Bacterial Infections (DBCOND0027917)

Identifiers

Synonyms
Bacterial Infection / Infections, Bacterial / Infection, Bacterial / Bacterial infections NEC / Infections - Bacterial / Bacterial infection, unspecified / Bacterial infectious disease (disorder) / Bacterial infection of unspecified site / Bacterial infectious disorders / Bacterial infection NOS / Infection bacterial

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Amoxicillin
A penicillin derivative used for the treatment of infections caused by gram-positive bacteria, in particular streptococcal bacteria causing upper respiratory tract infections.
Ampicillin
A penicillin derivative used for the treatment of a variety of infections caused by gram-positive and gram-negative bacteria as well as some anaerobes.
Avibactam
A non-β-lactam β-lactamase inhibitor used in combination with ceftazidime for the treatment of complicated intra-abdominal infections, complicated urinary tract infections, and hospital or ventilator-acquired pneumonia.
Bacitracin
A cyclic polypeptide antibiotic used to prevent wound infections, treat pneumonia and empyema in infants, and to treat skin and eye infections.
Benzoic acid
An antimicrobial food additive.
Betamethasone
A systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders.
Bronopol
An antimicrobial compound used as a biocide and preservative.
Cefaclor
A second generation cephalosporin used to treat a wide variety of infections in the body.
Cefadroxil
A cephalosporin antibiotic used in the treatment of various bacterial infections, such as urinary tract infections, skin and skin structure infections, and tonsillitis.
Cefditoren
A broad-spectrum third-generation cephalosporin antibiotic typically used to treat bacterial infections of the skin and respiratory tract.
Cefepime
A fourth-generation cephalosporin antibiotic used in the treatment of infections caused by susceptible bacteria, such as pneumonia, urinary tract infections, and skin infections.
Cefoperazone
A broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, including the respiratory tract, abdomen, skin, and female genital tracts.
Cefotetan
An antibiotic medication used for the prophylaxis and treatment of various bacterial infections, including urinary tract infections, bone and joint infection, and lower respiratory tract infections.
Cefoxitin
A semi-synthetic, broad-spectrum antibiotic for parenteral administration used for the treatment of serious bacterial infections, such as urinary tract infection, blood infection, bone and joint infection, and lower respiratory tract infection.
Cefpodoxime
A third-generation cephalosporin antibiotic used in the treatment of various bacterial infections, including gonorrhea, community acquired pneumonia, and sinusitis.
Cefprozil
A cephalosporin antibiotic used in the treatment of various bacterial infections, such as pharyngitis, tonsillitis, otitis media, and uncomplicated skin infections.
Ceftazidime
An injected broad-spectrum third-generation cephalosporin beta-lactam antibiotic used to treat or prevent a variety of bacterial infections, including pneumonia, gynecological infections, bone and joint infections, and septicemia, among others.
Ceftibuten
A third-generation cephalosporin antibiotic commonly used in the treatment of acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsillitis.
Ceftizoxime
A third-generation cephalosporin antibiotic used in the treatment of various bacterial infections, including lower respiratory tract infection, urinary tract infection, and gonorrhea.
Ceftriaxone
A broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, such as in the respiratory tract, skin, soft tissue, and urinary tract.
Cefuroxime
A cephalosporin indicated for the treatment of a variety of infections including acute bacterial otitis media, several upper respiratory tract infections, skin infections, urinary tract infections, gonorrhea, early Lyme disease, and impetigo.
Chloramphenicol
A broad spectrum antibiotic that is effective against a variety of susceptible and serious bacterial infections but is not frequently used because of its high risk of bone marrow toxicity.
Clarithromycin
A macrolide antibiotic used for the treatment of a wide variety of bacterial infections such as acute otitis, pharyngitis, tonsillitis, respiratory tract infections, uncomplicated skin infections, and helicobacter pylori infection.
Clavulanic acid
A beta lactamase inhibitor used to enhance the effectiveness of beta lactam antibiotics.
Colistimethate
An antibiotic indicated for treatment of infections caused by susceptible strains of certain gram-negative bacilli. It is particularly useful for targeting sensitive strains of Pseudomonas aeruginosa.
Dalfopristin
An antibiotic used with quinupristin to treat severe or life-threatening infections of vancomycin-resistant Enterococcus faecium (VREF), and skin infections caused by methicillin susceptible staphylococcus aureus or streptococcus pyogenes.
Dexamethasone
A glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
Diazolidinylurea
An ingredient used in hospitals for disinfection.
No drug targets
Doripenem
An antibiotic of the penem class used to treat complicated intra-abdominal and urinary tract infections.
Erythromycin
A macrolide antibiotic used to treat and prevent a variety of bacterial infections.
Ethanol
For therapeutic neurolysis of nerves or ganglia for the relief of intractable chronic pain in such conditions as inoperable cancer and trigeminal neuralgia (tic douloureux), in patients for whom neurosurgical...
Gemifloxacin
A quinolone antibacterial agent used for the treatment of acute bacterial exacerbation of chronic bronchitis and mild to moderate community-acquired pneumonia caused by susceptible bacteria.
Gentamicin
An aminoglycoside used to treat a wide variety of aerobic infections in the body.
Hexachlorophene
A chlorinated bisphenol antiseptic used as a surgical scrub and skin cleanser.
Human immunoglobulin G
A purified form of human immunoglobulin G and other proteins used to treat immunodeficiency and a wide variety of autoimmune disorders.
Josamycin
A macrolide antibiotic used for the treatment of various susceptible bacterial infections.
Meropenem
A carbapenem antibiotic used to treat a wide variety of infections in the body.
Nafcillin
A penicillin derivative antibiotic used to treat susceptible staphylococcal infections.
Netilmicin
An aminoglycoside used to treat a wide variety of infections in the body.
Nystatin
A polyene ionophore antifungal used to treat cutaneous, mucocutaneous, and gastrointestinal mycotic infections, particularly those caused by Candida species.
Ofloxacin
An antibacterial agent used for the treatment of bacterial infections in many parts of the body, including the respiratory tract, kidney, skin, soft tissue, and urinary tract.
Phenoxymethylpenicillin
A penicillin antibiotic used to prevent and treat mild to moderately severe infections in the respiratory tract, skin, and soft tissues.
Piperacillin
A penicillin antibiotic combined with tazobactam to treat piperacillin-resistant, piperacillin/tazobactam­ susceptible, β-lactamase generating strains of several bacteria.
Polymyxin B
A polymyxin antibiotic used to treat a wide variety of infections in the body.
Prednisolone phosphate
A corticosteroid used to treat inflammation, immune reactions, as well as endocrine or neoplastic conditions.
Probenecid
A medication used to treat gouty arthritis, tophaceous gout, and hyperuricemia.
Procaine benzylpenicillin
A local anesthetic and antibiotic combination for intramuscular injection to treat a variety of bacterial infections while reducing pain from a deep intramuscular injection.
No drug targets
Quinupristin
An antibiotic agent used in the treatment of serious vancomycin-resistant Enterococcus faecium bacteremia as well as complicated skin and skin structure infections.
Rifaximin
A rifamycin-based non-systemic antibiotic used for the treatment of gastrointestinal bacterial infections, such as traveler's diarrhea and irritable bowel syndrome, and reduction of overt hepatic encephalopathy recurrence in adults.
Spiramycin
A macrolide antimicrobial agent used in the treatment of various bacterial infections.
Sulbactam
An beta-lactamase inhibitor antibiotic combined with other antibiotics to treat a variety of susceptible bacterial infections.
Sulbactam pivoxil
A prodrug of a beta-lactamase inhibitor used to improve the efficacy of beta lactam antibiotics
No drug targets
Sulfaguanidine
Not Annotated
No drug targets
Sulfamerazine
An antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections.
Sulfathiazole
Sulfathiazole is effective against a wide range of gram positive and gram negative pathogenic microorganisms. Although no longer used in humans, it is used in cattle.
Telavancin
An antibacterial agent used in the treatment of complicated skin and skin structure infections and types of hospital-acquired bacterial pneumonia.
Tetracycline
An antibiotic used to treat a wide variety of susceptible infections.
