Metastatic Prostate Cancer (DBCOND0033188)

Identifiers

Synonyms
Prostate Cancer Metastatic Disease / Prostate Cancer Metastatic / Metastatic prostate cancer / Carcinoma of the prostate metastatic / Prostatic cancer metastatic

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Estramustine
An antineoplastic agent used for the management of metastatic and/or progressive prostate cancer in palliative setting.
Fluorocholine F-18
A radiopharmaceutical indicated in PET scans of the prostate.
No drug targets
Gallium Ga-68 gozetotide
A radiopharmaceutical agent used in the diagnosis of prostate-specific membrane antigen (PSMA) positive lesions in male patients during positron emission tomography.
Nilutamide
An antineoplastic hormone used to treat prostate cancer.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT01155791
Phase I Sodium Selenite in Combination With Docetaxel in Castration-resistant Prostate Cancertreatment1terminated
NCT04262154
Study of Abiraterone Acetate or Enzalutamide, Atezolizumab, GnRH Analog and Radiation Therapy in Men With Newly Diagnosed Hormone-sensitive Prostate Cancertreatment2active_not_recruiting
NCT03763851
Cannabis Oil and Radiation Therapy for the Management of PainNo drug interventionstreatment2terminated
NCT04556045
Exercise Therapy and Radiation Therapy (EXERT) for Metastatic Prostate CancerNo drug interventionssupportive_careNot Availablerecruiting
NCT01303705
Anti-OX40, Cyclophosphamide (CTX) and Radiation in Patients With Progressive Metastatic Prostate Cancertreatment1completed
NCT04220983
PRAGMA (Prostate Radio Ablation Guided by Magnetic Resonance Imaging Acquisition) in Metastatic Prostate CancerNo drug interventionstreatmentNot Availablecompleted
NCT05896371
A Phase 1/2 Study of Personalized PSMA Radiopharmaceutical Therapytreatment1 / 2not_yet_recruiting
NCT04846478
Phase Ia/Ib Talazoparib + Tazemetostat for mCRPCtreatment1active_not_recruiting
NCT03110588
Phase I Trial of PACE for Metastatic Prostate Cancertreatment1withdrawn
NCT05885009
Feasibility and Impact of Liquid Biopsy Genomic Profiling on Treatment Patients With Metastatic Prostate Cancer in Spain (SOLTI-2102)No drug interventionsNot AvailableNot Availablerecruiting
NCT04400656
PROState Pathway Embedded Comparative TrialNo drug interventionsNot AvailableNot Availablecompleted
NCT06177015
Intermittent Darolutamide Treatment in the Triple Therapy of mHSPCtreatment3recruiting
NCT01815515
Evaluation of 18F-DCFBC PSMA-based PET Imaging for Detection of Metastatic Prostate Cancerdiagnostic1 / 2completed
NCT02655952
Dose Escalating Study of Foxy-5 in Breast-, Colon- or Prostate Cancer Patientstreatment1completed
NCT04746300
imPlementing ROutine Molecular Characterization in Patients With Metastatic Castration Resistant ProstaTe Cancer by NGSNo drug interventionsNot AvailableNot Availablerecruiting
NCT05167175
The Study of Olaparib Combined With Abiraterone and Prednisone in mHSPC Patients With HRR Gene Mutationtreatment2recruiting
NCT00439270
Study of Dasatinib and Docetaxel in Metastatic Hormone Refractory Prostate Cancertreatment1 / 2completed
NCT06009549
A Journey Into Participation Patterns Among Metastatic Prostate Cancer PatientsNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT03432949
Radium-223 Combined With Dexamethasone as First-line Therapy in Patients With M+CRPCtreatment4active_not_recruiting
NCT01957436
A Phase III Study for Patients With Metastatic Hormone-naïve Prostate Cancertreatment3active_not_recruiting
NCT06303713
LuCarbo - a Study of 177Lu-PSMA-617 Plus Carboplatin in Metastatic Castrate-resistant Prostate Cancertreatment1recruiting
NCT05751941
Study of Sipuleucel-T With or Without Continuing New Hormonal Agents in Metastatic Prostate Cancertreatment2recruiting
NCT01012141
Docetaxel With a Phytochemical in Treating Patients With Hormone Independent Metastatic Prostate Cancertreatment2completed
NCT03554317
COMbination of Bipolar Androgen Therapy and Nivolumabtreatment2completed
NCT02206724
Prospective Evaluation of Stereotactic Body Radiotherapy for Metastatic Prostate CancerNo drug interventionstreatmentNot Availablewithdrawn
NCT04330716
Genetic Testing for Breast, Ovarian, Pancreatic, and Prostate CancersNo drug interventionshealth_services_researchNot Availablecompleted
NCT05404139
Duration of Enzalutamide and ADT With Metastasis Directed Therapy in Oligometastatic Cancer of the Prostate (DIRECT)treatment2active_not_recruiting
NCT06050239
Study of 177Lu-PSMA-0057 in Metastatic Prostate Cancertreatment0recruiting
