Pemphigus Vulgaris (PV) (DBCOND0040643)

Identifiers

Synonyms
Pemphigus Vulgaris / Pemphigus vulgaris (disorder) / Pemphigus, unspecified / Pemphigus / Pemphigus (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Dapsone
A sulfone drug used to treat acne vulgaris, Hansen's disease, and dermatitis herpetiformis.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT06663943
A Randomized Study on Pemphigus Treatment With Humanized CD38 Antibody CM313.treatment1 / 2not_yet_recruiting
NCT06654817
Efficacy and Safety Evaluation of Anti-CD20 Monoclonal Antibody Combined with Azathioprine and Corticosteroids in the Treatment of Pemphigus VulgarisNot AvailableNot Availablecompleted
NCT00683930
A Study to Assess the Effect of CellCept (Mycophenolate Mofetil) and Reduced Corticosteroids in Patients With Active Pemphigus Vulgaris (PV)treatment3completed
NCT04422912
A Phase 1/2, Open-label, Safety and Dosing Study of Autologous CART Cells (Desmoglein 3 Chimeric Autoantibody Receptor T Cells [DSG3-CAART] or CD19-specific Chimeric Antigen Receptor T Cells [CABA-201]) in Subjects With Active, Pemphigus Vulgaris (RESET-PV)No drug interventionstreatment1recruiting
NCT04598451
A Study to Assess the Efficacy and Safety of a Subcutaneous Formulation of Efgartigimod PH20 SC in Adults With Pemphigus (Vulgaris or Foliaceus)treatment3completed
NCT04598477
A Study to Assess the Long-term Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod PH20 SC in Adults With Pemphigus (Vulgaris or Foliaceus)treatment3terminated
NCT02753777
Autoimmune Blistering Diseases StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT00063752
Safety Study of PI-0824 to Treat Pemphigus Vulgaristreatment1completed
NCT01930175
Study of Efficacy and Safety of VAY736 in Patients With Pemphigus Vulgaristreatment2terminated
NCT03239470
Polyclonal Regulatory T Cells (PolyTregs) for PemphigusNo drug interventionstreatment1terminated
NCT04023149
Efficacy of Interleukin-2 Gargle in the Treatment of Oral Mucosa Lesion in Pemphigus Vulgaristreatment2unknown_status
NCT00606749
Use of KC706 for the Treatment of Pemphigus Vulgaristreatment2completed
NCT03780166
A Study of the Safety and Tolerability of INCB050465 in Pemphigus Vulgaristreatment2withdrawn
NCT05635266
Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research InitiativesNo drug interventionsNot AvailableNot Availablerecruiting
NCT05594472
Ozonated Olive Oil in Treatment of Pemphigus Vulgaris and Bullous Pemphigoidtreatment3recruiting
NCT04540133
Dexamethasone Solution and Dexamethasone in Mucolox™treatment2completed
NCT00429533
Efficacy of Dapsone as a Steroid Sparing Agent in Pemphigus Vulgaristreatment2terminated
NCT01920477
Efficacy and Safety of Ofatumumab in Treatment of Pemphigus Vulgaristreatment3terminated
NCT00626678
Azathioprine Versus Placebo in Pemphigus Vulgaris Treated With Prednisolonetreatment2completed
NCT03177213
Serum IL-21 Levels in Patients With Pemphigus VulgarisNo drug interventionsNot AvailableNot Availableunknown_status
NCT00483119
Randomized Trial of IVIg With or Without Cyclophosphamide in Pemphigustreatment2terminated
NCT05000216
COVID-19 Booster Vaccine in Autoimmune Disease Non-Respondersprevention2completed
NCT03334058
A Study to Evaluate the Safety, PD, PK and Efficacy of ARGX-113 in Patients With Pemphigustreatment2completed
NCT04096222
Comparative Analysis of the Th17 Cellular Response in Active and Inactive Pemphigus Vulgaris PatientsNo drug interventionsNot AvailableNot Availableunknown_status
NCT00135720
Study of Etanercept (Enbrel) in the Treatment of Pemphigus Vulgaristreatment2completed
NCT06581562
Open-label Single-Center Study to Evaluate the Safety and Efficacy of Combining Rituximab and AB-101 in B-cell Associated Autoimmune Diseases.treatment1recruiting
NCT04117529
Phenotypic and Functional Characterisation of Human B-cell Response in PemphigusNo drug interventionsbasic_scienceNot Availableunknown_status
NCT02704429
A Study of PRN1008 in Adult Patients With Pemphigus Vulgaristreatment2completed
NCT02383589
A Study to Evaluate the Efficacy and Safety of Rituximab Versus Mycophenolate Mofetil (MMF) in Participants With Pemphigus Vulgaris (PV)treatment3completed
NCT03075904
A Safety and Dose-Finding Study of SYNT001 in Subjects With Pemphigus (Vulgaris or Foliaceus)treatment1 / 2terminated
NCT05303272
A Study to Evaluate Efficacy and Safety of Abatacept in Participants of Pemphigus Vulgaris (PV)treatment4unknown_status
NCT05338112
Role of Tzanck Smear in Determining Pemphigus Vulgaris Disease ActivityNo drug interventionsNot AvailableNot Availableunknown_status
NCT06167408
Identifying Factors Influencing In-Hospital Relapse in Pemphigus PatientsNo drug interventionsNot AvailableNot Availablecompleted