Tigecycline
A glycylcycline antibiotic used to treat a number of susceptible bacterial infections.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT05106803
Antibiotic Profile of Pathogenic Bacteria Isolated in Public Hospitals in Northern JordanNot AvailableNot Availablecompleted
NCT04633603
LázBarát™ (FeverFriend™) Projekt: Attitude Toward Fever and Its Change in the Healthcare SystemNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT01949103
TD-1607 MAD Study in Healthy SubjectsNo drug interventionstreatment1completed
NCT01111864
Changes in Microbiota and Iron Status After Iron Fortification of Complementary FoodsNo drug interventionsbasic_scienceNot Availablecompleted
NCT03243864
Study of Ceftazidime-Avibactam Blood Concentrations in Intensive Care Unit Patients With Renal Failure Requiring Continuous DialysisNot AvailableNot Availableunknown_status
NCT03537664
Adjunctive Steps for Disinfection of Teeth With Primary Endodontic InfectionsNo drug interventionstreatmentNot Availablecompleted
NCT03846921
Alpha-defensin as a Diagnostic Means to Distinguish Between Acute Bacterial and Viral InfectionsNo drug interventionsNot AvailableNot Availableunknown_status
NCT00714402
Procalcitonin Level and Kinetics in Children With Bacterial InfectionsNo drug interventionsNot AvailableNot Availablecompleted
NCT05722184
Diagnostic Evaluation Study of the BactInsight Blood Culture System in West-AfricaNo drug interventionsNot AvailableNot Availablerecruiting
NCT01553279
Immunogenicity and Safety of V419 (PR51) in Combination With MCC in Infants and Toddlers (V419-011)prevention3completed
NCT01897779
Safety, Tolerability, Pharmacokinetics of Intravenous RPX2014 and RPX7009 in Healthy Adult Subjectstreatment1completed
NCT03450187
A Phase 1 TP-271 Oral PK Multiple Ascending Dose Studyother1completed
NCT00945087
Experimental Phage Therapy of Bacterial InfectionsNo drug interventionsNot AvailableNot Availableunknown_status
NCT03858387
PK/PD and Clinial Outcomes of Beta-lactams in ICU PatientsNot AvailableNot Availableunknown_status
NCT05100433
Effect of Passive Ultrasonic Irrigation on Bacteria That Persist After Root Canal PreparationNo drug interventionstreatmentNot Availablecompleted
NCT02214433
A Multiple Dose Study of Debio 1450 [Intravenous (IV) and Oral] in Healthy Volunteersbasic_science1completed
NCT00736554
What is the Prevalence of Methicillin-Resistant Staphylococcus Aureus in Skin and Soft Tissue Infections Presenting to the Emergency Departments of a Canadian Academic Health Care Center?No drug interventionsNot AvailableNot Availablecompleted
NCT06547554
A DDI Study to Investigate PK and Safety of Cefiderocol in Combination With Xeruborbactam in Healthy Adult Participantstreatment1not_yet_recruiting
NCT01746654
Safety & Efficacy of an Antibacterial Protein Molecule Applied Topically to the Nostrils of Volunteers and PatientsNo drug interventionsprevention1 / 2completed
NCT03941951
Study to Optimize the Use of New AntibioticsNo drug interventionstreatmentNot Availableunknown_status
NCT05336851
Emergency PWAS in Respiratory Infectious DiseaseNo drug interventionsNot AvailableNot Availablerecruiting
NCT02979951
Fosfomycin i.v. for Treatment of Severely Infected PatientsNo drug interventionsNot AvailableNot Availablerecruiting
NCT00515151
Prevention of Catheter-Associated Infection With the Skin Disinfectant Octenidine Dihydrochlorideprevention4completed
NCT00008853
Evaluation of Two Type III GBS Polysaccharide-Tetanus Toxoid Conjugate VaccinesNo drug interventionsprevention1completed
NCT06322277
Use of Low-cost Molecular Diagnostic Techniques as a New Surveillance Model for Diseases Preventable by Vaccinations.No drug interventionspreventionNot Availablerecruiting
NCT00564447
Study of AzaSite (Azithromycin) Versus Vigamox in the Conjunctiva of Healthy Volunteerssupportive_care4completed
NCT04777747
The Role of Lactate in Viral and Bacterial InfectionNo drug interventionsNot AvailableNot Availablecompleted
NCT00004747
Phase II Randomized, Double-Blind, Placebo-Controlled Study of Intravenous Mucoid Exopolysaccharide Pseudomonas Aeruginosa Immune Globulin for Cystic FibrosisNo drug interventionstreatment2completed
NCT03016845
Pharmacokinetics of Ciprofloxacin in Critically Ill PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT00488345
Study Evaluating the Pharmacokinetics (PK), Safety, and Tolerability of Tigecycline in Patients 8 to 11 Years of Agetreatment2completed
NCT05611905
Biodistribution and Pathophysiology Study of 11C-para-aminobenzoic AcidNot AvailableNot Availablerecruiting
NCT05960383
Molecular vs Conventional Microbiologic Diagnosis for Infections in Lung TransplantationNo drug interventionsNot AvailableNot Availablerecruiting
NCT00431483
Clinical and Economic Impact of Interventions by a Clinical Pharmacist on Antibiotic Use on Surgical WardsNo drug interventionshealth_services_researchNot Availablecompleted
NCT05587283
Safety, Tolerability, and Acceptability Study of Intravaginal Administration of LABTHERA-001 Capsules in Healthy Womenother1recruiting
NCT00044928
Study Evaluating Zosyn in Hospitalized Patients With Intra-abdominal Infectiontreatment4completed
NCT00000811
A Study to Compare Different Drugs Used to Prevent Serious Bacterial Infections in HIV-Positive Childrentreatment2completed
NCT02031588
Impact of Ceftriaxone and/or Fluoroquinolone (FQ) Treatment on the Gut Microbiota of Hospitalized Patients.No drug interventionsNot AvailableNot Availableterminated
NCT01839188
Spanish Mixed HEXA/PENTA/HEXA Schedule (V419-010)prevention3completed
NCT04380207
P1 Single and Multiple Ascending Dose (SAD/MAD) Study of IV QPX7728 Alone and Combined With QPX2014 in NHVNo drug interventionstreatment1completed
NCT03079609
The Search for Viral and Bacterial Etiology of VaricoceleNo drug interventionsbasic_scienceNot Availableunknown_status
NCT03667937
Effectiveness of a Hydrophobic Dressing for Microorganisms' Colonization and Infection Control of Vascular UlcersNo drug interventionstreatment4unknown_status
NCT05217537
Study to Evaluate the PK of IV and PO Omadacycline in Children and Adolescents With Suspected or Confirmed Bacterial Infectionsother1recruiting
NCT06519032
Development and Evaluation of Rapid Bacterial Species Identification for Acid-Fast Bacilli Smear Using Image Analysis AINo drug interventionsNot AvailableNot Availablerecruiting
NCT03332732
VNRX-5133 Drug-Drug Interaction in Healthy Adult Volunteersbasic_science1completed
NCT03627000
Microbiological Epidemiology in Patients Experiencing Microbiological or Clinical Failure Following Reimplantation After a 2-stage Exchange Strategy for Hip or Knee Prosthetic Joint InfectionNo drug interventionsNot AvailableNot Availablecompleted
NCT06103500
Integrated Clinical Decision Support for Empiric Antibiotic Selection in SepsisNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT03590600
A Single Ascending Dose Study of BTZ043treatment1completed
NCT02955459
VNRX-5133 SAD/MAD Safety and PK in Healthy Adult Volunteersbasic_science1completed
NCT01074775
Human Innate Immune Responses To Mycobacterial Aerodigestive Tract InfectionNo drug interventionsbasic_scienceNot Availablecompleted
NCT03915275
Clinical Impact of 16S rDNA PCRNo drug interventionsNot AvailableNot Availableunknown_status
NCT06079775
P1, DDI & MAD PK and Safety Study of Xeruborbactam Oral Prodrug in Combo With Ceftibuten in Healthy Participantstreatment1recruiting
NCT01839175
Concomitant Administration of a New Hexavalent Vaccine With a Meningococcal Serogroup C Conjugate Vaccine in Healthy Infants During Primary Series Immunisation Followed by Booster Vaccinationprevention3completed
NCT06157242
PK & Safety Study of Xeruborbactam Oral Prodrug Combined With Ceftibuten in Participants With Renal Impairmenttreatment1not_yet_recruiting
NCT02162199
A Single Dose Study of Debio 1450 in Healthy SubjectsNo drug interventionsbasic_science1completed
NCT00678106
Study Of Dalbavancin Drug Levels Achieved In Hospitalized Adolescents Who Are Receiving Antibiotic Therapy For Bacterial InfectionsNot Available1completed
NCT02687906
Dose-finding, Pharmacokinetics, and Safety of VABOMERE in Pediatric Subjects With Bacterial Infectionstreatment1recruiting
NCT01702649
Safety, Tolerability, Pharmacokinetics of Intravenous RPX2003 (Biapenem) in Healthy Adult Subjectstreatment1completed
NCT01788449
Study Evaluating the Association of Antibiotic Measures and Control of Bacterial ResistanceNo drug interventionsNot AvailableNot Availablecompleted
NCT01772836