NCT01981122
A Study of Sipuleucel-T With Administration of Enzalutamide in Men With Metastatic Castrate-Resistant Prostate Cancerbasic_science2completed
NCT06040125
Debunking the Frailty-sarcopenIa-ADT Axis in mEtastatic Prostate canceR With multiComponent Exercise: The FIERCE TrialNo drug interventionssupportive_careNot Availablerecruiting
NCT06350825
Cytoreductive Prostatectomy Combined With Triple or Dual Systemic Therapy in mHSPC PatientsNo drug interventionstreatment3recruiting
NCT04026230
Impact of Atorvastatin on Prostate Cancer Progression During ADTtreatment3recruiting
NCT04925648
Psma Intensity Can be Altered by Androgen and Phospho-SrC Obstructiontreatment2recruiting
NCT04140526
Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLCtreatment1 / 2recruiting
NCT04086966
PSMA-PET/MRI for Radiation Treatment Planning in Patients With Locally Metastatic Prostate Cancer: A Pilot StudyNo drug interventionsdiagnostic1completed
NCT03050866
Cabazitaxel in mCRPC Patients With AR-V7 Positive Circulating Tumor Cells (CTCs)diagnostic2unknown_status
NCT05800665
A Study Evaluating the Safety, Pharmacokinetics, and Activity of RO7656594 In Participants With Advanced or Metastatic Prostate CancerNo drug interventionstreatment1recruiting
NCT05717582
Maximal Cytoreductive Therapies on Post-treatment Metastases in Pts With mHSPC During Apalutamide Plus ADT Treatmenttreatment2not_yet_recruiting
NCT03073473
Evaluation of the NantHealth GPS Cancer Test in Patients With Advanced CancersNo drug interventionsNot AvailableNot Availableterminated
NCT05471427
Predictive fActors for toleraNce to Taxane Based CHemotherapy In Older adultS Affected by mEtastatic Prostate CancerNot AvailableNot Availablecompleted
NCT02151760
Study of 18F-DCFPyL, a Second Generation Low-molecular Weight PSMA-based PET Radiotracer, in Patients With Prostate Cancerdiagnostic1completed
NCT02036060
Abiraterone Acetate in Combination With Docetaxel After Disease Progression to Abiraterone Acetate in Metastatic Castration Resistant Prostate Cancer.treatment2completed
NCT04085991
Two TraCer PositROn EmiSSion Tomography ComBination for Efficacy EstimatiOn of Prostate Specific Membrane Antigen Radioligand Therapy in Patients With Metastatic Prostate CancerNo drug interventionstreatment2terminated
NCT06267729
Study of AZD0754 in Participants With Metastatic Prostate CancerNo drug interventionstreatment1 / 2recruiting
NCT06566989
A Study of the Absorption, Distribution, Metabolism, and Elimination of Opevesostat (MK-5684) in Healthy Adult Male Participants (MK-5684-008)treatment1not_yet_recruiting
NCT05367440
Study of AZD5305 When Given in Combination With New Hormonal Agents in Patients With Metastatic Prostate Cancertreatment1 / 2recruiting
NCT03764540
Docetaxel Versus Cabazitaxel Post Abiraterone or Enzalutamidetreatment2active_not_recruiting
NCT03181867
18F-DCFPyL PET/CT in High Risk and Recurrent Prostate Cancerdiagnostic2enrolling_by_invitation
NCT05156372
Adjuvant High-intensity Interval Training During Chemotherapy in Metastatic Prostate Cancer PatientsNo drug interventionstreatmentNot Availablewithdrawn
NCT06516510
A Dosimetry Study of Lutetium (177Lu) rhPSMA-10.1 and Lutetium (177Lu) Vipivotide Tetraxetan (Pluvicto®) in Patients With Non-curative Metastatic Prostate Cancerother0not_yet_recruiting
NCT02963155
Study of Natural Killer Cells in Patients With Metastatic Prostate Cancer: Relationship With Survival and Response Time to CastrationNo drug interventionsbasic_scienceNot Availableunknown_status
NCT04926155
The Effect of Metformin in Patients With Metastatic Castration-resistant Prostate Cancertreatment2unknown_status
NCT01560923
Phase II Study of Sipuleucel-T and Indoximod for Patients With Refractory Metastatic Prostate Cancertreatment2completed
NCT02730338
INTense ExeRcise for surviVAL Among Men With Metastatic Prostate Cancer (INTERVAL - GAP4)No drug interventionstreatmentNot Availableactive_not_recruiting
NCT03072238
Ipatasertib Plus Abiraterone Plus Prednisone/Prednisolone, Relative to Placebo Plus Abiraterone Plus Prednisone/Prednisolone in Adult Male Patients With Metastatic Castrate-Resistant Prostate Cancertreatment3completed
NCT00494338
Phase II Trial of Docetaxel and Celecoxib in Patients With Androgen Independent Prostate Cancertreatment2terminated
NCT01062503
Duration of Suppression of Bone Turnover Following Treatment With Zoledronic Acid in Men With Metastatic CRPCNot AvailableNot Availablecompleted
