Advanced Prostate Cancer (DBCOND0043429)

Identifiers

Synonyms
Advanced prostate cancer / Prostatic neoplasms malignant / Ca prostate / Malignant tumor of prostate (disorder) / Prostatic cancer / Prostate cancer NOS / Cancer of prostate / Prostate cancer / Malignant neoplasm of prostate / Primary malignant neoplasm of prostate (disorder)

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Degarelix
A GnRH receptor antagonist used in the management of advanced prostate cancer.
Histrelin
A GnRH agonist found in subcutaneous implants used for the treatment of pediatric patients with central precocious puberty and the palliative treatment of advanced prostate cancer.
Leuprolide
A peptide-based GnRH receptor superagonist used for the palliative treatment of prostate cancer, uterine leiomyomata, endometriosis, and central precocious puberty.
Relugolix
An oral GnRH receptor antagonist for androgen deprivation therapy in the treatment of advanced prostate cancer.
Triptorelin
A GnRH agonist indicated for the palliative treatment of advanced prostate cancer.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT06095089
A Study of JNJ-87189401 Plus JNJ-78278343 for Advanced Prostate CancerNo drug interventionstreatment1recruiting
NCT05800665
A Study Evaluating the Safety, Pharmacokinetics, and Activity of RO7656594 In Participants With Advanced or Metastatic Prostate CancerNo drug interventionstreatment1recruiting
NCT06463457
Comeback From Long coursE Androgen Deprivation Therapy (ADT) With RElugolix and Darolutamide (CLEARED)treatment2not_yet_recruiting
NCT01306890
A Registry of Sipuleucel-T Therapy in Men With Advanced Prostate CancerNot AvailableNot Availablecompleted
NCT02925702
PRORADIUM: Prospective Multi-centre Study of Prognostic Factors in mCRPC Patients Treated With Radium-223.Not AvailableNot Availableunknown_status
NCT02420977
Evaluation of PSMA-based PET as an Imaging Biomarker in Prostate CancerNo drug interventionsdiagnostic0active_not_recruiting
NCT01078545
Lucrin® Depot Efficacy and Safety Monitoring Study in Patients With Advanced Prostate Cancer and Lower Urinary Tract Symptoms (LUTS)Not AvailableNot Availablecompleted
NCT06490328
Efficacy and Safety of DKF-MA102 in Patients With Prostate Cancertreatment3recruiting
NCT03577028
Study of HPN424 in Patients With Advanced Prostate Cancertreatment1 / 2terminated
NCT03651271
Nivolumab With or Without Ipilimumab in Advanced Metastatic Cancertreatment2completed
NCT06555588
Engage Psychosocial Intervention for Cancer SymptomsNo drug interventionssupportive_careNot Availablenot_yet_recruiting
NCT02787837
PROSABI: Prospective Multi-centre Study of Prognostic Factors in mCRPC Patients Treated With Abiraterone Acetate.No drug interventionsNot AvailableNot Availableunknown_status
NCT03701659
TUPKRP Combined With MAB Therapy for LUTS/PCaNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT03938649
SRAM study_Postate CancerNo drug interventionstreatment2recruiting
NCT02922218
PROSENZA: Prospective Multi-Centre Study of Prognostic Factors in mCRPC Patients Treated With Enzalutamide.No drug interventionsNot AvailableNot Availableunknown_status
NCT03936218
Goserelin 10.8mg Injection in Treatment of Advanced Prostate Cancertreatment3recruiting
NCT01383863
A Long-term Observational Study Cohort in Patients With Advanced Prostate CancerNo drug interventionsNot AvailableNot Availablecompleted
NCT02234089
Therapy Pathways in the Treatment of Hormone Naïve Prostate Cancer Patients With and Without Comorbidities Treated With Degarelix or Luteinizing-Hormone-Releasing-Hormone (LHRH) Agonists.Not AvailableNot Availablecompleted
NCT05942001
Study of HRS-5041 in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC)No drug interventionstreatment1recruiting
NCT06006104
Phase 1/2 Clinical Study of HRS-4357 in Patients With Advanced Prostate CancerNo drug interventionstreatment1 / 2not_yet_recruiting
NCT03971110
A Study of Neoadjuvant Hormone Therapy in Patient With Advanced Prostate Cancer Undergoing Radical Prostatectomy.treatment4terminated
NCT06335914
Dual PSMA and FDG PET Imaging for Patients With Advanced Prostate CancerNo drug interventionsdiagnosticNot Availablenot_yet_recruiting
NCT06062745
Pilot Study for Detection of PSMA-Low CRPC-NE Tumors With Fluciclovine PET/CTdiagnostic1recruiting
NCT01224405
Prostate Cancer, Androgen Deprivation Withdrawal and Intermittent Chemotherapytreatment3unknown_status
NCT05590793
Effects of Triptorelin Pamoate 6-month When Given to Adult Chinese Participants With Advanced Cancer in the Prostatetreatment3completed
NCT00871585
Evaluation of Prostate-Specific Antigen (PSA) Levels in Patients With Advanced Prostate Cancer Treated With BicalutamideNo drug interventionsNot AvailableNot Availablecompleted
NCT02035124
Cabazitaxel and BKM120 in Patients With Metastatic Castrate-Resistant Prostate Cancer (mCRPC) Previously Treated With Docetaxeltreatment2withdrawn
NCT03511196
Intermittent Androgen Deprivation Therapy for Stage IV Castration Sensitive Prostate Cancertreatment0active_not_recruiting
NCT02362620
PROSTAC: Prospective Multi-centre Study of Prognostic Factors in mCRPC Patients Treated With Docetaxel or Cabazitaxel.No drug interventionsNot AvailableNot Availableunknown_status
NCT04117594
Whole Body Magnetic Resonance Imaging StudyNo drug interventionsNot AvailableNot Availableunknown_status
NCT06369246
PRORAD-5 PROstate RADiation in 5 Fractions: Phase Ib Five Fraction Radiotherapy for Patients With Advanced Prostate CancerNo drug interventionstreatment2recruiting