Safety Study of Intravenous Biapenem (RPX2003) and RPX7009 Given Alone and in Combinationtreatment1completed
NCT05350813
Impact of Procalcitonin-guided Algorithm on Early Discontinuation of Antibiotic TherapyNo drug interventionspreventionNot Availablerecruiting
NCT01402713
To Evaluate the Effectiveness(Immunogenicity) and Safety of 'GC1107' Administered Intramuscularly in Healthy ChildrenNo drug interventionsprevention2 / 3completed
NCT05293418
Incidence of Colonization by Multidrug-resistant Organisms in Mechanically Ventilated Patients With Severe COVID-19No drug interventionsNot AvailableNot Availablecompleted
NCT06174519
Evaluation of the Artificial Intelligence-based Prescription Support Software iAST® for the Choice of Empirical and Semi-targeted Antibiotic TreatmentNo drug interventionsNot AvailableNot Availablecompleted
NCT01018641
An Evaluation Of Three Dose Levels Of 3-Antigen Staphylococcus Aureus Vaccine (SA3Ag) In Healthy AdultsNo drug interventionsprevention1completed
NCT03024034
A Phase 1 TP-271 Oral PK Single Ascending Dose Studyother1completed
NCT03726216
Xydalba Utilization Registry in FranceNot AvailableNot Availablecompleted
NCT02814916
Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections in Children, Known or Suspected to be Caused by Susceptible Gram-positive Organisms, Including MRSAtreatment3completed
NCT00205816
Study Evaluating Emergency-use Tigecycline in Subjects With Resistant Pathogens.treatment3completed
NCT03053258
Diagnostic Breath Analysis for Detection of Ventilator Acquired Pneumonia (VAP)No drug interventionsNot AvailableNot Availablecompleted
NCT04764058
Efficacy and Safety of Colistin Based Antibiotic Therapyother1 / 2unknown_status
NCT06319235
Clinical Trial to Demonstrate the Safety and Efficacy of DUOFAG®treatment1 / 2recruiting
NCT03361163
Controlled Human Infection for Vaccination Against Streptococcus PyogenesNo drug interventionsbasic_science1completed
NCT05498363
Bacteriophage Therapy of Difficult-to-treat InfectionsNo drug interventionsNot AvailableNot Availablecompleted
NCT00002139
Phase I Study of the Clinical Pharmacology of Azithromycin in Buffy Coat of HIV-Infected Subjects.treatment1completed
NCT03424525
11C-Trimethoprim PET/CT Imaging to Evaluate Biodistribution and Kinetics in Human Subjectsbasic_science1active_not_recruiting
NCT06100848
Hydrogen Peroxide Fumigation in Dental Office EnvironmentNo drug interventionstreatmentNot Availablecompleted
NCT05942157
Therapeutic Drug Monitoring in Patients With Difficult-to-Treat Gram-Negative Bacterial InfectionsNo drug interventionstreatmentNot Availablerecruiting
NCT00423657
Comparative Study of Ceftaroline vs. Vancomycin Plus Aztreonam in Adult Subjects With Complicated Skin Infectionstreatment3completed
NCT04823026
Host RNA Profiles to Detect Infections in Young InfantsNo drug interventionsNot AvailableNot Availablecompleted
NCT06419426
Prospective Study on Febrile Batteries in Pediatric Oncohaematological Patients (SuBiTo)No drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00000826
Effect of Fluconazole, Clarithromycin, and Rifabutin on the Pharmacokinetics of Sulfamethoxazole-Trimethoprim and Dapsone and Their Hydroxylamine Metabolitestreatment1completed
NCT02074865
Children's Antibiotic Resistant Infections in Low Income CountriesNo drug interventionsNot AvailableNot Availableunknown_status
NCT06025682
Retrospective Observational Study on Infective Complications and Outcome of Patients With ALL Treated With INONo drug interventionsNot AvailableNot Availablerecruiting
NCT04734431
Interest of Eosinopenia to Predict In-hospital Mortality Among Elderly PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT04578873
Phase 1 Oral QPX7831 SAD and MAD in Healthy AdultsNo drug interventionstreatment1completed
NCT02475876
PK of Clindamycin and Trimethoprim-sulfamethoxazole in Infants and Childrenother1completed
NCT04642560
Compliance With AntibIotic TherapY Guidelines in French PICUsNo drug interventionsNot AvailableNot Availablecompleted
NCT05762094
A Retrospective Study on Personalized Dosing Strategy of Patients Treated by Carbapenems: 2018-2021No drug interventionsNot AvailableNot Availablerecruiting
NCT00799591
French Study In ICU Patients Treated With TigecyclineNo drug interventionsNot AvailableNot Availablecompleted
NCT04254991
A Controlled, Blinded Study to Validate the Diagnostic Accuracy and Assess the Clinical Utility of a Host-response Based Diagnostic Tool for Distinguishing Between Bacterial and Viral Etiologies in Pediatric Patients Presenting to the ED With Suspicion of Acute InfectionNo drug interventionsNot AvailableNot Availableunknown_status
NCT04787562
Pharmacokinetics of XNW4107 in Subjects With Various Degrees of Renal Functionbasic_science1completed
NCT00488189
Study Evaluation Tazocin Interventionhealth_services_research4completed
NCT06377592
Development and Accuracy Evaluation of Gram Staining Analysis AINo drug interventionsNot AvailableNot Availablerecruiting
NCT04263792
[18F]Fluoropropyl-Trimethoprim ([18F]F-TMP) PET/CT Imaging to Evaluate Biodistribution and Kinetics in Human SubjectsNo drug interventionsother1recruiting
NCT00318344
Evaluation of Atuna Racemosa ToxicityNo drug interventionstreatment1completed
NCT05072444
Drug-Drug Interaction Study of IV QPX2014 Combined With QPX7728 in Healthy Adult SubjectsNo drug interventionstreatment1completed
NCT00002344
A Study of Azithromycin in HIV-Infected Patientstreatment1completed
NCT00668044
Ciprofloxacin on Burned Patientstreatment3completed
NCT05914467
TDM-optimized Teicoplanin Dosing Versus Standard of Caretreatment4recruiting
NCT01337167
Safety, Tolerability, and Immunogenicity of V419 Given Concomitantly With Prevnar 13™ and RotaTeq™ (V419-005)prevention3completed
NCT00472667
PROcalcitonin Reduce Antibiotic Treatments in Acute-Ill Patients (PRORATA)No drug interventionsdiagnosticNot Availablecompleted
NCT05897801
Distinguishing Bacterial and Viral Infections by MeMed BV® Test to Limit Gut Colonization by MDRONo drug interventionsNot AvailableNot Availablecompleted
NCT03634904
Serum Ceftazidime Concentrations in Hemodialysis PatientsNo drug interventionstreatmentNot Availableunknown_status
NCT03475472
Direct Molecular Characterization of Bacteria From ICU and From the REHABNo drug interventionsNot AvailableNot Availablecompleted
NCT01946568
A Single Dose Study To Investigate The Pharmacokinetics and Safety Of Dalbavancin In Hospitalized Children Aged 3 Months to 11 Years.Not Available1completed
NCT01751269
Safety, Tolerability, Pharmacokinetics of Intravenous RPX7009 in Healthy Adult Subjectstreatment1completed
NCT04841369
Phase III Clinical Trial of a Candidate PCV13 in Healthy People Aged 6 Weeks and Above (PICTPCV13i)prevention3completed
NCT05285046
Phenotypic Profile and Molecular Mechanism of Resistance in Carbapenemase-producing Enterobacterales and Pseudomonas Aeruginosa Isolates From Brazilian Hospitals: Implications for the Introduction of IMIPENEM-RELEBACTAMNo drug interventionsNot AvailableNot Availableunknown_status
NCT03857295
Infections Following NeuroSurgery (INS)No drug interventionsNot AvailableNot Availableunknown_status
NCT02294695
Early Procalcitonin Kinetics During Empirical Antibiotic Therapy in Critically Ill PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT00983255
Ascending Dose Pharmacokinetic (PK) and Absolute Bioavailability (BA)basic_science1completed
NCT00478855
Tazocin Intervention Studyprevention4completed
NCT03696550
A Safety and PK Study of IV Eravacyclinetreatment1completed
NCT00100308
Unfractioned Heparin for Treatment of Sepsistreatment3completed
NCT03234738
A Phase 1 Safety and PK Study of IV TP-271other1completed
NCT00493038
Study to Evaluate the Efficacy and Safety of Moxifloxacin Versus Amoxicillin/Clavulanate in the Treatment of Acute Bacterial Rhinosinusitistreatment4terminated
NCT04801043
To Evaluate the Pharmacokinetics of XNW4107 in Healthy Adult Young Females and in Healthy Adult Elderly Males and Females.basic_science1completed
NCT03761043
Nurse Promotion of IV to PO Antimicrobial ConversionNo drug interventionshealth_services_researchNot Availablecompleted
NCT03992703
Clinical Impact of Rapid AST Directly From Blood CulturesNo drug interventionsNot AvailableNot Availablecompleted
NCT00424190
Comparative Study of Ceftaroline vs. Vancomycin Plus Aztreonam in Adult Subjects With Complicated Skin Infectionstreatment3completed
NCT02688790
Study Evaluate the PK Profile of Dalbavancin in Infants and Neonates Patients With Known or Suspected Bacterial Infectionbasic_science1terminated
NCT05269121