NCT06112990
Creatine Supplementation and Resistance Training to Preserve Muscle Mass and Attenuate Cancer ProgressionNo drug interventionstreatment3recruiting
NCT02049190
Phase 1-2 Study of Onapristone in Patients With Advanced Castration-resistant Prostate Cancertreatment1 / 2unknown_status
NCT04179864
A Study of Tazemetostat With Enzalutamide or Abiraterone/Prednisone in Participants With Advanced Prostate Cancertreatment1 / 2active_not_recruiting
NCT03934164
Molecular Stratification Profiling Protocol in Metastatic Castration Resistant Prostate Cancer (mCRPC) - MAESTRONo drug interventionsNot AvailableNot Availablerecruiting
NCT06359821
Evaluate Safety, Whole-Body Distribution and Radiation Dosimetry in Metastatic Castration Resistant Prostate CancerNo drug interventionsother0enrolling_by_invitation
NCT02962284
One-year, Open Extension to Evaluate the Treatment of Patients With Castration-Resistant Prostate Cancer With YONSA™treatment2completed
NCT00452387
Mitoxantrone, Prednisone Plus Sorafenib in Taxane-Refractory Metastatic Hormone Refractory Prostate Cancer (HRPC)treatment2terminated
NCT02744287
Safety and Activity Study of PSCA-Targeted CAR-T Cells (BPX-601) in Subjects With Selected Advanced Solid Tumorstreatment1 / 2suspended
NCT06479187
PSMAtrack-tracking Changes in PSMA-PET During Initial Therapy for Metastatic Hormone-sensitive Prostate Cancerdiagnostic4not_yet_recruiting
NCT05415787
Evaluation of the Technical Feasibility of Testing ct DNA for Homologous Recombination Gene Variants in Metastatic Prostate Cancer.No drug interventionsNot AvailableNot Availablecompleted
NCT04726033
64Cu-TLX592 Phase I Safety, PK, Biodistribution and Dosimetry Study (CUPID Study)No drug interventionstreatment0completed
NCT00003533
Antineoplaston Therapy in Treating Patients With Metastatic Prostate Cancertreatment2terminated
NCT04876651
The Present Study Aims to Compare Patients Who Receive the Investigational Product (177Lu-DOTA-rosopatamab) Plus Standard of Care, in Comparison to Standard of Care OnlyNo drug interventionstreatment3recruiting
NCT03763253
Additional Treatments to the Local Tumour for Metastatic Prostate Cancer: Assessment of Novel Treatment AlgorithmsNo drug interventionstreatment2recruiting
NCT03497377
Evaluation of 18F-DCFPyL PSMA- Versus 18F-NaF-PET Imaging for Detection of Metastatic Prostate Cancer.diagnostic1completed
NCT04786847
177Lu-DOTA-TLX591 Safety, Biodistribution and Dosimetry Studytreatment1completed
NCT06062745
Pilot Study for Detection of PSMA-Low CRPC-NE Tumors With Fluciclovine PET/CTdiagnostic1recruiting
NCT03493945
Phase I/II Study of Immunotherapy Combination BN-Brachyury Vaccine, M7824, N-803 and Epacadostat (QuEST1)treatment1 / 2active_not_recruiting
NCT01677897
Impact of the Addition of Metformin to Abiraterone in Metastatic Prostate Cancer Patientstreatment2completed
NCT04545697
mHealth ElectroNic COnsultation REcording (mENCORE) in Advanced Prostate CancerNo drug interventionshealth_services_researchNot Availablecompleted
NCT05983783
Comparing the Efficacy and Safety of Rezvilutamide+ADT+Docetaxel Versus Rezvilutamide +ADT in the mHSPCtreatment3recruiting
NCT05011383
High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancerstreatment2recruiting
NCT02066961
A Study to Describe Patterns of Care and Outcomes of Men Who Are at High Risk After Experiencing Biochemical Failure Following Definitive Prostate Cancer Therapy, Men With Castration-resistant Prostate Cancer and Men With Metastatic Prostate CancerNo drug interventionsNot AvailableNot Availablecompleted
NCT06582628
Talazoparib Plus Enzalutamide After Progression to Abiraterone in Metastatic Prostate Cancer: (TEAM PC)treatment2recruiting
NCT05590793
Effects of Triptorelin Pamoate 6-month When Given to Adult Chinese Participants With Advanced Cancer in the Prostatetreatment3completed
NCT00441571
Safety Study of a Radiolabeled Antibody (7E11) in Patients With Progressive Hormone Refractory Prostate Cancertreatment1unknown_status
NCT04031378
Single Dose Radiotherapy (SDRT) With or Without Adjuvant Systemic Therapy for Oligometastatic Prostate CancerNo drug interventionstreatment2unknown_status
NCT00942578
A Phase 2 Trial of Bevacizumab, Lenalidomide, Docetaxel, and Prednisone (ART-P) for Treatment of Metastatic Castrate-Resistant Prostate Cancertreatment2completed
NCT04070209
Management of Oligoprogressive Castration Resistant Prostate Cancer (PCS X)treatment2recruiting
NCT05617885
