Pancreatic Metastatic Cancer (DBCOND0070216)

Identifiers

Synonyms
Metastatic Pancreatic Cancer / Metastatic Pancreatic Cancers / Pancreatic Cancer Metastatic / Pancreatic Cancer, Metastatic / Pancreas Cancer, Metastatic / Metastatic Cancer Pancreas / Metastatic Pancreas Cancer / Metastases to pancreas / Malignant neoplasm of pancreas metastatic / Pancreas neoplasm malignant metastatic / Secondary malignant neoplasm of pancreas (disorder) / Pancreatic carcinoma stage IV / Pancreatic carcinoma metastatic

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Erlotinib
An EGFR tyrosine kinase inhibitor used to treat certain small cell lung cancers or advanced metastatic pancreatic cancers.
Leucovorin
A folate analog used to treat the toxic effects of methotrexate and other folate antagonists, to treat megaloblastic anemia, and to provide palliative treatment of colorectal cancer.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT01600807
OSI-906 With Gemcitabine and Erlotinib for Metastatic Ductal Adenocarcinoma of the Pancreastreatment1 / 2withdrawn
NCT02143219
Efficacy and Tolerance Evaluation in FOLFIRINOX Dose Adjusted in Elderly Patients With a Metastatic Pancreatic Cancertreatment2completed
NCT01174121
Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Cancertreatment2recruiting
NCT03816163
A Study of Zolbetuximab (IMAB362) in Adults With Pancreatic Cancertreatment2active_not_recruiting
NCT04229004
A Multi-center Trial to Evaluate Multiple Regimens in Metastatic Pancreatic Cancertreatment3active_not_recruiting
NCT06106568
An Observational Study to Learn More About the Impact of Gadoxetate Sodium-Enhanced Magnetic Resonance Imaging (EOB-MRI) When Used to Diagnose the Spread of Cancer From the Pancreas to the Liver in Japanese People Under Real-World ConditionsNo drug interventionsNot AvailableNot Availablecompleted
NCT06533332
A Phase 1 Trial of ERX-315 in Participants With Advanced Solid TumorsNo drug interventionstreatment1recruiting
NCT06662669
YL-13027 and/or HY-0102 Combined With AG Regimen Chemotherapy for Metastatic Pancreatic Cancertreatment1 / 2not_yet_recruiting
NCT04820179
Atezolizumab + Cabozantinib in Patients W/ Metastatic, Refractory Pancreatic Cancertreatment2recruiting
NCT05042128
The ASCEND Study: Gemcitabine and Nab-Paclitaxel With LSTA1 (Certepetide) or Placebo in Patients With Untreated Metastatic Pancreatic Ductal Adenocarcinomatreatment2active_not_recruiting
NCT06199466
A Trial of YL-13027 in Combination With Gemcitabine and Nab-paclitaxel in Patients With Refractory Metastatic Pancreatic Cancertreatment1active_not_recruiting
NCT06592664
LSTA1 Phase 1b/2a Continuous Infusion Trial in mPDACtreatment1 / 2not_yet_recruiting
NCT00630552
QUILT-2.019: A Study of AMG 655 or AMG 479 in Combination With Gemcitabine for Treatment of Metastatic Pancreatic Cancertreatment1 / 2completed
NCT05659914
Olaparib and Durvalumab (MEDI4736) in Patients with Metastatic Pancreatic Cancer and DNA Damage Repair Genes Alterationstreatment2active_not_recruiting
NCT06621095
Anlotinib Plus Benmelstobart and AG in First-line Treatment of Advanced Metastatic Pancreatic Cancer (ALTER-PA-001)treatment2not_yet_recruiting
NCT04222413
Metarrestin (ML-246) in Subjects With Metastatic Solid TumorsNo drug interventionstreatment1recruiting
NCT05360732
Redefining FOLFIORINOX in Older Pancreatic Cancer PatientsNo drug interventionstreatment2recruiting
NCT05442749
Niraparib As First Line Therapy with Metastatic Homologous Repair-deficient Pancreatic Cancertreatment2withdrawn
NCT06483555
Basal-like PDAC Treated With Gemcitabine, Erlotinib, and Nab-paclitaxeltreatment1 / 2not_yet_recruiting
NCT04409002
Niraparib + Dostarlimab + RT in Pancreatic Cancertreatment2completed
NCT04002479
Alpha Radiation Emitters Device for the Treatment of Advanced Pancreatic CancerNo drug interventionstreatmentNot Availablerecruiting
NCT01839487
PEGPH20 Plus Nab-Paclitaxel Plus Gemcitabine Compared With Nab-Paclitaxel Plus Gemcitabine in Participants With Stage IV Untreated Pancreatic Cancertreatment2completed
NCT06078787
Olaparib in PALB2 Advanced Pancreatic Cancertreatment2recruiting
NCT00652054
Phase 2 Study of S-1 as 2nd Line Therapy in Metastatic Pancreatic CancerNo drug interventionstreatment2completed
NCT01744353
BrUOG 278: FOLFOX-A For Pancreatic Cancer A Brown University Oncology Research Group Studytreatment1completed
NCT03261947
A Study to Evaluate the Safety, Tolerability, and Activity of TAK-931 in Participants With Metastatic Pancreatic Cancer, Metastatic Colorectal Cancer, and Other Advanced Solid Tumorstreatment2completed