Bacteriophage Therapy in First Time Chronic Prosthetic Joint InfectionsNo drug interventionstreatment1 / 2withdrawn
NCT05088421
A First in Human Study of the Safety and Tolerability of Single and Multiple Doses of BWC0977 in Healthy VolunteersNo drug interventionstreatment1completed
NCT02655302
Study of the Involvement of IL-17 / IL-22 Pathway in Bacterial Exacerbations of COPDNo drug interventionsbasic_scienceNot Availablerecruiting
NCT02852902
Impact of Specific Antimicrobials and MIC Values on the Outcome of Bloodstream Infections Due to ESBL- or Carbapenemase-producing Enterobacterales in Solid Organ Transplantation: an Observational Multinational Study.No drug interventionsNot AvailableNot Availablecompleted
NCT02066402
Efficacy and Safety of Intravenous to Oral 6-Day Tedizolid Phosphate vs. Intravenous to Oral 10-Day Linezolid in Patients With Acute Bacterial Skin and Skin Structure Infection (ABSSSI)treatment3completed
NCT01638702
Study of Complication Rates Associated With PICC for Left vs RightNo drug interventionspreventionNot Availablecompleted
NCT00258102
A Study of the Safety and Effectiveness of Levofloxacin Compared With Lomefloxacin in the Treatment of Complicated Urinary Tract Infectionstreatment3completed
NCT04609384
Nudging Effect of Timer on Surgical RubNo drug interventionsNot AvailableNot Availableunknown_status
NCT03397433
ANti-infective Stewardship Using the Wisca Tool in the Electronic Medical RecordNo drug interventionstreatmentNot Availablecompleted
NCT02500654
Regenerative Surgical Treatment of Peri-implantitisNo drug interventionstreatment4completed
NCT00035854
New Antibiotic to Treat Pediatric Patients With Infections Due to a Specific Bacteria (Vancomycin-Resistant Enterococcus)treatment3completed
NCT04328051
Influence of the Implant-prosthetic Connection in the Marginal Bone Loss and Bacterial LeakageNo drug interventionstreatmentNot Availableunknown_status
NCT02452047
Efficacy and Safety of Imipenem+Cilastatin/Relebactam (MK-7655A) Versus Colistimethate Sodium+Imipenem+Cilastatin in Imipenem-Resistant Bacterial Infection (MK-7655A-013)treatment3completed
NCT06554145
Development and Evaluation of AI Program for Predicting Bacterial Species From Urine Gram Stain SpecimensNo drug interventionsNot AvailableNot Availablerecruiting
NCT00795145
A Study To Assess The Effect Of Linezolid On QTc Intervalbasic_science1completed
NCT01819298
Bacterial Colonization in COPD in View of CAT Under ICS+LABA TherapyNo drug interventionsNot AvailableNot Availablecompleted
NCT03605498
OR PathTrac (Tracking Intra-operative Bacterial Transmission)No drug interventionsNot AvailableNot Availablecompleted
NCT05684705
Study to Investigate the Penetration of Rifabutin Into the Lung After Multiple Intravenous Administrations of BV100treatment1recruiting
NCT01119105
Study Comparing the Safety and Efficacy of Two Doses of BC-3781 vs Vancomycin in Patients With Acute Bacterial Skin and Skin Structure Infection (ABSSSI)treatment2completed
NCT06354205
Comparison of Salivary Procalcitonin (PCT) Levels and Serum PCT LevelsNo drug interventionsdiagnosticNot Availablerecruiting
NCT03738683
Pharmacokinetics of Piperacillin and Tazobactam in Critically Ill PatientsNot AvailableNot Availablecompleted
NCT05584683
A Pharmacokinetic Study of LP-001 in Children With a Bacterial Infectiontreatment1recruiting
NCT00835783
Validation Study of Combined Positron Emission Tomography/Computer Tomography to Diagnose Infection and InflammationNo drug interventionsNot AvailableNot Availableterminated
NCT05259683
Febrile Infant Diagnostic Assessment and Outcome StudyNo drug interventionsNot AvailableNot Availablecompleted
NCT05783661
Trial Comparing Conventional Antibiotic Strategies Versus Regimens Guided by Epidemiological Surveillance in Infected Patients With Cirrhosis (SURVIC_STUDY)No drug interventionstreatment4not_yet_recruiting
NCT00431028
Sub-Tenon's Injection of Triamcinolone and Ciprofloxacin in a Controlled-Release System for Cataract SurgeryNo drug interventionstreatment1 / 2terminated
NCT05840588
Evaluation of the Impact of an Amoxicillin and Amoxicillin/Clavulanic Acid Resistant Probiotic on Key Clinical Outcomes in Children Treated With Amoxicillin or Amoxicillin/Clavulanic AcidNo drug interventionstreatmentNot Availablerecruiting
NCT01689207
To Investigate the Safety and Tolerability of Aztreonam-Avibactam (ATM-AVI)basic_science1completed
NCT06404307
Self-administration in Outpatient Parenteral Antimicrobial Therapy ServiceNo drug interventionshealth_services_researchNot Availablenot_yet_recruiting
NCT05645107
A Study to Evaluate Efficacy, Safety, and Pharmacokinetics of XEMBIFY® Plus Standard Medical Treatment (SMT) Compared to Placebo Plus SMT to Prevent Infections in Participants With Hypogammaglobulinemia and Recurrent or Severe Infections Associated With B-cell Chronic Lymphocytic Leukemiatreatment3recruiting
NCT02146209
Study to Determine the Equivalence of Three Products Containing Metronidazole Benzoate.treatment1completed
NCT00998309
Zithromax-SR 2g, Special Investigation (Regulatory Post Marketing Commitment Plan)Not AvailableNot Availablecompleted
NCT03896685
Evaluating Newly Approved Drugs in Combination Regimens for Multidrug-Resistant TB With Fluoroquinolone Resistance (endTB-Q)treatment3active_not_recruiting
NCT01608815
Study of a Single Dose of SP093 Typhoid Vi Polysaccharide Vaccine in Japanese Subjectsprevention3completed
NCT00670215
BAYQ3939, 1000 mg Tablet in Transrectal Needle Biopsies of the Prostate (TRNBP) - Infection Prophylaxisprevention3completed
NCT06046937
Monolaurin Ointment Versus Mupirocin Ointmenttreatment0completed
NCT01587937
Hospital Wide Roll-Out of Antimicrobial StewardshipNo drug interventionshealth_services_researchNot Availablecompleted
NCT01340937
A Study of V419 Given Concomitantly With Prevnar 13™ and RotaTeq™ (V419-006)prevention3completed
NCT03919032
Bacterial Infections in Patients With Cirrhosis in Argentina: Clinical and Microbiological CharacteristicsNo drug interventionsNot AvailableNot Availablecompleted
NCT00945152
Effects of MRSA Bactericidal Gel To Promote Healing and Eliminate MRSA in cSSTI Vancogel(TM)treatment2recruiting
NCT02993575
Pharmacokinetics of Flucloxacillin Given by Continuous or Intermittent Infusion to ICU PatientsNot AvailableNot Availablecompleted
NCT01159470
The Rate of C-reactive Protein (CRP) Increase as a Marker for Bacterial Infections in ChildrenNo drug interventionsNot AvailableNot Availableunknown_status
NCT00366249
Study Evaluating the Safety and Efficacy of a Once-daily Dose of Tigecycline vs Ertapenem in Diabetic Foot Infections (DFI) With a Substudy in Patients With Diabetic Foot Infections Complicated by Osteomyelitis.treatment3completed
NCT00288418
Safety and Efficacy Study of Angiotech Central Venous Catheter to Prevent Bacterial Catheter ColonizationNo drug interventionsprevention3completed
NCT05684718
To Evaluate the Effect of Multiple Doses of Itraconazole on the Pharmacokinetics of BV100treatment1completed
NCT02426918
Study of Debio 1450 for Bacterial Skin Infectionstreatment2completed
NCT02269319
MRX-I Versus Linezolid for the Treatment of Acute Bacterial Skin and Skin Structure Infectiontreatment2completed
NCT02134834
A Phase I Study to Assess Safety, Tolerability and Pharmacokinetics of OP0595No drug interventionstreatment1completed
NCT00515034
A Safety and Tolerability Study of Doripenem in Patients With Abdominal Infections or Pneumoniatreatment2completed
NCT01932034
Prospective Study to Optimize Vancomycin Dosing in Children and Adults Using Computer SoftwareNo drug interventionsNot AvailableNot Availablecompleted
NCT02848534
The Value of the Neutrophil to Lymphocyte Ratio in the Diagnosis of Bacterial InfectionsNo drug interventionsNot AvailableNot Availablecompleted
NCT01058824
Relative Bioavailability Study Of Two Lincomycin Hydrochloride Hard Gelatinous CapsuleNot Available1completed
NCT04688216
Developing a Risk Assessment System of Multidrug-resistant Organisms InfectionNo drug interventionsNot AvailableNot Availablecompleted
NCT01480258
Safety, Tolerability, and Immunogenicity of V419 in Healthy Infants When Given at 2, 4, and 11 to 12 Months (V419-008)prevention3completed
NCT00353158
A Pilot of Pediatric/Adult Study of Gene Expression Profiling and Clinical Characterization of Phototoxicitybasic_science1completed
NCT00449735
Quinolone Resistance in Bloodstream Isolates of Escherichia ColiNo drug interventionsNot AvailableNot Availablecompleted
NCT04802863
Intrapulmonary Pharmacokinetics of XNW4107, Imipenem and Cilastatin in Healthy Subjectsbasic_science1completed