Neo-DAB: Darolutamide and Abemaciclib in Prostate Cancertreatment1 / 2active_not_recruiting
NCT03248570
Pembrolizumab in Metastatic Castration Resistant Prostate Cancer (mCRPC) With or Without DNA Damage Repair Defectstreatment2completed
NCT04528199
[18F]FLOR (FC303) PET/CT Imaging in Patients With Prostate CancerNo drug interventionsdiagnostic1terminated
NCT04887506
TAVT-45 (Abiraterone Acetate) Granules in Patients With Prostate Cancertreatment3completed
NCT06429813
Remotely Monitored Exercise Interventions in Patients With mCSPC Undergoing ADT (Prostate 006)No drug interventionssupportive_careNot Availablerecruiting
NCT01153113
Human Telomerase Reverse Transcriptase Messenger RNA (hTERT mRNA) Transfected Dendritic Cell VaccinesNo drug interventionstreatment1 / 2withdrawn
NCT04067713
Plasma Analysis for Response Assessment and to DIrect the manaGement of Metastatic Prostate CancerNo drug interventionsNot AvailableNot Availablerecruiting
NCT00599313
Phase II Sunitinib Prog Met AIPCtreatment2completed
NCT02051218
Prevention of Symptomatic Skeletal Events With Denosumab Administered Every 4 Weeks Versus Every 12 Weekssupportive_care3active_not_recruiting
NCT01558219
Second-line Chemotherapy in Castration Resistant Prostate CancerNo drug interventionstreatment2completed
NCT04951817
68Ga-PSMA PET/CT for Ra223 AssessmentNo drug interventionsdiagnosticNot Availablerecruiting
NCT02260817
Expanded Access to Diagnostic Imaging for Staging of Recurrent Prostate Cancerdiagnostic3completed
NCT04446117
Study of Cabozantinib in Combination With Atezolizumab Versus Second NHT in Subjects With mCRPCtreatment3active_not_recruiting
NCT03173924
18F-DCFPyL PSMA- Versus 18F-NaF-PET Imaging for Detection of Metastatic Prostate Cancerdiagnostic2active_not_recruiting
NCT03871816
A Study to Determine Frequency of DNA-repair Defects in Men With Metastatic Prostate CancerNo drug interventionsNot AvailableNot Availablecompleted
NCT05771896
Darolutamide With Radium-223 or Placebo and the Effect on Radiological Progression-Free Survival for Patients With mCSPCtreatment3withdrawn
NCT04533958
Evaluation of Hypnosis in Virtual Reality on the Anxiety of Patients With Metastatic Prostate Cancer Over ChemotherapyNo drug interventionssupportive_careNot Availableunknown_status
NCT04925063
The Effect of Metformin in Patients With Newly Diagnosed mHSPCtreatment2not_yet_recruiting
NCT01933022
A Study in Patients With Metastatic Prostate Cancer to Assess How the Drug Eligard®, Affects Certain Markers in Blood and Urine, Which Are Indicators for the Diseaseother4terminated
NCT03143322
Standard Treatment +/- SBRT in Solid Tumors Patients With Between 1 and 5 Bone-only MetastasesNo drug interventionstreatmentNot Availablerecruiting
NCT06439225
Platinum and Taxane Chemo in Met Castration Resistant Prostate Cancer Patients With Alterations in DNA Damage Response Genestreatment3not_yet_recruiting
NCT06329830
177Lu-PSMA, Niraparib/AA Plus Prednisone for Prostate Cancertreatment1 / 2not_yet_recruiting
NCT04193657
Toward a Comprehensive Supportive Care Intervention for Older or Frail Men With mCRPCNo drug interventionsNot AvailableNot Availablecompleted
NCT01233557
Biomarkers of Bone Resorption in Metastatic Prostate CancerNo drug interventionsNot AvailableNot Availablecompleted
NCT03867357
Intramuscular Mechanisms of Androgen Deprivation-related SarcopeniaNot AvailableNot Availablecompleted
NCT02380274
Observational Cohort Study of Patients With Castration-Resistant Prostate Cancer (CRPC)No drug interventionsNot AvailableNot Availablecompleted
NCT04335682
Androgen Receptor Directed Therapy on Cognitive Function in Patients Treated With Darolutamide or Enzalutamideother2recruiting
NCT05796973
Measuring Oncological Value of Exercise and Statintreatment3recruiting
NCT01923727
Phase I/IIA Study of PET Imaging With 89Zr-Df-IAB2M in Metastatic Prostate CancerNo drug interventionsdiagnostic1 / 2completed
NCT05933876
The Impact of Radiotherapy on Oligometastatic CancerNo drug interventionsNot AvailableNot Availablerecruiting
NCT04709276
A Study of Chemoimmunotherapy for the Treatment of Men With Neuroendocrine or Aggressive Variant Metastatic Prostate Cancertreatment2recruiting
NCT00216060
Risedronate to Prevent Skeletal Related Events in Patients With Metastatic Prostate Cancer Commencing Hormonal Therapyprevention3terminated
NCT00213694
PROSTACOX : Metastatic Prostate ChemotherapyNot AvailableNot Availablecompleted
NCT03939689
