Uremic Pruritus (DBCOND0037608)

Identifiers

Synonyms
Uremic pruritis / Uremic pruritus / Uremic pruritus (disorder) / Uraemic pruritus

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Ondansetron
A serotonin 5-HT3 receptor antagonist used to prevent nausea and vomiting in cancer chemotherapy and postoperatively.
Thalidomide
A medication used to treat cancers, particularly newly diagnosed multiple myeloma, and erythema nodosum leprosum.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT01660243
Efficacy and Safety of MT-9938 for Treatment of Uremic Pruritus in Subjects With End-stage Renal Disease Receiving Hemodialysistreatment2terminated
NCT04711603
A Phase III Clinical Study of MR13A9 in Hemodialysis Patients With Pruritus.treatment3completed
NCT03758079
Comparison of Gabapentin With Doxepin in the Management of Uremic Pruritustreatment4completed
NCT03002233
TRK-820 Study in Subjects on Hemodialysis With or Without Uremic PruritusNo drug interventionstreatment1completed
NCT03422653
A Study to Evaluate the Safety and Efficacy of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritus (KALM-1)treatment3completed
NCT05466045
Using of Extra Virgin Olive Oil in Hemodialysis Patients to Improve Pruritus and Sleep DisordersNo drug interventionssupportive_careNot Availableunknown_status
NCT01447693
Treatment of Uremic Pruritus by Olive-omega 3 OintmentNo drug interventionstreatment1 / 2unknown_status
NCT02373215
Phase 1 Study of Nalbuphine HCl ER Tablets in Hemodialysis Patients With Uremic Pruritustreatment1completed
NCT05885737
Phase 3 Study of Difelikefalin in Haemodialysis Chinese Adult Subjects With Moderate-to-Severe Pruritustreatment3active_not_recruiting
NCT03802617
A Clinical Study of MR13A9 in Hemodialysis Patients With Pruritus.treatment2completed
NCT02858726
Study to Evaluate IV CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritustreatment2 / 3completed
NCT06579066
The Effect of Probiotics vs Activated Charcoal in the Management of CKD Patients Suffering From Uremic Pruritus.treatment2not_yet_recruiting
NCT02143973
Open Label Extension Study of Nalbuphine HCl ER in Hemodialysis Patients With Uremic Pruritustreatment2 / 3completed
NCT01073501
Efficacy of Pregabalin in the Management of Chronic Uremic Pruritustreatment4unknown_status
NCT06446310
Phase 3 Study of QLG2198 in Haemodialysis Chinese Adult Subjects With Moderate-to-Severe PruritusNo drug interventionstreatment3recruiting
NCT06466421
Fexofenadine Versus Gabapentin for Uremic Pruritus in Patients on Regular Hemodialysistreatment4active_not_recruiting
NCT04728984
A Multi-site Bridging Study of Nalfurafine Hydrochloride Orally Disintegrating TabletNo drug interventionstreatment3unknown_status
NCT04470154
A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of HSK21542 Injection in Subjects Undergoing HemodialysisNo drug interventionstreatment2completed
NCT05575193
Acupressure on Uremic Pruritus and Sleep Quality Among Patients Receiving HemodialysisNo drug interventionstreatmentNot Availablecompleted
NCT00793156
A Randomized-Withdrawal Phase 3 Study Evaluating the Safety and Efficacy of Oral Nalfurafine HCl (AC-820)in Subjects on Hemodialysis With Uremic Pruritus (Renal Itch)No drug interventionstreatment3unknown_status
NCT00494975
The Effect of Phototherapy on Pruritus of Patients With Chronic Kidney DiseaseNo drug interventionstreatmentNot Availablecompleted
NCT04393675
Study to Investigate the Safety of LT5001 Drug Product for Uremic Pruritus in Hemodialysis PatientsNo drug interventionstreatment1 / 2unknown_status
NCT02696499
Treatment of Uremic Pruritus With PA101BNo drug interventionstreatment2completed
NCT01852318
Pregabalin for the Treatment of Uremic Pruritustreatment4unknown_status
NCT05525234
A Study of Thalidomide in the Treatment of Refractory Uremic Pruritustreatment4unknown_status
NCT03576235
Safety and Efficacy of PG102P for Uremic Pruritus in HD PatientsNo drug interventionstreatmentNot Availablecompleted
NCT03998163
CR845-CLIN3105: A Study to Evaluate the Safety and Effectiveness of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritustreatment3completed
NCT06159686
The Efficacy of Hemp-containing Cream Versus Placebo in the Treatment of Uremic PruritusNo drug interventionstreatment1 / 2completed
NCT02143648
Study of Nalbuphine HCl ER Tablets in Hemodialysis Patients With Uremic Pruritustreatment2 / 3completed
NCT04639674
AST-120 in Hemodialysis Patients With Uremic Pruritustreatment4completed
NCT02229929
Safety and Pharmacokinetics of IV CR845 in Hemodialysis Patients, and Its Efficacy in Patients With Uremic Pruritustreatment2completed
NCT03636269
CR845-CLIN3103: A Global Study to Evaluate the Safety and Efficacy of CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritustreatment3completed
NCT05031546
Intermediate-Size Patient Population Expanded Access Program for Intravenous DifelikefalinNot AvailableNot Availableapproved_for_marketing
NCT04650750
The Treatment Effect of Chinese Medicine Formula on Uremic Pruritustreatment0unknown_status
NCT03281538
Extension Study to Evaluate IV CR845 in Hemodialysis Patients With Moderate-to-Severe Pruritustreatment3completed
NCT05341843
Sertraline Effect in Uremic Pruritistreatment2completed