NCT00347386
Therapeutic Zinc in Infant Bacterial Illnesstreatment2 / 3completed
NCT01341639
Safety, Tolerability, and Immunogenicity of V419 in Healthy Infants When Given at 2, 3, 4 and 12 Months (V419-007)prevention3completed
NCT00493922
Trial of Rapid Diagnostic Tests in Rural GhanaNo drug interventionsdiagnostic4completed
NCT05641025
Prediction of Multidrug-resistant Bacterial Infection in Patients With CirrhosisNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT01744730
Safety and Pharmacokinetics of Clindamycin in Pediatric Subjects With BMI ≥ 85th Percentilebasic_science1completed
NCT02306330
MALDITOF Versus Routine Clinical Microbiology for Identifying Pathogens; a Randomized Diagnostic TrialNo drug interventionsdiagnosticNot Availablecompleted
NCT00965848
A Safety and Efficacy Study of Doripenem in Participants With Nosocomial Pneumonia, Complicated Intra-Abdominal Infections and Urinary Tract Infectionstreatment4completed
NCT03933748
Therapeutic Drug Monitoring of Teicoplanin in ChildrenNot AvailableNot Availablerecruiting
NCT01381848
A Study of Doripenem in Infants Less Than 12 Weeks of AgeNot Available1completed
NCT05998226
VAT-2: Evaluation of a Virtual Antimicrobial Stewardship Team (VAT) on Antibiotic Prescriptions in Nursing HomesNo drug interventionshealth_services_researchNot Availablerecruiting
NCT02361866
To Evaluate the Effectiveness(Immunogeneicity) and Safety of 'GC1107' Administered Intramuscularly in Healthy AdultsNo drug interventionsprevention3completed
NCT03767374
Risk-factors for Multidrug-resistant Bacteria Colonization Among Patients at High Risk of STIsNo drug interventionsNot AvailableNot Availableunknown_status
NCT05210920
RBG: Regular, Bare, Gel: Does Type of Nail Polish Affect Bacterial Counts After Surgical Scrubbing?No drug interventionspreventionNot Availablecompleted
NCT05942820
The Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of BWC0977 in Healthy Adult VolunteersNo drug interventionstreatment1terminated
NCT04864873
Evaluation of a mNGS Workflow for Infection Diagnosis Using Oxford Nanopore Sequencing.No drug interventionsdiagnosticNot Availableunknown_status
NCT03646227
Multi-Drug Resistant Organism NetworkNo drug interventionsNot AvailableNot Availablecompleted
NCT04783727
PredictEndTB Signature for Individualizing Treatment in Multidrug-Resistant TuberculosisNo drug interventionstreatmentNot Availableterminated
NCT02877927
Oral Omadacycline vs. Oral Linezolid for the Treatment of ABSSSItreatment3completed
NCT00410527
Effectiveness of Short-Course Versus Standard Antibiotic Therapy in ICU Patientstreatment4completed
NCT03931876
A Single Ascending Dose Study of AV-006 in Healthy SubjectsNo drug interventionstreatment1unknown_status
NCT04806776
Frequence of Dressing Change and Bacterial Colonization in Pediatric Intensive Care UnitNo drug interventionspreventionNot Availablecompleted
NCT04358991
Pharmacokinetics of Ceftazidime-avibactam Among Critically-ill Patients Receiving CVVHDFNot AvailableNot Availablecompleted
NCT03204591
Bacterial Infections in Cirrhotic Patients With Acute Severe Liver InjuryNo drug interventionsNot AvailableNot Availableunknown_status
NCT03925480
Preventing Young Infant Infections Using Azithromycin in Labour (PreYIAL) Trialprevention3completed
NCT00575380
Study of AzaSite Versus Vigamox Concentrations in the Conjunctiva and Aqueous Humor in Subjects Undergoing Routine Cataract Surgerysupportive_care4completed
NCT02378480
Omadacycline Versus Linezolid for the Treatment of ABSSSI (EudraCT #2013-003644-23)treatment3completed
NCT03271580
Biofilm Modified Macrophage Phenotype and Function in Diabetic Wound HealingNo drug interventionsNot AvailableNot Availableterminated
NCT06211829
An Evaluation of a Antimicrobial Stewardship Recommendation Bundle for Staphylococcus Aureus Bloodstream InfectionsNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT03939429
Phase 1 Study of Oral QPX2015 in Healthy Adult SubjectsNo drug interventionstreatment1completed
NCT04196192
Febrile Infants - Diagnostic Assessment and OutcomeNo drug interventionsNot AvailableNot Availablecompleted
NCT04096092
Pharmacokinetics of Teicoplanin in Intensive Care and Haematology PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT03780140
Expanded Access to Cefiderocol for the Intravenous Treatment of Severe Gram Negative Bacterial InfectionsNot AvailableNot Availableapproved_for_marketing
NCT00575367
Study of AzaSite Versus Vigamox in the Tears of Healthy Volunteerssupportive_care4completed
NCT03696901
Xydalba Utilization Registry in GermanyNot AvailableNot Availableterminated
NCT04226001
Impact of a Carrier (Infection, Colonization) of Highly Bacteria Resistance on the Patient's Quality of Life Hospital EnvironmentNo drug interventionsNot AvailableNot Availablewithdrawn
NCT01412801
Magnitude of the Antibody Response to and Safety of a GBS Trivalent Vaccine in HIV Positive and HIV Negative Pregnant Women and Their OffspringsNo drug interventionsprevention2completed
NCT04100772
Phase I Clinical Trial of a Candidate PCV13 in Healthy People Aged 6 Weeks and Aboveprevention1completed
NCT03192072
A Rapid Test for Acute Respiratory IllnessNo drug interventionsNot AvailableNot Availablecompleted
NCT04482569
Study to Evaluate Safety, Tolerability, and Pharmacokinetics of XNW4107 Alone or in Combination With Imipenem/CilastatinNo drug interventionsbasic_science1completed
NCT01528969
Effect of Xylitol on Oral Microbiota in ChildrenNo drug interventionstreatment1 / 2completed
NCT02837081
Preauthorization Versus Prospective Audit in Antimicrobial Stewardship ProgramNo drug interventionsNot AvailableNot Availableunknown_status
NCT00190281
Contrast-Enhanced US of Spleen, Liver and KidneyNo drug interventionsNot AvailableNot Availableunknown_status
NCT02527681
Pharmacokinetics and Safety of Ceftobiprole in Neonates and Infants up to 3 Months Treated With Systemic Antibioticstreatment1terminated
NCT05590195
Effect of PreforPro® on Urinary and Vaginal HealthNo drug interventionstreatment3not_yet_recruiting
NCT04517695
Blood Volume Assessment in COVID-19 and Bacterial SepsisNo drug interventionsNot AvailableNot Availablecompleted
NCT02541695
Characterization of Resistance Against Live-attenuated Diarrhoeagenic E. Colibasic_scienceNot Availablecompleted
NCT05614895
A Study to Investigate the Pharmacokinetics of RO7223280 in Critically Ill Participants With Bacterial InfectionsNo drug interventionstreatment1completed
NCT04502914
The Study on Bacterial Load Following Open-to-air Management in Burn Patients.No drug interventionstreatmentNot Availablewithdrawn
NCT04808414
SAD/MAD Safety and PK Study of QPX9003 (Novel Polymyxin) in Normal Healthy VolunteersNo drug interventionstreatment1completed
NCT01966055
Pharmacokinetics and Safety of Solithromycin Capsules in Adolescentstreatment1completed
NCT00216450
Study of the Safety and Effectiveness of Rabeprazole in Treatment of Helicobacter Pylori Infection in Adults.treatment4completed
NCT00037050
Antibiotic Treatment for Infections of Short Term In-dwelling Vascular Catheters Due to Gram Positive Bacteriatreatment3completed
NCT05226923
Study of the Safety and Pharmacokinetics of KSP-1007 Alone and Coadministered With Meropenem in Healthy Subjectsother1completed
NCT05586438
Pharmacokinetics of Colistin in Critically-ill Patients With AKI Who Receive SLEDprevention4completed
NCT03233438
Development of a New Critical Pathway for Treatment of Acute Bacterial Skin and Skin Structure Infections (ABSSSI)treatment4completed
NCT03617042
Study Evaluate the PK Profile of Dalbavancin in Infants and Neonates Patients With Known or Suspected Bacterial Infectionbasic_science1recruiting
NCT00189384
Efficacy Study of Community-Based Treatment of Serious Bacterial Infections in Young Infantstreatment3unknown_status
NCT02268279
Pharmacokinetics and Safety of Solithromycin in Adolescents and Childrentreatment1completed
NCT02375477
Improved Adherence to C. Difficile Isolation Protocols Through Improved Education MethodsNo drug interventionshealth_services_researchNot Availablecompleted
NCT01156077
Pharmacokinetic (PK) Study of Oral and IV TR-701 FA in Adolescent Patientsbasic_science1completed
NCT00407147
Procalcitonin Level to Discontinue Antibiotics on ICU Patients With no Obvious Site of InfectionNo drug interventionstreatment4terminated
NCT01271998
Pulmonary Disposition of TR-700 Following Once-Daily Oral 200 mgbasic_science1completed
NCT01485705
Retrospective Examination of Initial Care of Severe Bacterial Infections of the ChildNo drug interventionshealth_services_researchNot Availablecompleted