Study of I-131-1095 Radiotherapy in Combination With Enzalutamide in Patients With Metastatic Castration-resistant Prostate Cancer Who Are Chemotherapy Naive and Have Progressed on Abirateronetreatment2active_not_recruiting
NCT04787744
Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancertreatment2 / 3recruiting
NCT04332744
Enzalutamide Plus Talazoparib for the Treatment of Hormone Sensitive Prostate Cancer (ZZ-First)treatment2active_not_recruiting
NCT02500901
Enzalutamide and Niraparib in the Treatment of Metastatic Castrate-Resistant Prostate Cancer (CRPC)treatment1terminated
NCT05582772
TOward a comPrehensive Supportive Care Intervention for Older Men With Metastatic Prostate CancerNo drug interventionssupportive_careNot Availablerecruiting
NCT00255268
CMAB vs IMAB in Metastatic Prostate Cancertreatment4withdrawn
NCT03977610
The Role of Ga68-PSMA-11 PET Imaging in Prostate Cancer Patients Undergoing Androgen Deprivation TherapyNo drug interventionsdiagnosticNot Availablecompleted
NCT00541281
Safety and Efficacy Study of of Docetaxel vs Docetaxel Estramustine in Hormone Refractory Prostatic Cancertreatment2completed
NCT03585114
Prostate Cancer Monitoring Using [18F]DCFPyL and Blood Based Biomarkerstreatment2active_not_recruiting
NCT02278055
Non-Randomized Trial Assessing Pain Efficacy With Radium-223 in Symptomatic Metastatic Castration-Resistant Prostate Cancersupportive_care2completed
NCT01814150
The Association Between Alpha 1 Acid Glycoprotein Level and Outcome Metastatic Cancer Treated With DocetaxelNo drug interventionsNot AvailableNot Availableunknown_status
NCT05127850
MENCORE-2: Audio Recordings to Improve Decision-making in Advanced Prostate CancerNo drug interventionshealth_services_researchNot Availablecompleted
NCT04030338
Prostate-Specific Membrane Antigen (PSMA) PET Scans in People Prostate CancerNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT05413421
Study of ORIC-944 in Patients With Metastatic Prostate CancerNo drug interventionstreatment1recruiting
NCT00923221
Collection of Blood From Patients With Prostate CancerNo drug interventionsNot AvailableNot Availablerecruiting
NCT04478279
A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumorstreatment1 / 2active_not_recruiting
NCT00415779
ZANTE: Zometa and Taxotere in Hormone Refractory Prostate Cancertreatment1completed
NCT03673787
A Trial of Ipatasertib in Combination With Atezolizumabhealth_services_research1 / 2unknown_status
NCT04603833
A Study of SHR3680 in Combination With Docetaxel in the Treatment of mCRPCtreatment2unknown_status
NCT02407054
A Study of Enzalutamide and LY3023414 in Men With Prostate Cancertreatment2completed
NCT05078151
Whole-Body Diffusion-Weighted Magnetic Resonance Imaging (MRI) as a Response Biomarker for Metastatic Prostate CancerNo drug interventionsdiagnosticNot Availableunknown_status
NCT01718353
Early Switch From First-Line Docetaxel/Prednisone to Cabazitaxel/Prednisone and the Opposite Sequence, Exploring Molecular Markers in Men With Metastatic Castration-Resistant Prostate Cancer (mCRPC)treatment2completed
NCT03223597
Registry of Treatment Outcomes of Symptomatic Metastasized Castration Resistant Prostate Cancer Treated With Radium-223Not AvailableNot Availablecompleted
NCT04983628
Molecular Profiling in Prostate CancerNo drug interventionsNot AvailableNot Availableunknown_status
NCT02825628
Study of ODX (Osteodex) in Metastatic Castration Resistant Prostate Cancer (CRPC)No drug interventionstreatment2completed
NCT06141993
ARCTIC: Liquid Biomarkers in the Prospective Androgen Receptor Signaling Inhibitors (ARSI) Resistance Clinical TrialsNo drug interventionsNot AvailableNot Availablerecruiting
NCT05627778
68Ga-P15-041 and 68Ga-PSMA-11 PET/CT Imaging in the Same Group of Prostate Bone Metastasisdiagnostic1 / 2unknown_status
NCT05679388
A Study of Extending Relugolix Dosing Intervals Through Addition of Itraconazole or Ritonavir in Prostate Cancer Patientstreatment1recruiting
NCT04028388
ModraDoc006/r vs Docetaxel IV in Metastatic Prostate Cancertreatment2completed
NCT05361915
Study to Assess Abivertinib in Combination With Abiraterone in Metastatic Castration Resistant Prostate Cancertreatment2suspended
NCT03414437
Post-eRADicAte - A Long Term Follow up of Subjects That Completed the eRADicAte Study (NCT 02097303)No drug interventionsNot AvailableNot Availableunknown_status
NCT02074137
Evaluation of Safety of Cabazitaxel (Jevtana) in Patients With Metastatic Hormone Refractory Prostate Cancertreatment4completed
NCT04824937
