Depressive Episodes (DBCOND0065091)

Identifiers

Synonyms
Acute depressive episodes / Depressive Episode / Acute Depressive Episode / Major depressive disorder, single episode, unspecified / Major depressive disorder, single episode / Major depression, single episode (disorder) / Episode of depression (finding) / Feeling down / Mood depression / Mood depressions / Depressed mood / Depressive disorder (disorder) / Low mood / Feeling blue / Dysthymic disorder / Depression, unspecified / Depressive illness / Dysthymia (disorder) / Depressive neurosis / Depressive disorder / Depressive disorders / Major depressive disorder, recurrent, unspecified / Depressive state / Depression NOS / Depressed state / Depression / Depression mental

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Cariprazine
An atypical antipsychotic used to treat schizophrenia and acute manic or mixed episodes due to bipolar I disorder.
Lumateperone
A novel 2nd generation antipsychotic used to manage both positive and negative symptoms in patients with schizophrenia.
Olanzapine
An antipsychotic drug used in the management of schizophrenia, bipolar 1 disorder, and agitation associated with these disorders.
Quetiapine
An atypical antipsychotic agent used for the management of bipolar disorder, schizophrenia, and major depressive disorder.
Tranylcypromine
A monoamine oxidase inhibitor used to treat major depressive disorder.
Valproic acid
An anticonvulsant used to control complex partial seizures and both simple and complex absence seizures.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT01893749
Primary Care Internet Based Depression Prevention for Adolescents (CATCH-IT) Also Known as Promoting AdolescenT HealthNo drug interventionspreventionNot Availablecompleted
NCT05683028
RCT for Electroconvulsive Treatment Followed by Cognitive Control TrainingNo drug interventionstreatmentNot Availablecompleted
NCT06152705
Comparing the Efficacy of FMRI-Guided Vs. Standard ITBS in Treating DepressionNo drug interventionstreatmentNot Availablerecruiting
NCT04572321
Youth Depression and Suicide Research NetworkNo drug interventionsNot AvailableNot Availablerecruiting
NCT03449979
Single Session of tACS in a Depressive EpisodeNo drug interventionsbasic_scienceNot Availablecompleted
NCT05691647
Chronotherapy for Depressive EpisodesNo drug interventionstreatmentNot Availablerecruiting
NCT02481245
BezafibrateTreatment for Bipolar Depression: A Proof of Concept Studytreatment2unknown_status
NCT01879111
Increasing the Efficiency of Depression-screening Using Patient-targeted FeedbackNo drug interventionsscreeningNot Availablecompleted
NCT05547711
Prediction and Validation of Unipolar Depression With Psychosocial-somatic Markers in a Naturalistic Cohort Recruited in an Outpatient SettingNo drug interventionsotherNot Availablenot_yet_recruiting
NCT04171193
Efficacy of Deep Anaesthesia With Isoflurane as a Fast-response Antidepressant Agenttreatment2unknown_status
NCT04383509
Electroconvulsive Treatment Followed by Cognitive Control TrainingNo drug interventionstreatmentNot Availableterminated
NCT05910775
Role Of Non-Specific Effects in The Treatment of Depression With EsketamineNo drug interventionsotherNot Availableenrolling_by_invitation
NCT05461599
Digital Therapeutic for Adolescent Depressive Symptoms in Cardiology and GastroenterologyNo drug interventionstreatmentNot Availableterminated
NCT03944213
Resting-state Functional Connectivity Throughout a Course of iTBS in Major DepressionNo drug interventionsNot AvailableNot Availableunknown_status
NCT05260086
Pre-mapping Networks for Brain Stimulation 2No drug interventionstreatmentNot Availablecompleted
NCT04469322
Pharmacogenetic Implementation Trial in Veterans With Treatment Refractory DepressionNo drug interventionstreatmentNot Availablecompleted
NCT05708222
Sleep Signal Analysis for Current Major Depressive Episode (SAMDE)No drug interventionsNot AvailableNot Availablecompleted
NCT01212848
Transcranial Magnetic Stimulation (TMS) for Suicidal IdeationNo drug interventionstreatment3unknown_status
NCT04658420
A Single Ketamine Infusion Combined With Music for Suicidal Ideationtreatment2unknown_status
NCT06355180
Esketamine Treatment for Depressive Episodes With Suicidal Ideation in Mood Disorderstreatment4not_yet_recruiting
NCT04990401
Behavioral Activation Teletherapy to Increase Physical ActivityNo drug interventionstreatmentNot Availablerecruiting
NCT04123301
Theta-Burst Stimulation in Major Depressive Episodes With Mixed Characteristics.No drug interventionstreatmentNot Availableunknown_status
NCT03899168
Confirmation Bias Towards Treatments of Depressive Disorders in Social TaggingNo drug interventionshealth_services_researchNot Availablecompleted
NCT03288714
Adaptive Design Study of NEST sTMS in Subjects With Major Depressive DisorderNo drug interventionstreatmentNot Availablecompleted
NCT05641623
OSU6162 as add-on in SSRI/SNRI-resistant Depressiontreatment2recruiting
NCT04239521
The Epidemiology, Management, and the Associated Burden of Related Conditions in Alopecia AreataNo drug interventionsNot AvailableNot Availablecompleted
NCT03537547
Combinatorial Pharmacogenomics Testing in Treatment-Naïve Major Depressive DisorderNo drug interventionstreatment4terminated
NCT05701345
Study of Virtual Reality-based Medical Device for Patients With Depressive DisorderNo drug interventionstreatmentNot Availableenrolling_by_invitation
NCT03126188
Study of the Effect of Antidepressant Drugs on Neurotrophic Factors in Patients With DepressionNot AvailableNot Availablecompleted
NCT05678907
Predictive Value of the DD4 Questionnaire on Depressive Relapse After HospitalizationNo drug interventionsNot AvailableNot Availablerecruiting
NCT05462652
Self-guided Treatment for Adolescents Navigating DepressionNo drug interventionstreatmentNot Availablecompleted
NCT04081519
Stimulation of Parieto-hippocampal Connectivity in Patients With Major Depressive DisorderNo drug interventionstreatmentNot Availablecompleted
NCT05206734
Risk of Mental Health Conditions in Children and Young Adults With Inflammatory Bowel Disease and Influence on HealthNo drug interventionsNot AvailableNot Availablecompleted
NCT06426134
Ketosis Impact on Signs & Symptoms of Schizophrenia and Bipolar disorderSNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT05654948
Characterisation of Fundamental Decision Making in People Suffering From a Characterised Depressive EpisodeNo drug interventionsNot AvailableNot Availablerecruiting
NCT05351866
Digital Therapeutic for Adolescent Depressive Symptoms in Hematology, Oncology, and Weight ManagementNo drug interventionstreatmentNot Availableterminated
NCT03543410
A Clinical Study to Test the Effectiveness of an Investigational Drug to Treat People That Have Major Depressive Episodes When They Have Bipolar 1 DepressionNo drug interventionstreatment2completed
NCT01520350
Low-Dose Adjunctive Aripiprazole in the Treatment of Bipolar Depression: Double-Blind Placebo-Controlled Pilot Studytreatment3terminated
NCT05686408
Study to Evaluate TNX-601 ER Monotherapy Versus Placebo in Patients With Major Depressive Disorder (MDD)treatment2completed
NCT04953338
Mental Health Associations With VitiligoNo drug interventionsNot AvailableNot Availablecompleted
NCT01467700
Efficacy and Safety of Ramelteon Sublingual in Adult Patients With Acute Depressive Episodes Associated With Bipolar I Disordertreatment3terminated