NCT00765778
Mastering Hospital Antimicrobial Resistance and Its Spread Into the CommunityNo drug interventionsNot AvailableNot Availableunknown_status
NCT01371656
Levofloxacin in Preventing Infection in Young Patients With Acute Leukemia Receiving Chemotherapy or Undergoing Stem Cell Transplantationsupportive_care3completed
NCT02914132
Safety Evaluation of Seraph® 100 to Reduce Bacteremia in Patients on HemodialysisNo drug interventionstreatmentNot Availablecompleted
NCT00633152
Efficacy and Safety of Ceftaroline Versus Linezolid in Subjects With Complicated Skin and Skin Structure Infectionstreatment2completed
NCT01817075
Chlorhexidine Gluconate Cleansing in Preventing Central Line Associated Bloodstream Infection and Acquisition of Multi-drug Resistant Organisms in Younger Patients With Cancer or Undergoing Donor Stem Cell TransplantNo drug interventionssupportive_care3completed
NCT00307099
Comparative Antibiotic Therapy for Subjects With Pulmonary Infiltrates in the ICUtreatment3terminated
NCT01289249
Meropenem Plasma Concentration Measurements at the Pediatric Medical Ward, Oslo University Hospital, RikshospitaletNo drug interventionsNot AvailableNot Availablecompleted
NCT01800396
Milk Ingredients and Resistance Against E-coli-induced GastroEnteritis (MIRAGE)No drug interventionspreventionNot Availablecompleted
NCT01892358
Preventing Bacterial and Viral Infections Among Injection Drug UsersNo drug interventionspreventionNot Availablecompleted
NCT00389558
Antiseptic Use and Dressing ApplicationNo drug interventionsprevention4completed
NCT02544230
Granulocyte Transfusions in Hematological Patients With Febrile NeutropeniaNo drug interventionsNot AvailableNot Availablecompleted
NCT00692848
Impact of Procalcitonin on the Management of Children Aged 1 to 36 Month Presenting With a Fever Without a SourceNo drug interventionsdiagnosticNot Availablecompleted
NCT05645757
Safety Study of Intravenous Ertapenem in Combination With Zidebactam (WCK 6777)treatment1completed
NCT04479657
Qingfei Granule for the Treatment of the Pediatric Acute Upper Respiratory Tract Infection With Bacterial Infectiontreatment0recruiting
NCT01709266
The Effect of Probiotics on E. Coli-induced GastroenteritisNo drug interventionspreventionNot Availablecompleted
NCT02794831
Exposure to NSAIDs (Non Steroidal Anti-Inflammatory Drugs) and Severity of Community-acquired Bacterial InfectionsNo drug interventionsNot AvailableNot Availablecompleted
NCT03299894
Impact of qSOFA Calculation on the Timing of Antimicrobial Therapy in the Emergency DepartmentNo drug interventionsdiagnosticNot Availablecompleted
NCT00004829
Phase III Randomized Study of the Inhalation of Tobramycin in Patients With Cystic Fibrosistreatment3completed
NCT01012089
Study of the Pharmacokinetics of Daptomycin in Children With Renal DiseaseotherNot Availablecompleted
NCT01446289
Immune Response Induced by a Vaccine Against Group B Streptococcus and Safety in Pregnant Women and Their OffspringsNo drug interventionsprevention2completed
NCT00271440
Effect of Chlorhexidine Cleansing on Skin Flora of Newborns in NepalNo drug interventionstreatment1 / 2completed
NCT01611740
Contribution of Real Time Analyses of CARdio-RESpiratory Signals to the Diagnosis of Infection in PREterM InfantsNo drug interventionsNot AvailableNot Availablecompleted
NCT04550767
: Bacterial Infections in Injecting Drug UsersNo drug interventionsNot AvailableNot Availablecompleted
NCT00430469
Safety of hLF1-11 for the Treatment of Infectious Complications Among HSCT Recipientsprevention1 / 2withdrawn
NCT01059890
Cerebral Antibiotics Distribution After Acute Brain InjuryNot Available1completed
NCT00760279
An Open Label Evaluation of the Pharmacokinetics and Safety of Single Dose Intravenous Azithromycin in Preterm Neonatestreatment1completed
NCT02753387
Effect of Oral Preparation on Bacterial Colonization of the Pharyngeal Mucosa in Surgery of Head and Neck Cancerprevention3completed
NCT03369951
Minocycline Pharmacokinetics (ACUMIN)treatment4completed
NCT01244698
Postoperative Antibiotic Requirements Following Immediate Breast Reconstructiontreatment4completed
NCT05590728
Safety of Intravenous Apramycin in Adultstreatment1completed
NCT02052388
Efficacy and Safety Study of Brilacidin to Treat Serious Skin Infectionstreatment2completed
NCT00800488
Procalcitonin for Predicting Serious Bacterial Infection in Infants Less Than 3 MonthsNo drug interventionsNot AvailableNot Availablecompleted
NCT02533609
Elimination of Antibiotics During Citrate-anticoagulated Continuous-veno-venous-haemodialysisNo drug interventionsNot AvailableNot Availableunknown_status
NCT00680485
Evaluation of the Safety, Tolerability and Pharmacokinetics of Repeat Oral Doses of GSK580416treatment1terminated
NCT01803100
Characterizing and Comparing the Profile of Microorganisms From Specific Body Sites and Environmental Surfaces in Newly Disinfected Patient RoomsNo drug interventionsNot AvailableNot Availablecompleted
NCT02294175
Larval Debridement Therapy Versus Sharp Debridement to Remove BiofilmNo drug interventionstreatmentNot Availablecompleted
NCT01173575
Assessment of the Efficacy of FOSFOMYCIN in Patients With Bacterial InfectionNo drug interventionsNot AvailableNot Availablecompleted
NCT01225042
The Effect of Probiotics on E. Coli GastroenteritisNo drug interventionspreventionNot Availablecompleted
NCT00915213
Incidence of Antibiotic Resistant E.Coli in Patients Undergoing Repeat Prostate BiopsyNo drug interventionsNot AvailableNot Availablecompleted
NCT02598141
Grinding Versus Standard Methods for the Treatment of Per-operative Bacteriological Samples Associated With Osteo-articular SepsisNo drug interventionsdiagnosticNot Availablecompleted
NCT00176124
Leukocyte Depletion of Autologous Whole BloodNo drug interventionstreatment4completed
NCT02311816
Increase in Procalcitonin Kinetics May be a Good Indicator of Starting Empirical Antibiotic Treatment in Critically Ill PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT00254696
Study Evaluating Antibiotic Utilization Measures and Control of Extended-Spectrum-Lactamases (ESBLs)No drug interventionsprevention4completed
NCT02931526
Study of Tigecycline Pharmacokinetics in Patients Undergoing Continuous Renal Replacement Therapy(CRRT)Not AvailableNot Availableunknown_status
NCT01250574
Neutrophil CD64 and Procalcitonin as Novel Biomarkers for Postoperative InfectionsNo drug interventionsNot AvailableNot Availablecompleted
NCT00271531
Bacterial Pulmonary Infection in PICUNo drug interventionsNot AvailableNot Availablecompleted
NCT03910673
Intravenous Fosfomycin Pharmacokinetics Studytreatment1completed
NCT00275327
Mechanisms of Resistance and Molecular Epidemiology of Commonly Encountered Multi-Resistant BacteriaNo drug interventionsNot AvailableNot Availablecompleted
NCT00198627
Etiology, Prevention and Treatment of Neonatal Infections in the CommunityNo drug interventionstreatmentNot Availablecompleted
NCT02436876
Study to Assess Safety and Clinical Activity of Local MBN-101 in Treatment of Infected Bone Sitestreatment2completed
NCT03978091
A Trial to Evaluate the Pharmacokinetics and Safety of AVYCAZ(R) in Combination With Aztreonamtreatment1 / 2completed
NCT00939562
Bioequivalence Between Two Tablet Formulations Of Doxycycline Carragenatebasic_science4completed
NCT04079790
Pharmacokinetics of Gepotidacin Tablets in Adults and Adolescents Subjectstreatment1completed
NCT01934205
To Evaluate Plasma and Pulmonary Pharmacokinetics of GSK2140944treatment1completed
NCT02045797
Dose-Ranging Study of GSK2140944 in the Treatment of Subjects With Suspected or Confirmed Gram-Positive Acute Bacterial Skin and Skin Structure Infectionstreatment2completed
NCT01610388
A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Oral and Intravenous GSK1322322 in Healthy SubjectsNo drug interventionsother1completed
NCT01953809
A Pharmacokinetics, Pharmacodynamics, and Safety Study of an Oral Contraceptive Containing Norethindrone and Ethinyl Estradiol When Co-administered With GSK1322322 in Healthy Adult Womentreatment1withdrawn
NCT01262885
A Randomized, Single Blind, Placebo Controlled Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Single Oral Doses and Repeat Escalating Oral Doses of GSK2251052 in Healthy Adult Subjectstreatment1completed
NCT03568942
Pharmacokinetic Study of Oral Gepotidacin (GSK2140944) in Subjects With Uncomplicated Urinary Tract Infection (Acute Cystitis)treatment2completed
NCT01803399