Telaglenastat + Talazoparib In Prostate Cancertreatment2unknown_status
NCT04116775
Fecal Microbiota Transplant and Pembrolizumab for Men With Metastatic Castration Resistant Prostate Cancer.treatment2unknown_status
NCT02105675
Phase II Study of DCVAC/PCa Added to Standard Chemotherapy for Men With Metastatic Castration Resistant Prostate Cancertreatment2completed
NCT02378870
A Phase IIb Study to Evaluate Efficacy and Tolerability of ODX (Osteodex) in Metastatic CRPCNo drug interventionstreatment2terminated
NCT03089099
Expression of Molecular Markers in Circulating Tumor Cells of Metastatic Castration-Resistant Prostate CancerNo drug interventionsNot AvailableNot Availableunknown_status
NCT05457699
Ablative Radiotherapy to Consolidate Maximal Systemic Response in Metastatic Prostate Cancer (ANCHOR-Prostate)No drug interventionstreatment2recruiting
NCT04452136
Expanded Access Protocol of 68Ga PSMA 11 PET Imaging of Prostate CancerNot AvailableNot Availableapproved_for_marketing
NCT03843918
A Study on the Safety and Efficacy of LAE001 in the Treatment of Metastatic Prostate Cancertreatment1 / 2suspended
NCT01428219
Trial of Cabozantinib (XL184) in Castrate-Resistant Prostate Cancer Metastatic to Bonetreatment2terminated
NCT03569241
PEACE V: Salvage Treatment of OligoRecurrent Nodal Prostate Cancer MetastasesNo drug interventionstreatment2active_not_recruiting
NCT04833517
Prospective REgistry of Targeted RadionucLide TherapY in Patients With mCRPC (REALITY Study)No drug interventionsNot AvailableNot Availablerecruiting
NCT03761017
MGD019 DART® Protein in Unresectable/Metastatic Cancertreatment1active_not_recruiting
NCT04660617
A Multi-omics Study of Metastatic Prostate Cancer (MOSMPCA)No drug interventionsNot AvailableNot Availableunknown_status
NCT06136624
Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)treatment3recruiting
NCT03024216
Clinical Study of Atezolizumab (Anti-PD-L1) and Sipuleucel-T in Patients With Asymptomatic or Minimally Symptomatic Metastatic Castrate Resistant Prostate Cancertreatment1completed
NCT05563558
Pembrolizumab, Carboplatin and Cabazitaxel in Aggressive Metastatic Castration Resistant Prostate Cancer (PEAPOD_FOS)treatment2recruiting
NCT03434158
Olaparib Maintenance in Patients With MCRPC After Docetaxel Treatment Reaching Partial or Stable Response (IMANOL)treatment2completed
NCT01487863
Concurrent vs. Sequential Sipuleucel-T & Abiraterone Treatment in Men With Metastatic Castrate Resistant Prostate Cancerbasic_science2completed
NCT03655886
Cytoreductive Prostatectomy Versus Cytoreductive Prostate Irradiation as a Local Treatment Option for Metastatic Prostate Cancer: a Multicentric Feasibility TrialNo drug interventionstreatment2recruiting
NCT03696186
Selective Treatment According to Molecular Subtype of Prostate Cancertreatment2unknown_status
NCT03129139
A Phase 1, Multi-Center, Open-Label, Dose-Escalation, Safety, Pharmacokinetic, and Pharmacodynamic Study of Minnelide™ Capsules Given Alone or in Combination With Protein-Bound Paclitaxel in Patients With Advanced Solid Tumorstreatment1recruiting
NCT03775525
Study Evaluating GZ17-6.02 in Patients With Advanced Solid Tumors or in Combination With Capecitabine in Metastatic Hormone Receptor Positive Breast Cancertreatment1active_not_recruiting
NCT05283330
Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing TumorsNo drug interventionstreatment1recruiting
NCT06450548
Dynamic 68Ga-PSMA and 18F-FDG PET/CT Analysis Prior to 177Lu-PSMANo drug interventionsotherNot Availablenot_yet_recruiting
NCT02961257
Trial Evaluating the Safety of 2 Schedules of Cabazitaxel in Elderly Men With mCRPC Previously Treated With a Docetaxeltreatment3completed
NCT05002465
Clinical Use of 68Ga PSMA-11 PET/CT in Diagnosing, Staging and Restaging Prostate CancerNot AvailableNot Availableno_longer_available
NCT03295565
Optimal Sequencing of Treatment Options for Poor Risk mCRPC Previously Treated With Docetaxeltreatment2 / 3completed
NCT04781374
Neratinib in Patients With Metastatic Castration-Resistant Prostate Cancertreatment2withdrawn
NCT03951831
REGN2810 Followed by Chemoimmunotherapy for Newly Metastatic Hormone-sensitive Prostate Cancertreatment2active_not_recruiting
NCT03223727
Treatment Outcomes in a Non-study Population of Symptomatic mCRPC Patients Treated With Radium-223No drug interventionsNot AvailableNot Availablecompleted
NCT05000827
Dutch National Randomized Study: PSMA-PET/CT as a Triage Tool for Pelvic Lymph Node Dissection in Prostatectomy PatientsNo drug interventionsdiagnosticNot Availablerecruiting
