Severe Respiratory Syncytial Virus Infection (DBCOND0046343)

Identifiers

Synonyms

Not Available

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Palivizumab	A monoclonal anti respiratory syncytial virus F protein antibody used to prevent serious sequelae caused by respiratory syncytial virus infection in pediatric patients.	Fusion glycoprotein F0target Low affinity immunoglobulin gamma Fc region receptor III-Btarget Complement C1r subcomponenttarget Complement C1q subcomponent subunit Atarget Complement C1q subcomponent subunit Btarget Complement C1q subcomponent subunit Ctarget Low affinity immunoglobulin gamma Fc region receptor III-Atarget High affinity immunoglobulin gamma Fc receptor Itarget Low affinity immunoglobulin gamma Fc region receptor II-btarget
Ribavirin	A guanosine nucleoside used to treat some forms of Hepatitis C.	RNA-directed RNA polymerase Ltarget RNA-directed RNA polymerase catalytic subunittarget Inosine-5'-monophosphate dehydrogenase 1target Genome polyproteintarget Inosine-5'-monophosphate dehydrogenase 2target Adenosine kinaseenzyme Equilibrative nucleoside transporter 1transporter Solute carrier family 28 member 3transporter Cytosolic purine 5'-nucleotidaseenzyme

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT01075178	Retrospective Palivizumab Study in Children With Hemodynamically Significant Congenital Heart Disease	No drug interventions	Not Available	Not Available	completed