A Study to Evaluate the Effect of GSK1322322 on Cardiac Conduction as Assessed by 12-lead Electrocardiogram in Healthy Volunteerstreatment1withdrawn
NCT01132417
In Vitro Activity of Tigecycline Among Key Bacterial Pathogens Exhibiting Multidrug ResistanceNot AvailableNot Availablesuspended
NCT03562117
Pharmacokinetics (PK) Study of Gepotidacin (GSK2140944) in Adult Subjects With Varying Degrees of Hepatic Impairment and in Matched Control Subjects With Normal Hepatic Functiontreatment1completed
NCT04620486
Effect of BPA on Anchor Antibiotic Continuity in the ED: Randomized Controlled TrialNo drug interventionstreatmentNot Availablecompleted
NCT04310722
Gram-negative Bacilli and MRSA Screening in ICU in ChinaNo drug interventionsNot AvailableNot Availableunknown_status
NCT05340257
A Pharmacokinetics and Safety Study of Augmentin ES-600 in Children With CAP and ABRStreatment2not_yet_recruiting
NCT04493931
Drug-drug Interaction Study of Gepotidacintreatment1completed
NCT01431989
Amoxicillin Bioequivalence Study Brazil - Fastother1completed
NCT03408392
Bioequivalence Study Between SKF101804 Cefixime 200 Milligram (mg)/5 Milliliter (mL) Suspension Versus Cefixime 200 mg/5 mL Suspension Reference Product in Healthy Adult Subjects Under Fasting ConditionsNo drug interventionstreatment1completed
NCT03557840
Plasma Protein Binding and PK/PD of Total and Unbound Temocillin Non-ICU PatientsotherNot Availableunknown_status
NCT00828867
Single Dose Escalation First Time in Human PK StudyNo drug interventionstreatment1completed
NCT06451172
Novel Antisense Oligonucleotide Eye Drops for Treating Antibiotic-Resistant Bacterial KeratitisNo drug interventionstreatment0recruiting
NCT01587768
WEUKBRE5555: IMI PROTECT(Work Package 2): Liver Injury & AntibioticsNo drug interventionsNot AvailableNot Availablecompleted
NCT02729038
Pharmacokinetic Study of Gepotidacin in Subjects With Varying Degrees of Renal Impairment and in Subjects With Normal Renal Functiontreatment1completed
NCT02177721
Clinical Benefit, Safety and PK of Raxibacumab in Subjects Exposed to Bacillus Anthracistreatment4not_yet_recruiting
NCT01648179
A Study to Assess the Relative Bioavailability of Three Formulations and Food Effect on GSK1322322 in Healthy Subjectstreatment1completed
NCT03329547
A Bioequivalence Study of SKF101804 Cefixime Versus Cefixime Reference Formulation in Healthy Adults Under Fasting Conditionstreatment1withdrawn
NCT02292498
Thermal Imaging to Diagnose and Monitor Suspected Bacterial InfectionsNo drug interventionsdevice_feasibilityNot Availablecompleted
NCT01818011
A Three-part Study to Determine the Safety, Tolerability and Pharmacokinetics of GSK1322322 in Healthy Volunteers and Healthy Male Japanese Subjectstreatment1terminated
NCT00924911
Relative Bioavailability Study in Healthy Subjectstreatment1completed
NCT00358371
Bioavailability Of Flucloxacillin Capsules (250 mg and 500 mg)treatment1completed
NCT00259909
Observational Study Of An Electronic Questionnaire In Patients With Chronic Obstructive Pulmonary Disease (COPD)No drug interventionsNot AvailableNot Availablecompleted
NCT02045849
Relative Bioavailability, Safety, Tolerability, Pharmacokinetics (PK) and Food Effect Study of GSK2140944 in Healthy Subjectstreatment1completed
NCT05752019
TAAI Erasmus Research Initiative to Fight CF: Monitoring Inflammation in CF Lung Disease Into a New EraNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT00427141
A Three-Part Study Of GSK580416 In Healthy SubjectsNo drug interventionstreatment1completed
NCT06427317
Routinely Collected Clinical Data and Evaluation of Antimicrobial Target AttainmentNo drug interventionsNot AvailableNot Availablerecruiting
NCT02751424
A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Ascending Intravenous Single Dose and Repeat Dose of GSK3342830No drug interventionstreatment1terminated
NCT00896558
A Repeat Dose Escalation Study to Investigate the Safety, Tolerability and Pharmacokinetics of GSK1322322 in Healthy SubjectsNo drug interventionstreatment1completed
NCT02853435
To Assess Bioavailability, Food Effect and Pharmacokinetics of Gepotidacin Tablets: A Phase I, Single-Dose, 2 Part Study in Healthy Subjects.treatment1completed
NCT03150082
Bioequivalence Study Between GR37547 500 Milligrams (mg) Tablet Versus Ciprofloxacin 500 mg Tablet Reference Product in Healthy Adult Subjectstreatment1completed
NCT00517673
To Evaluate Safety, Tolerability, Pharmacokinetics, And Food Effect Of Single Doses Of GSK945237 In Healthy SubjectsNot Available1completed
NCT00539994
Retapamulin Ointment in Healthy Adults Nasally Colonized With Staphylococcus Aureustreatment2completed
NCT01663389
A Study to Investigate the Recovery, Excretion, and Pharmacokinetics of 14C -GSK1322322 After an Intravenous and an Oral Dosetreatment1completed
NCT06440304
Therapeutic Options for CRABtreatment4not_yet_recruiting
NCT02778672
Thermal Imaging of the Lung on a Smartphone to Differentiate Bacterial From Non Bacterial Causes of PneumoniaNo drug interventionsNot AvailableNot Availablecompleted
NCT01039610
A Single Center Four Part Study in Healthy Adult Subjects to Evaluate: the Safety, Tolerability and Pharmacokinetics of a Single Oral Dose and Repeat Escalating Oral Doses of GSK945237; the Effect of Linezolid on Hematology Safety Parameters; and the Effects of GSK945237 and Moxifloxacin on QTc.treatment1withdrawn
NCT02339155
Effect of Raxibacumab on Immunogenicity of Anthrax Vaccine Adsorbedtreatment4completed
NCT05870150
Challenge Non-Typhoidal Salmonella (CHANTS) StudyNo drug interventionsbasic_scienceNot Availablerecruiting
NCT03925402
Ertapenem for Initial Empirical Treatment of Third Generation Cephalosporin Resistant Enterobacteriaceae BacteremiaNot AvailableNot Availablecompleted
NCT05950984
Medical Device (MD) Derived Pharmacokinetic (PK) Parameters for Vancomycin (MD-PK)No drug interventionsNot AvailableNot Availablerecruiting
NCT05333133
High Calorie Formula Intervention on Weight, Length Increment, Total Lymphocyte Counts, TNF-alpha and IGF-1 in Failure to Thrive ChildrenNo drug interventionssupportive_careNot Availablecompleted
NCT04280354
Molecular Biomarkers for SepsisNo drug interventionsNot AvailableNot Availableterminated
NCT05686577
How to Reduce Unnecessary Blood Cultures: Construction and Validation of a Predictive Score for Blood Culture Positivity in Intensive CareNo drug interventionsNot AvailableNot Availablecompleted
NCT03290105
Microbial and Pharmacological Assessment of ChlorhexidineNo drug interventionsNot AvailableNot Availablecompleted
NCT04589897
Manuka Honey Sinus Rinse StudyNo drug interventionsbasic_scienceNot Availablecompleted
NCT03903783
Impact of Cefotaxime and Ceftriaxone on the Emergence and Carrying of Multidrug-Resistant BacteriaNo drug interventionsotherNot Availablecompleted
NCT03252028
Rapid Test for Detection of the Focus of Infection in Post Neurosurgical Patients.No drug interventionsNot AvailableNot Availableunknown_status
NCT03163628
biomArkers to differeNtiate bacTerial From vIral iNfEctionsNo drug interventionsdiagnosticNot Availablecompleted
NCT03088111
An Open Label Field Study of Anthim (Obiltoxaximab) in Subjects Exposed to B. Anthracistreatment4not_yet_recruiting
NCT05027893
Complications After Lower Third Molar SurgerypreventionNot Availableunknown_status
NCT03816956
Adjunctive Therapy to Antibiotics in the Treatment of S. Aureus Ventilator-Associated Pneumonia With AR-301treatment3completed
NCT04282785
Point-of-care Monitoring of Antibiotic Concentration in Blood With UV-VIS Absorption SpectroscopyNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04555252
Colonization of Bile Ducts and Infectious Complications in Cephalic DuodenopancreatectomyNo drug interventionsNot AvailableNot Availablecompleted
NCT04894500
ICIS in Burn Patients Compared to Other Inflammatory MarkersNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT04664075
Predicting Severity and Disease Progression in Influenza-like Illness (Including COVID-19)No drug interventionsNot AvailableNot Availableterminated
NCT06220370
PATH Study: People With Injecting Related Infections: Assessing Treatment Outcomes for Those Who Are Hospitalised.No drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT05993442
Optimising Kangaroo Care to Reduce Neonatal Severe Infection/Sepsis and Resistant Bacterial Colonisation Among High-risk Infants in Neonatal Intensive Care.No drug interventionssupportive_careNot Availablenot_yet_recruiting
NCT05960006
A Study to Determine Pharmacokinetic Changes of Ceftriaxone in Patients With Liver CirrhosisNo drug interventionsNot AvailableNot Availablerecruiting
