell Depletion With Targeted ATG DosingNo drug interventionstreatmentNot Availablerecruiting
NCT01163201
T-Regulatory Cell and CD3 Depleted Double Umbilical Cord Blood Transplantation in Hematologic Malignanciestreatment1 / 2withdrawn
NCT02228772
Phase I Study of MLN 9708 in Addition to Chemotherapy for the Treatment of Acute Lymphoblastic Leukemia in Older Adultstreatment1completed
NCT06527781
A Study of PD5K3 in Healthy Adult Volunteerstreatment1completed
NCT01643408
A Study of Erwinaze Administered Intravenously in Patients Who Had an Allergy to Frontline Asparaginase Therapytreatment2completed
NCT00412243
Clofarabine and Cyclophosphamide Combination in Acute Lymphoblastic Leukemia Patientstreatment1 / 2completed
NCT01513603
Trial of Cladribine, Cytarabine, Mitoxantrone, Filgrastim (CLAG-M) in Relapsed Acute Lymphoblastic Leukemiatreatment2unknown_status
NCT05885464
A Study Evaluating the Safety and Efficacy of BEAM-201 in Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia (T-ALL) or T-Cell Lymphoblastic Lymphoma (T-LL)No drug interventionstreatment1 / 2recruiting
NCT02506933
Multi-antigen CMV-MVA Triplex Vaccine in Reducing CMV Complications in Patients Previously Infected With CMV and Undergoing Donor Hematopoietic Cell Transplantsupportive_care2active_not_recruiting
NCT00587054
Trial of Allogeneic Stem Cell Transplants From HLA Compatible, Related and Unrelated Donors After a Myeloablative Preparative Regimen With Hyperfractionated TBI, Thiotepa and Fludarabine For Adult Patients With Lymphohematopoietic DisordersNo drug interventionstreatment2completed
NCT04060277
Triplex Vaccine in Preventing CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplantationsupportive_care2active_not_recruiting
NCT01910428
L-asparaginase Encapsulated in Red Blood Cells (Eryaspase) for Treatment of Adult Patients With ALL or LBLtreatment1terminated
NCT00882011
Observational Controlled Clinical Trials, on Adult Patients With T-lymphoblastic Lymphoma Treated With Intensive Chemo/Radiotherapy or Intensive Chemotherapy Followed by Transplant. Evaluation of Clinical, Anatomy -Pathological ParametersNo drug interventionsNot AvailableNot Availableunknown_status
NCT00195871
Safety and Efficacy of an Adult Acute Lymphoblastic Leukemia Chemotherapy for Adult Lymphoblastic Lymphomatreatment2unknown_status
NCT03792256
Palbociclib in Combination With Chemotherapy in Treating Children With Relapsed Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LL)treatment1active_not_recruiting
NCT01184885
A Pilot Study to Determine the Safety and Tolerability of Sirolimus Given With Hyper-CVAD Chemotherapytreatment0completed
NCT02220985
Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHDtreatment2active_not_recruiting
NCT04943952
JZP458 - Recombinant Erwinia Asparaginase for Treatment of ALL / LBL Patients With Hypersensitivity to E. Coli-derived AsparaginaseNot AvailableNot Availableapproved_for_marketing
NCT06508099
Vitamin A and D Supplementation in Allogeneic HCTtreatment2recruiting
NCT02535806
Four Drug Reinduction With Bortezomib for Relapsed or Refractory ALL or LL in Children and Young Adultstreatment2terminated
NCT06477549
BeFluBu vs FluBuRux Conditioning in Haploidentical HCTtreatment2recruiting
NCT01962636
Umbilical Cord Blood Transplantation Using a Myeloablative Preparative Regimen for Hematological DiseasestreatmentNot Availablerecruiting
NCT02938741
ATG Based Conditioning Regimen in HLA Related HSCT for Aggressive T-cell Tumorstreatment4unknown_status
NCT01619124
Osteonecroses in Pediatric Patients With ALLNo drug interventionsNot AvailableNot Availableunknown_status
NCT03810196
CD45RA Depleted Peripheral Stem Cell Addback for Viral or Fungal Infections Post TCRαβ/CD19 Depleted HSCTNo drug interventionstreatmentNot Availablerecruiting
NCT01100658
Effects of Methylphenidate on Attention Deficits in Childhood Cancer SurvivorstreatmentNot Availableterminated
NCT00187122
Treatment for Patients With Stage III or IV Non-Hodgkin LymphomatreatmentNot Availablecompleted
NCT04666025
SARS-CoV-2 Donor-Recipient Immunity TransferNo drug interventionsNot AvailableNot Availablecompleted
NCT03181126
A Study of Venetoclax in Combination With Navitoclax and Chemotherapy in Subjects With Relapsed/Refractory Acute Lymphoblastic Leukemia or Relapsed/Refractory Lymphoblastic Lymphomatreatment1completed
NCT01574274
SC-PEG Asparaginase vs. Oncaspar in Pediatric Acute Lymphoblastic Leukemia (ALL) and Lymphoblastic Lymphomatreatment2active_not_recruiting
NCT01943682
Safety Study of CPX-351 in Children With Relapsed Leukemia or LymphomaNo drug interventionstreatment1completed
NCT01813344
Hyper-CVAD Treatment in Lymphoblastic LymphomaNo drug interventionsNot AvailableNot Availableunknown_status
NCT03564704
Precision Diagnosis Directing HDACi Chidamide Target Therapy for Adult T-LBL/ALLtreatment2 / 3unknown_status
NCT03328104
Everolimus in Combination With Nelarabine, Cyclophosphamide and Etoposide in Lymphoblastic Leukemia/Lymphomatreatment1completed
NCT01842672
Mitoxantrone and Clofarabine for Treatment of Recurrent NHL or Acute Leukemiatreatment1 / 2completed
NCT02419469
Augmented Berlin-Frankfurt-Munster Therapy Plus Ofatumumab for Young Adults With Acute Lymphoblastic Leukemia or Lymphoblastic Lymphomatreatment2terminated
NCT02960646
Engineered Donor Stem Cell Transplant in Treating Patients With Hematologic Malignanciestreatment1completed
NCT03023046
Etoposide, Prednisone, Vincristine Sulfate, Cyclophosphamide, and Doxorubicin in Treating Patients With Acute Lymphoblastic Leukemia or Lymphoblastic Lymphomatreatment2completed
NCT01474681
Safety and Tolerability of HSC835 in Patients With Hematological Malignanciestreatment1 / 2completed