Erythema Nodosum Leprosum (DBCOND0036567)
Identifiers
- Synonyms
- Erythema nodosum leprosum / Type 2 lepra reaction / Immune complex reaction co-occurrent and due to multibacillary leprosy (disorder)
Associated Data
- Indicated Drugs and Targets
Drug Description Targets Thalidomide A medication used to treat cancers, particularly newly diagnosed multiple myeloma, and erythema nodosum leprosum.- Cytochrome P450 2C19enzyme
- Cytochrome P450 2C9enzyme
- Prostaglandin G/H synthase 1enzyme
- Prostaglandin G/H synthase 2enzyme
- Cytochrome P450 3A5enzyme
- DNAtarget
- Protein cereblontarget
- alpha1-acid glycoproteintarget
- Cytochrome P450 3A4enzyme
- Cytochrome P450 1A1enzyme
- Cytochrome P450 2B6enzyme
- Tumor necrosis factortarget
- Clinical Trials
Identifier Title Drug(s) Purpose Phase Status NCT00406861 Montelukast in ENL Reaction treatment Not Available unknown_status NCT03775460 Methotrexate and Prednisolone Study in Erythema Nodosum Leprosum treatment Not Available recruiting NCT03807362 CC-11050 Trial in Nepalese Patients With Erythema Nodosum Leprosum treatment 2 recruiting NCT04822909 A Study to Evaluate the Efficacy and Safety of Apremilast in Patients of Chronic and Recurrent Erythema Nodosum Leprosum treatment 4 completed