NCT05307406
A First-in-Human Study With XAB05 in Healthy SubjectsNo drug interventionstreatment1completed
NCT03244917
Trial to Reduce Antimicrobial Use In Nursing Home Residents With Alzheimer's Disease and Other DementiasNo drug interventionshealth_services_researchNot Availablecompleted
NCT03009734
Evaluation of ATx201 as a Topical Antibiotic AgentNo drug interventionstreatment1 / 2completed
NCT04608916
Efficacy of Surgical Diathermy in Eradicating Cutibacterium Acnes From Surgical Skin Incision During Shoulder ArthroplastyNo drug interventionspreventionNot Availablecompleted
NCT05904535
Novel Diagnostic Methods to Identify External Ventricular Drain Associated InfectionsNo drug interventionsNot AvailableNot Availablerecruiting
NCT06126263
Adjunctive Clindamycin Versus Linezolid for β-lactam Treated Patients With Invasive Group A Streptococcal InfectionsNot AvailableNot Availableactive_not_recruiting
NCT03172039
Antimicrobial Use and Stewardship in an Outpatient Hemodialysis UnitNo drug interventionsNot AvailableNot Availablecompleted
NCT06190548
Clinical Outcomes of Hypervirulent Carbapenem-resistant Klebsiella Pneumoniae InfectionNo drug interventionsNot AvailableNot Availablecompleted
NCT04067557
Diagnosis of Bacterial Vaginosis Comparing Modified Hay/Ison With Molecular DiagnosisNo drug interventionsNot AvailableNot Availablecompleted
NCT04440631
Gut Microbiome of Patients Undergoing Antibiotic Therapy for Orthopedic Device-related InfectionNo drug interventionsNot AvailableNot Availablecompleted
NCT05302531
Absorption of Antibiotics With High Oral Bioavailability in Short-bowel Syndrometreatment1recruiting
NCT04297176
Economic Evaluation of Vancomycin Therapeutic Drug Monitoring MethodstreatmentNot Availablecompleted
NCT05153694
Infectious Complications After Cystectomy: A Prospective Observational StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT06018792
Molecular Culture for the Diagnosis of Pediatric SepsisNo drug interventionsNot AvailableNot Availablerecruiting
NCT04287504
Point-of-care Tests for Bacterial Vaginosis and CandidosisNo drug interventionsNot AvailableNot Availableunknown_status
NCT03339869
Therapeutic Drug Monitoring of Anti-infectious Drugs in Intensive Care UnitNo drug interventionsotherNot Availableunknown_status
NCT03133312
Chlorhexidine Gluconate Versus Povidone-Iodine as Vaginal Preparation Antiseptics Prior to Cesarean Deliverytreatment4completed
NCT04404855
Antibiotic Selection Using Next Generation Sequencing vs Urine CultureNo drug interventionspreventionNot Availablecompleted
NCT03688321
Probiotic on Prevention of GBS Vaginal Infection During PregnancyNo drug interventionspreventionNot Availablecompleted
NCT05971979
Therapeutic Drug Monitoring - Targeting IMproved EffectivenessNo drug interventionsNot AvailableNot Availablerecruiting
NCT05914779
Impact of Early Antibiotics on Non-Traumatic Out of Hospital Cardiac Arrest (OHCA)No drug interventionspreventionNot Availablerecruiting
NCT06283433
A Dried Blood Spot Sampling Method for Vancomycin and Creatinine Monitoring for OPATNo drug interventionshealth_services_researchNot Availablerecruiting
NCT02992951
DACC in the REduction of Surgical Site INfectionNo drug interventionstreatmentNot Availablerecruiting
NCT03985605
Therapeutic Drug Monitoring of Antiinfectives for Patients With Severe Illness = TAPSINo drug interventionsNot AvailableNot Availablecompleted
NCT06379061
Access MeMed BV Assay Clinical Study Collection Protocol - Infectious Adult and Pediatric CohortsNo drug interventionsNot AvailableNot Availablerecruiting
NCT05542771
External Validation of the Beta-lactam Target Non-attainment (BATMAN) Risk Score in Adult ICU Patients: a Diagnostic Multivariate Predictive Risk ModelNo drug interventionsNot AvailableNot Availablerecruiting
NCT05361278
Evaluation of Gel and Solution of Chlorhexidine in Disinfection Root Canals of Primary Anterior Teeth.No drug interventionstreatmentNot Availablecompleted
NCT03633188
Stool Biobanking and Impact of Antimicrobials on the Gut Microbiota in Patients With Bone and Joint InfectionNo drug interventionsbasic_scienceNot Availableterminated
NCT01904188
Clinical Microbial Species & Antibiotic Resistance ID in ED Patients Presenting With Infection - is Rapid ID Possible & Accurate?No drug interventionsNot AvailableNot Availablerecruiting
NCT05082909
Addition of Probenecid to Penicillin-V Therapytreatment1 / 2unknown_status
NCT05150015
ElastoMeric Infusion Pumps for Hospital AntibioTICsNo drug interventionsdevice_feasibilityNot Availableactive_not_recruiting
NCT04447937
Immunodeficiency in MSNo drug interventionsNot AvailableNot Availableunknown_status
NCT05223400
Drug Use Evaluation of Clindamycin in Critical Care Units in Alexandria Main University HospitalNot AvailableNot Availablecompleted
NCT06126900
Smartphone App-assisted Short-term Antibiotic TherapyNo drug interventionshealth_services_researchNot Availablerecruiting
NCT04809259
Ambulatory Administration of Meropenem With Elastomeric Pumps and an Isothermal PouchNo drug interventionstreatment0not_yet_recruiting
NCT04800575
Comparison of Sterile Gauze and Semi-permeable Film Dressing for Hemodialysis Central Venous CatheterNo drug interventionspreventionNot Availableunknown_status
NCT05200975
Target Attainment of CefuroximNo drug interventionstreatmentNot Availableunknown_status
NCT05846399
CAT BITE Antibiotic Prophylaxis for the Hand/Forearm (CATBITE)prevention4recruiting
NCT05090319
Micro-hematology Analyzer for Viral/Bacterial DescriptionNo drug interventionsNot AvailableNot Availableunknown_status
NCT06548841
Development and Validation of (Bio)Sensors for the Identification of PathogensNo drug interventionsNot AvailableNot Availablerecruiting
NCT03752424
Topical Silver Nanoparticles for Microbial Activitytreatment1unknown_status
NCT03440216
Population Pharmacokinetics and Pharmacodynamics of Beta-lactams of Interest in Adult Patients From Intensive Care UnitsotherNot Availableunknown_status
NCT06178822
Towards Novel BIOmarkers to Diagnose SEPsis on the Emergency RoomNo drug interventionsNot AvailableNot Availablerecruiting
NCT04011657
Effective Antimicrobial StewaRdship StrategIES (ARIES)No drug interventionshealth_services_researchNot Availablecompleted
NCT06143657
Clinical Performance Evaluation of AI-Enabled Automated Gram Staining DeviceNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT02754765
Evaluating Newly Approved Drugs for Multidrug-resistant TBtreatment3completed
NCT04067531
Treatment of BV With First Deqularum and Then Direkt After Clindamycintreatment3unknown_status
NCT04470973
Pharmacokinetics of Amikacin and Cefuroxime in Critically Ill Patients.Not AvailableNot Availableunknown_status
NCT04436991
Antibiotic Dosing in Geriatric Patients at the Emergency DepartmentNo drug interventionsNot AvailableNot Availablerecruiting
NCT04450680
Beta-lactam Therapeutic Drug Monitoring in SingaporeNo drug interventionsNot AvailableNot Availableunknown_status
NCT03148444
Impact of Antibiotic Treatment Following Implantation of Cardiac Electronic Device on Patient's Outcomeprevention4unknown_status
NCT04075344
Effect of a Infection Control Program on the Reduction of Bacterial Contamination on NG Tube Feeding in RCHEsNo drug interventionsotherNot Availableunknown_status
NCT04484740
Penetration of the Innovative Antibiotic Gepotidacin Into Prostate and Tonsillar Tissuetreatment1completed
NCT04070469
Plasma Concentrations of Amoxicillin Administered in High-doses During the First Week of Treatment (MAX-AMOX)treatment4unknown_status
NCT06093269
Pharmacokinetics Study of Cefazolin in Hemodialysis (CEFAZODIAL)treatment4recruiting
NCT03555981
Early Kangaroo Mother Care in Gambian Hospitalised Unstable NeonatesNo drug interventionstreatmentNot Availableterminated
NCT06166381
Parenteral Versus Combined Parenteral With Vancomycin-soaked Graft in ACL ReconstructionpreventionNot Availablenot_yet_recruiting
NCT06566495
Microorganisms on Reusable TourniquetsNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT05306314
Retrospective Chart Review of Treataprost Added to Antibiotic Treatment in Patients With Chronic ProstatitisNo drug interventionsNot AvailableNot Availableunknown_status
NCT02908399
Thermal Images on Smartphones to Diagnose Bacterial Pneumonia in Children in PakistanNo drug interventionsdiagnosticNot Availableunknown_status
NCT02381431
Use of Mobile Phones for Thermal Imaging of the Chest to Save Lives of Children With Pneumonia in Nagpur, IndiaNo drug interventionsdiagnosticNot Availablecompleted