Metastatic Gastric Cancers (DBCOND0063580)

Identifiers

Synonyms
Gastric Cancer, Metastatic / Metastatic Gastric Cancer / Gastric cancer stage IV NOS / Gastric cancer stage IV / Malignant neoplasm of stomach stage IV NOS / Gastric malignancy stage IV NOS / Stomach cancer stage IV NOS

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Capecitabine
A nucleoside metabolic inhibitor indicated to treat different gastrointestinal, including pancreatic cancer, and breast cancer.
Nivolumab
A PD-1 blocking antibody used to treat melanoma, non small-cell lung cancer, renal cell cancer, head and neck cancer, and Hodgkin lymphoma.
Trifluridine
A nucleoside metabolic inhibitor used to treat keratoconjunctivitis and epithelial keratitis caused by simplex virus, and as a part of chemotherapy for certain types of metastatic gastrointestinal cancers.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT06283121
A Clinical Study of BioTTT001 in Combination With SOX and Toripalimab in Patients With Gastric Cancertreatment2not_yet_recruiting
NCT06427252
The Efficacy and Safety of HIPEC Combined With PD-1 and SOX Chemotherapy for the Translational Treatment of GC or EGJC With PMNo drug interventionstreatment2not_yet_recruiting
NCT02976142
The Efficacy of Surgical Treatment After Neoadjuvant Chemotherapy Plus Intraperitoneal Immunotherapy Versus Chemotherapy Alone for Patients With Positive Wash Cytology Gastric CancerNo drug interventionstreatment2unknown_status
NCT01843725
Phase 1 Study Testing the Combination of Aflibercept and Capecitabine in Metastatic Digestive and Breast Cancerstreatment1completed
NCT06157892
A Study of Disitamab Vedotin Alone or With Other Anticancer Drugs in Solid Tumorstreatment1 / 2recruiting
NCT06251973
A Study of agenT-797 in Combination With Botensilimab, Balstilimab, Ramucirumab, and Paclitaxel for People With Esophageal, Gastric, or Gastro-esophageal Junction Cancertreatment2recruiting
NCT06264921
A Study With NKT3447 for Adults With Advanced/Metastatic Solid TumorsNo drug interventionstreatment1recruiting
NCT06586957
A Study with NKT3964 for Adults with Advanced/Metastatic Solid TumorsNo drug interventionstreatment1not_yet_recruiting
NCT04510064
PD-1 Antibody Combined With Modified FLOT Regimen in the Treatment of Unresectable Locally Advanced or Limited Metastatic Gastric Cancertreatment2unknown_status
NCT04166721
WaKING: Wnt and checKpoint INhibition in Gastric Cancertreatment1 / 2active_not_recruiting
NCT04739202
Personalized Targeted IMMUNOtherapy-based Regimens in Recurrent GASTric Adenocarcinoma (IMMUNOGAST)treatment2unknown_status
NCT03751761
GC 2nd Line Durvalumab(MEDI4736)/Tremelimumab Plus Paclitaxel Studytreatment1 / 2completed
NCT03121807
Home Parenteral Nutrition for Malnourished Unresectable Stage IV Gastric Cancersupportive_careNot Availablecompleted
NCT05143970
A Phase 1 First-In-Human Study of the Anti-CD73 IPH5301 Alone or in Combination With Chemotherapy and Trastuzumab in Patients With Advanced Solid Tumorstreatment1recruiting
NCT02204306
Genotype Guided Chemotherapy in Gastric Cancer PatientsNo drug interventionstreatment2completed
NCT06250036
Peri-operative Zimberelimab (Anti-PD-1) vs Zimberelimab in Combination With Domvanalimab (Anti-TIGIT) in Resectable Mismatch Repair Deficient/Micro-satellite Unstable Gastric and Gastro-oesophageal Junctional Adenocarcinoma (ZODIAC)treatment2not_yet_recruiting
NCT03614013
Resistance to Immunotherapy in Gastric CancerNo drug interventionsNot AvailableNot Availableunknown_status
NCT05714124
Liver Embolization Approaches for Tumor ManagementNo drug interventionsNot AvailableNot Availablerecruiting
NCT03698825
TEW-7197 With Paclitaxel for the Treatment of Metastatic Gastric Cancertreatment1 / 2unknown_status
NCT06008925
Clinical Study of VG161 Combined With Nivolumab Injection in Patients With Advanced Metastatic Gastric Cancertreatment1 / 2recruiting
NCT05765357