NCT04590976
Metastatic Prostate Cancer Men's Attitudes Towards Treatment of the Local Tumour and Metastasis Evaluative ResearchNo drug interventionsNot AvailableNot Availablecompleted
NCT05570994
177Lu-HTK03170 in mCRPC With PSMA Positive Diseasetreatment1 / 2recruiting
NCT02485691
Cabazitaxel Versus the Switch to Alternative AR-targeted Agent (Enzalutamide or Abiraterone) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Patients Previously Treated With Docetaxel and Who Rapidly Failed a Prior AR-targeted Agenttreatment4completed
NCT03646162
Study of VERU-944 to Ameliorate Hot Flashes in Men With Advanced Prostate CancerNo drug interventionstreatment2completed
NCT05242744
FTT PET/CT in Metastatic Prostate CancerNo drug interventionsNot AvailableNot Availablerecruiting
NCT05067140
A Study of ARV-766 Given by Mouth in Men With Metastatic Prostate Cancertreatment1 / 2recruiting
NCT06320067
A Randomised Controlled Platform Trial Testing Treatments in Metastatic Hormone Sensitive Prostate Cancertreatment3recruiting
NCT02933801
ODM-201 Maintenance Therapy in Patients With mCRPC Previously Treated With Novel Hormonal Agents.treatment2terminated
NCT04483414
68Ga PSMA-11 PET/CT in Recurrent Prostate CancerNo drug interventionsdiagnostic2withdrawn
NCT03878823
Safety and Pharmacokinetics of ODM-209No drug interventionstreatment1 / 2completed
NCT03494803
Detection of Prostate Cancer With Non-invasive Method Based on DNA Methylation of Circulated Tumor DNA, PBMCNo drug interventionsNot AvailableNot Availablewithdrawn
NCT01322490
A Randomized, Double-blind, Phase 3 Efficacy Trial of PROSTVAC-V/F +/- GM-CSF in Men With Asymptomatic or Minimally Symptomatic Metastatic Castrate-Resistant Prostate CancerNo drug interventionstreatment3completed
NCT03833921
Evaluation of Response to Abiraterone/Prednisone by Race/Ethnicity and Other Factors in Metastatic Hormone Naive Prostate Cancertreatment2recruiting
NCT05384002
An AI Platform Integrating Imaging Data and Models, Supporting Precision Care Through Prostate Cancer's ContinuumNo drug interventionsNot AvailableNot Availablerecruiting
NCT01595087
A Phase I/II Study of ODX (Osteodex) in Metastatic Castration Resistant Prostate Cancer (CRPC)No drug interventionstreatment1 / 2completed
NCT02815033
Imaging Staging and Response Prediction in Metastatic Hormono-Sensitive Prostate Cancer Patients Receiving Enzalutamidetreatment2completed
NCT03129854
Androgen Deprivation Therapy (ADT) Versus ADT Plus Prostate Cryotherapy for Metastatic Prostate Cancer (mPCa)No drug interventionstreatmentNot Availablerecruiting
NCT06430411
Outcomes of Local Treatment for Oligometastatic Prostate Cancer Diagnosed Using PSMA PET Imaging: OLIGOMET StudyNot AvailableNot Availablenot_yet_recruiting
NCT05352178
Metastasis-directed Therapy for Oligorecurrent Prostate CancerNo drug interventionstreatment3recruiting
NCT04641078
Stereotactic Body Radiotherapy With or Without Darolutamide for OligoRecurrent Prostate Cancertreatment2recruiting
NCT02964988
uPAR PET/CT in Radium-223-dichloride Treatment of Patients With Metastatic Castration-resistant Prostate CancerNo drug interventionsdiagnostic2terminated
NCT03436485
Safety and Pharmacokinetics of ODM-208 in Patients With Metastatic Castration-resistant Prostate Cancertreatment1 / 2active_not_recruiting
NCT05655715
Checkpoint Inhibitors and SBRT for mCRPCtreatment2recruiting
NCT04848337
Pembrolizumab and Lenvatinib in Advanced/Metastatic Neuroendocrine Prostate Cancertreatment2recruiting
NCT03490032
68Ga-PSMA-R2 in Patients With Biochemical Relapse (BR) and Metastatic Prostate Cancer (mPCa)No drug interventionsdiagnostic1 / 2completed
NCT03362359
Ga-68-PSMA-11 in High-risk Prostate CancerNo drug interventionsdiagnostic1 / 2completed
NCT05567770
ACTInium-J591 Radionuclide Therapy in PSMA-Detected Metastatic HOrmone-Sensitive Recurrent Prostate CaNcertreatment1withdrawn
NCT05177042
Trial of ARV-110 and Abiraterone in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)treatment1active_not_recruiting
NCT03693742
MSG Use With 18F-DCFPyL PET/CT ImagingNo drug interventionsdiagnosticNot Availablecompleted
NCT04916613
ADT +/- Darolutamide in de Novo Metastatic Prostate Cancer Patients With Vulnerable Functional Ability (PEACE6-Vulnerable)treatment3recruiting
NCT03575819
A Phase 1 Study of FOR46 in Patients With Metastatic Castration-Resistant Prostate Cancer (mCRPC)No drug interventionstreatment1completed
NCT06242119
