Hypoxic Respiratory Failure (DBCOND0046591)
Identifiers
- Synonyms
- Hypoxic respiratory failure / Respiratory failure / Failure respiratory / Respiration failure / Respiratory failure, unspecified
Associated Data
- Indicated Drugs and Targets
Drug Description Targets Nitric Oxide A vasodilating agent used in the treatment of hypoxic respiratory failure in premature neonates.- Guanylate cyclase soluble subunit alpha-2target
- Aldehyde dehydrogenase, mitochondrialenzyme
- Cytochrome P450 1A2enzyme
- Cytochrome P450 2B6enzyme
- Cytochrome P450 3A4enzyme
- Metallothionein-1Atarget
- Indoleamine 2,3-dioxygenase 1target
- Nitric oxide synthase 3target
- Guanylate cyclase soluble subunit alpha-1target
- Guanylate cyclase soluble subunit beta-1target
- Clinical Trials
Identifier Title Drug(s) Purpose Phase Status NCT03082105 Snow Physical Properties and Human Ventilatory Response No drug interventions basic_science Not Available completed NCT01069861 Study To Investigate Safety And Efficacy Of Sildenafil In The Newborns With Persistent Pulmonary Hypertension (PPHN) No drug interventions treatment 2 terminated NCT06501118 Optimizing Care in Critically Ill at UCHealth by Liberalizing the Target O2 in Mechanically-ventilated ICU Patients No drug interventions other Not Available not_yet_recruiting NCT05689216 Timed Awake Prone and Repositioning for Patients With Covid-19-induced Hypoxic Respiratory Failure. No drug interventions treatment Not Available not_yet_recruiting NCT06043635 Predictors of Inhaled Nitric Oxide Responsiveness in Patients With PPHN No drug interventions Not Available Not Available withdrawn NCT04380727 Almitrine and COVID-19 Related Hypoxemia No drug interventions Not Available Not Available completed NCT04433546 Pemziviptadil (PB1046), a Long-acting, Sustained Release Human VIP Analogue, Intended to Provide Clinical Improvement to Hospitalized COVID-19 Patients at High Risk for Rapid Clinical Deterioration and Acute Respiratory Distress Syndrome (ARDS). treatment 2 terminated NCT04385823 Use of High Flow Nasal Cannula Oxygen and Covid-19 Acute Hypoxemic Respiratory Failure No drug interventions Not Available Not Available completed NCT02184208 Retrospective Review of Mechanically Ventilated Patients Using a Continuous Data Collection System. No drug interventions Not Available Not Available completed NCT04344561 Incline Positioning in COVID-19 Patients for Improvement in Oxygen Saturation No drug interventions treatment Not Available terminated NCT06140056 Two Modes of Mechanical Ventilation for Intensive Care Patients With Low Blood Oxygen Due to Breathing Difficulties No drug interventions basic_science Not Available recruiting NCT03835741 Automated Adjustment of Oxygen on Patient With Acute COPD Exacerbation - FreeO2 HypHop No drug interventions treatment Not Available recruiting NCT04648657 Lung Ultrasound, PEEP and Overdistension (LUPO) No drug interventions Not Available Not Available completed NCT06336265 Diaphragmatic Ultrasound to Predict the Therapeutic Effect of High-flow Nasal Cannula Oxygen Therapy No drug interventions Not Available Not Available not_yet_recruiting NCT04415060 SedAting With Volatile Anesthetics Critically Ill COVID-19 Patients in ICU: Effects On Ventilatory Parameters And Survival treatment 3 recruiting NCT04049240 Effect of HFNO on Spontaneous Ventilation in Obese Patients During Analgo-sedation for Vitrectomy No drug interventions treatment Not Available unknown_status