This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Fluorocholine F-18 is a radiopharmaceutical indicated in PET scans of the prostate.

Generic Name
Fluorocholine F-18
DrugBank Accession Number
DB15887
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
Thumb
Weight
Average: 105.166
Monoisotopic: 105.10518851
Chemical Formula
C5H13FN
Synonyms
  • (18F)Fluorocholine
  • 18F-FCH
  • Fluorocholine(18F)
  • Fluourine-18 Fluoromethylcholine

Pharmacology

Indication

Not Available

Pharmacology
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Associated Conditions
Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Adverseeffects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

Products2
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Product Ingredients
IngredientUNIICASInChI Key
Fluorocholine chloride F-187DKH3NEJ7F371173-14-7QJEHIIJVWXGJAB-ZZCPHWBCSA-M

Categories

ATC Codes
V09IX07 — Fluorocholine(18f)
Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
700YTQ6F2B
CAS number
407582-13-2
InChI Key
WOAGQHQTBSCFJV-KWCOIAHCSA-N
InChI
InChI=1S/C5H13FN/c1-7(2,3)5-4-6/h4-5H2,1-3H3/q+1/i6-1
IUPAC Name
[2-(¹⁸F)fluoroethyl]trimethylazanium
SMILES
C[N+](C)(C)CC[18F]

References

General References
  1. BASG Product Information: Fluorochol ((18F)Fluorocholine) injection [Link]
ChemSpider
8187432

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4Unknown StatusDiagnosticBreast Cancer Diagnosis / Magnetic Resonance Imaging (MRI) / Positron Emission Tomography1
3CompletedDiagnosticProstate Cancer1
3RecruitingDiagnosticMultiple Myeloma (MM)1
3Unknown StatusDiagnosticProstate Cancer1
2Not Yet RecruitingOtherNon-Resectable Hepatocellular Carcinoma1
Not AvailableCompletedDiagnosticProstate Cancer1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Injection, solutionParenteral222 MBq/ml
Injection, solutionParenteral1 GBq/ml
Injection, solutionIntravenous
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.284 mg/mLALOGPS
logP-2.8ALOGPS
logP-3.8ChemAxon
logS-2.7ALOGPS
Physiological Charge1ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count2ChemAxon
Refractivity40.5 m3·mol-1ChemAxon
Polarizability11.71 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created at September 25, 2020 21:47 / Updated at May 07, 2021 21:08