This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Summary
Fluorocholine F-18 is a radiopharmaceutical indicated in PET scans of the prostate.
- Generic Name
- Fluorocholine F-18
- DrugBank Accession Number
- DB15887
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
Structure for Fluorocholine F-18 (DB15887)
- Weight
- Average: 105.166
Monoisotopic: 105.10518851 - Chemical Formula
- C5H13FN
- Synonyms
- (18F)Fluorocholine
- 18F-FCH
- Fluorocholine(18F)
- Fluourine-18 Fluoromethylcholine
Pharmacology
- Indication
Not Available
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Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Diagnostic agent Prostate cancer metastatic disease •••••••••••• ••••• •••••••••• •••••••• Diagnostic agent Recurrent prostate cancer •••••••••••• ••••• •••••••••• •••••••• - Contraindications & Blackbox Warnings
Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
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Ingredient UNII CAS InChI Key Fluorocholine chloride F-18 7DKH3NEJ7F 371173-14-7 QJEHIIJVWXGJAB-ZZCPHWBCSA-M
Categories
- ATC Codes
- V09IX07 — Fluorocholine(18f)
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 700YTQ6F2B
- CAS number
- 407582-13-2
- InChI Key
- WOAGQHQTBSCFJV-KWCOIAHCSA-N
- InChI
- InChI=1S/C5H13FN/c1-7(2,3)5-4-6/h4-5H2,1-3H3/q+1/i6-1
- IUPAC Name
- [2-(¹⁸F)fluoroethyl]trimethylazanium
- SMILES
- C[N+](C)(C)CC[18F]
References
- General References
- BASG Product Information: Fluorochol ((18F)Fluorocholine) injection [Link]
- External Links
- ChemSpider
- 8187432
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 4 Unknown Status Diagnostic Breast Cancer Diagnosis / Magnetic Resonance Imaging (MRI) / Positron Emission Tomography 1 3 Completed Diagnostic Prostate Cancer 1 3 Recruiting Diagnostic Multiple Myeloma (MM) 1 3 Unknown Status Diagnostic Prostate Cancer 1 2 Recruiting Other Non-Resectable Hepatocellular Carcinoma 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Injection, solution Intravenous 222 MBq/ml Injection, solution Parenteral 222 MBq/ml Injection, solution Intravenous Injection, solution Parenteral 1 GBq/ml Injection, solution Intravenous 1 GBq/ml - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.284 mg/mL ALOGPS logP -2.8 ALOGPS logP -3.8 Chemaxon logS -2.7 ALOGPS Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 0 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 0 Å2 Chemaxon Rotatable Bond Count 2 Chemaxon Refractivity 40.5 m3·mol-1 Chemaxon Polarizability 11.71 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted 1H NMR Spectrum 1D NMR Not Applicable Predicted 13C NMR Spectrum 1D NMR Not Applicable - Chromatographic Properties
Collision Cross Sections (CCS)
Not Available
Drug created at September 25, 2020 21:47 / Updated at May 07, 2021 21:08