Metastatic Biliary Tract Cancer (DBCOND0046438)

Identifiers

Synonyms

Biliary cancer metastatic / Metastatic Biliary Cancer / Metastatic Biliary Cancers

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Durvalumab	An antineoplastic monoclonal antibody used to treat urothelial carcinoma and locally advanced, unresectable non-small cell lung cancer.	Programmed cell death 1 ligand 1target Programmed cell death protein 1target
Pembrolizumab	A PD-1 blocking antibody used to treat various types of cancer, including metastatic melanoma, non small-cell lung cancer, cervical cancer, head and neck cancer, and Hodgkin's lymphoma.	Programmed cell death protein 1target Programmed cell death 1 ligand 1target

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT03222258	Prospective Cohort Study Depending on the Use of Palliative Care for Advanced Stage of Cancer Patients	No drug interventions	Not Available	Not Available	completed
NCT03464968	mFOLFOX vs. mFOLFIRI in Advanced or Recurrent Biliary Tract Cancer Refractory to First Line	Irinotecan Leucovorin Oxaliplatin	treatment	2	completed
NCT05074472	A Phase 1/2, First-in-Human, Open Label, Dose Escalation Study Of A CSP Targeting Functional Antibody in Solid Tumors	ZB131	treatment	1 / 2	completed
NCT06548412	CTX-009 With Gemcitabine, Cisplatin, and Durvalumab as First-line Therapy in Patients With Unresectable or Metastatic Biliary Tract Cancers	Cisplatin Durvalumab Gemcitabine	treatment	1 / 2	not_yet_recruiting
NCT01096745	Randomized Trial of Gemcitabine/Cisplatin Versus S-1/Cisplatin in Advanced Biliary Cancer	Cisplatin Gemcitabine	treatment	2	terminated
NCT02866383	Immune Checkpoint Inhibition in Combination With Radiation Therapy in Pancreatic Cancer or Biliary Tract Cancer Patients	Ipilimumab Nivolumab	treatment	2	completed
NCT06282120	Efficacy and Safety of Irinotecan Liposome Injection Combined With 5-FU/LV± Immunotherapy in First-line Gemsitabine + Immunoprogressive Patients With Metastatic Biliary Tract Cancer	Fluorouracil Irinotecan Leucovorin	Not Available	Not Available	recruiting
NCT03524508	Nal-IRI(Nanoliposomal Irinotecan) Plus 5-FU/LV in Metastatic Biliary Tract Cancer	Fluorouracil Irinotecan Leucovorin	treatment	2	completed
NCT05742750	A Phase Ib/II Clinical Study of Camrelizumab and Apatinib Plus GP in the Treatment of Advanced Biliary Tract Cancer	Camrelizumab Cisplatin Gemcitabine Rivoceranib	treatment	1 / 2	not_yet_recruiting
NCT01375972	Trial of S-1 Plus Cisplatin (SP) Versus Gemcitabine Plus Cisplatin (GP) in Advanced Biliary Tract Adenocarcinoma	Cisplatin Gemcitabine	treatment	2	completed
NCT01843725	Phase 1 Study Testing the Combination of Aflibercept and Capecitabine in Metastatic Digestive and Breast Cancers	Aflibercept Capecitabine	treatment	1	completed