Clinical Study to Compare the Pharmacokinetics and Safety of Trastuzumab for Injection With Herceptin® in Healthy Male Volunteerstreatment1completed
NCT02065765
International Expanded Access Program to Provide Ramucirumab for the Treatment of Metastatic Gastric CancerNot AvailableNot Availableno_longer_available
NCT01099527
A Trial of RAD001/Capecitabine in Refractory Gastric Cancertreatment1 / 2completed
NCT02076594
Low-Tox Vs Eox In Patients With Locally Advanced Unresectable Or Metastatic Gastric Cancertreatment3terminated
NCT05940844
Study of OB-002 in Patients With Refractory Metastatic CancerNo drug interventionstreatment1not_yet_recruiting
NCT00632268
Low-dose RAD001(Everolimus) Plus Cisplatin-HDFL Chemotherapy for the First-line Treatment of Advanced Gastric Cancertreatment2completed
NCT05024812
Fruquintinib Combined With Toripalimab and SOX Regimen in the First-line Treatment of Advanced Metastatic Gastric or Gastroesophageal Junction Adenocarcinomatreatment1 / 2recruiting
NCT02310464
Trial of Active Immunotherapy With OBI-833 (Globo H-CRM197) in Advanced/Metastatic Gastric, Lung, Colorectal or Breast Cancer Subjectstreatment1completed
NCT05955833
89Zr-DFO*-Trastuzumab PET in Patients With Gastric or Breast Cancer - a Pilot StudyNo drug interventionsdiagnostic1recruiting
NCT04358354
Triplet Combination of Cytotoxics as First-line Treatment for Metastatic Gastric Cancertreatment3recruiting
NCT05859477
Nivolumab in Combination With Chemotherapy for FGFR2-positive Metastatic Gastric Cancertreatment2recruiting
NCT01359397
Docetaxel, Oxaliplatin, Capecitabine, Bevacizumab and Trastuzumab in Patients With Locally Advanced or Metastatic Gastric CancerNot Available2unknown_status
NCT03154983
The Clinical Research of Mesylate Apatinib Combined With Docetaxel and S-1 as the First-line Treatment of Metastatic Gastric Cancertreatment2unknown_status
NCT05230771
Clinical Outcome of Palliative Surgery After Translational Therapy for Metastatic Gastric Cancer Versus Maintenance Chemotherapy for Metastatic Gastric CancerNo drug interventionstreatment3not_yet_recruiting
NCT02855788
Metronomic Chemotherapy in Advanced Gastric Cancertreatment2unknown_status
NCT04618809
Improving the Approach to and Management of the Older Patient With Metastatic Gastric CancerNo drug interventionshealth_services_researchNot Availablerecruiting
NCT06121700
Radiotherapy + Chemoimmunotherapy Followed by Surgery in Patients With Limited Metastatic Gastric or GEJ Cancertreatment2recruiting
NCT04263870
Conversion Therapy With Sintilimab Plus CAPOX in Patients With Unresectable Locally Advanced or Limited Metastatic Adenocarcinoma of the Stomach or Esophagogastric Junctiontreatment2unknown_status
NCT00253370
Sorafenib, Docetaxel, and Cisplatin in Treating Patients With Metastatic or Advanced Gastric or Gastroesophageal Junction Cancertreatment2completed
NCT03409848
Ipilimumab or FOLFOX in Combination With Nivolumab and Trastuzumab in HER2 Positive EsophagoGastric Adenocarcinomatreatment2completed
NCT05025826
Study Evaluating Neurotoxicity in Patients With Metastatic Gastro Intestinal Cancer Taking Phycocare® or Placebo During Oxaliplatin Based ChemotherapyNo drug interventionspreventionNot Availablerecruiting
NCT02668380
An Open Label, Prospective, Multicentre, Non-interventional Study of Apatinib for Chemotherapy-Refractory Advanced Metastatic Gastric CancerNo drug interventionsNot AvailableNot Availableunknown_status
NCT01528501
Histone Deacetylases - Gastric Cancer (HDAC-GaCa-2008)treatment2terminated
NCT02002195
Modified Folinic Acid-Fluorouracil-Oxaliplatin Regimen + Capecitabine for Elderly With Metastatic Gastric CancerNot AvailableNot Availableunknown_status
NCT05703555
INTRUSION: Unraveling the INTRatUmoral PK/PD relatION for SAR408701treatment2withdrawn
NCT01814150
The Association Between Alpha 1 Acid Glycoprotein Level and Outcome Metastatic Cancer Treated With DocetaxelNo drug interventionsNot AvailableNot Availableunknown_status