Clinical Application of the J-PET Scanner PrototypeNo drug interventionsNot AvailableNot Availablerecruiting
NCT02913196
Phase I Trial of Apalutamide Plus Abiraterone Acetate, Docetaxel, and Prednisone in Patients With mCRPCtreatment1active_not_recruiting
NCT03658486
Exercise for Advanced Prostate Cancer: a Multicomponent Feasibility TrialNo drug interventionsotherNot Availablecompleted
NCT03988686
Testing Radical Prostatectomy in Chinese Men With Prostate Cancer and oligoMetastases to the BoneNo drug interventionstreatmentNot Availableunknown_status
NCT06171139
Tumor Genomic Pre-test Counseling Tool for Black or African-American Men With Prostate CancerNo drug interventionshealth_services_researchNot Availablerecruiting
NCT05553639
HB-302/HB-301 Therapy in Participants With Metastatic Castration-Resistant Prostate CancerNo drug interventionstreatment1 / 2terminated
NCT05327465
Exercise to Enhance Cardiovascular Health Among Black Prostate Cancer Patients With Androgen Deprivation TherapyNo drug interventionssupportive_careNot Availablerecruiting
NCT03396874
Gallium-68 PSMA-11 PET in Patients With Biochemical Recurrencediagnostic2completed
NCT04019327
A Study of the Drugs Talazoparib and Temozolomide in Prostate Cancertreatment1 / 2active_not_recruiting
NCT04776889
The Prognosis of Lipid Reprogramming With Rosuvastatin, in Castrated Egyptian Prostate Cancer Patientstreatment4completed
NCT06461689
Comparison of Changes in Tumor Burden in 68Ga-PSMA-11 PET/CT and 177Lu-PSMA SPECT/CT in Metastatic Castration-resistant Prostate CancerNot AvailableNot Availablenot_yet_recruiting
NCT05276492
Decreasing Dosing Regimens of Abiraterone 500 mg in Men With Prostate Cancer to Find Lowest Recommended Dose.treatment1active_not_recruiting
NCT06251492
Radiation and Adebrelimab in Prostate Cancer With Imaging-measurable Disease (RAPID)treatment2recruiting
NCT01360840
EMD 525797 in Subjects With Asymptomatic or Mildly Symptomatic Metastatic Castrate-resistant Prostate Cancertreatment2completed
NCT02814968
PET/CT and WB MRI for Staging and Response in CRPC Patients Receiving Enzalutamidetreatment2completed
NCT04179968
The Role of 68Gallium PSMA-11 in Enhancing Diagnosis of Primary and Metastatic Prostate CancerNo drug interventionsdiagnostic2completed
NCT03888612
Trial of ARV-110 in Patients With Metastatic Castration Resistant Prostate Cancertreatment1 / 2active_not_recruiting
NCT06260410
Data Collection in Lutetium Treated Prostate Cancer: Recording of Progression and Tumor CharacteristicsNo drug interventionsNot AvailableNot Availablerecruiting
NCT06496581
Standard of Care +/- 177Lu-PSMA-617 In de Novo mHSPC Patients With Poor PSA Response (PEACE6-Poor Responders)treatment3not_yet_recruiting
NCT03507595
Evaluation of the Metastasis and Recurrence of Prostate CancerNo drug interventionsNot AvailableNot Availableunknown_status
NCT03413995
Trial of Rucaparib in Patients With Metastatic Hormone-Sensitive Prostate Cancer Harboring Germline DNA Repair Gene Mutationstreatment2active_not_recruiting
NCT04983095
Metastasis Directed Stereotactic Body Radiotherapy for Oligo Metastatic Hormone Sensitive Prostate CancerNo drug interventionstreatment3recruiting
NCT05530395
BAseLine TEstosterone as a Prognostic and/or Predictive bioMARKer in mHSPCNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT03850795
HC-1119 Versus Enzalutamide in Metastatic Castration-Resistant Prostate Cancer (mCRPC)treatment3terminated
NCT03784755
Local Ablative Therapy For Hormone Sensitive Oligometastatic Prostate CancerNo drug interventionstreatmentNot Availablerecruiting
NCT06215508
Geriatric Assessment and Technology Evaluation in Prostate CancerNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT04086290
National Danish Protocol. Surgery+ SBRT for M1 Prostate Cancer PatientsNo drug interventionstreatment1 / 2recruiting
NCT02379390
Cabazitaxel Versus the Switch to Alternative AR Targeted Therapy Enzalutamide or Abiraterone in Metastatic Castration-Resistant Prostate Cancer (mCRPC) Primary Resistant Patients to Abiraterone or Enzalutamidetreatment2terminated
NCT06165302
Exercise in Prostate CancerNo drug interventionsotherNot Availablenot_yet_recruiting
NCT03739684
Study of 18F-DCFPyL PET/CT Imaging in Patients With Suspected Recurrence of Prostate Cancerdiagnostic3completed
NCT01254279
Early Access to Cabazitaxel in Patients With Metastatic Hormone Refractory Prostate Cancer Previously Treated With a Docetaxel-containing Regimentreatment3completed