NCT00761345
Study of Low-Dose Fractionated Radiotherapy in Patients With Locally Advanced Metastatic Pancreatic Cancertreatment1completed
NCT05360745
Quality of Life With Nutritional Supplementation in Patients With Locally Advanced/Metastatic Pancreatic Cancer.No drug interventionssupportive_careNot Availablewithdrawn
NCT02866383
Immune Checkpoint Inhibition in Combination With Radiation Therapy in Pancreatic Cancer or Biliary Tract Cancer Patientstreatment2completed
NCT00986661
A Study to Assess PV-10 Chemoablation of Cancer of the Livertreatment1active_not_recruiting
NCT01510561
A Study of Fractionated 90Y-hPAM4 Plus Gemcitabine in Pancreatic Cancer Patients Receiving at Least 2 Prior Therapies.treatment1withdrawn
NCT00326911
Cetuximab and Bevacizumab With or Without Gemcitabine to Treat Metastatic Pancreatic Cancertreatment2terminated
NCT01210911
Metformin Combined With Chemotherapy for Pancreatic Cancertreatment2completed
NCT02205788
Feasibility of Biodynamic Imaging for Predicting Therapeutic Effect in Metastatic Adenocarcinoma of the PancreasNo drug interventionsNot AvailableNot Availablewithdrawn
NCT06538207
An Open-label, Uncontrolled Study of ONO-4578 and ONO-4538 in Combination With Standard-of-care Modified FOLFIRINOX (mFFX) or Gemcitabine Plus Nab-paclitaxel (GnP) Therapy as First-line Treatment in Patients With Metastatic Pancreatic Cancertreatment1active_not_recruiting
NCT05929885
Metronomic Capecitabine, Oxaliplatin and UGT1A1 Genotype-directed Irinotecan in Metastatic Pancreatic Cancer PatientsNo drug interventionstreatment2recruiting
NCT03602885
EL CENTRO: Engaging Latinos in the Center of Cancer Treatment OptionsNo drug interventionshealth_services_researchNot Availablecompleted
NCT02352337
First-line Metastatic Pancreatic Cancer : FOLFIRINOX +/- LV5FU2 in Maintenance Versus Firgemtreatment2completed
NCT03666832
Multi-center, Open-label, Phase 1b Clinical Trial to Evaluate the Safety, Tolerability, and Exploratory Efficacy of TEW-7197 in Combination With FOLFOX in Patients With Metastatic Pancreatic Ductal Adenocarcinoma Who Have Failed First-Line Gemcitabine and Nab-Paclitaxeltreatment1 / 2unknown_status
NCT02691052
Observational Study on Quality of Life of Patients Receiving Nab-paclitaxel/Gemcitabine First Line Therapy, Including a Translational ProgramNo drug interventionsNot AvailableNot Availablecompleted
NCT01040000
QUILT-3.019: Phase 2 Study of NPC-1C Chimeric Monoclonal Antibody to Treat Pancreatic and Colorectal Cancertreatment1 / 2completed
NCT01417000
Safety and Efficacy of Combination Listeria/GVAX Immunotherapy in Pancreatic Cancertreatment2completed
NCT02983500
Patient Reported Outcomes Registry in Patient With Cancer CachexiaNo drug interventionsNot AvailableNot Availablecompleted
NCT02707159
Circulating Tumor Cells as Tools for Therapy Response in Nab-paclitaxel Treated Metastatic Pancreatic Cancer Patientsdiagnostic2completed
NCT05138159
A Study of Donafenib Plus S-1 in Treating Patients With Metastatic Pancreatic Cancer After Chemotherapy With Nab-paclitaxel Plus Gemcitabine Regimentreatment2unknown_status
NCT03821870
Predictive Value of Analysing Tissue From Patients With Metastatic Pancreatic Cancer for Drug SensitivityNo drug interventionsNot AvailableNot Availablecompleted
NCT04844970
Anamorelin Study for Advanced Pancreatic Cancersupportive_care2recruiting
NCT02967770
Molecularly Tailored Therapy to Standard of Care as Second-Line Therapy in Metastatic Pancreatic CancerNo drug interventionstreatment2withdrawn
NCT05143970
A Phase 1 First-In-Human Study of the Anti-CD73 IPH5301 Alone or in Combination With Chemotherapy and Trastuzumab in Patients With Advanced Solid Tumorstreatment1recruiting
NCT04150042
SHARON: A Clinical Trial for Metastatic Cancer With a BRCA or PALB2 Mutation Using Chemotherapy and Patients' Own Stem Cellstreatment1recruiting
NCT01130142
A Study Evaluating IPI-926 in Combination With Gemcitabine in Patients With Metastatic Pancreatic Cancertreatment1 / 2completed
NCT02028806
mFOLFIRINOX as First-Line Chemotherapy in Treating Chinese Patients With Metastatic Pancreatic Cancertreatment2completed
NCT01494506
Study of MM-398 With or Without 5-FU/LV, Versus 5-FU/LV in Patients With Metastatic Pancreatic Cancertreatment3completed
NCT00844649
Phase III Study of ABI-007(Albumin-bound Paclitaxel) Plus Gemcitabine Versus Gemcitabine in Metastatic Adenocarcinoma of the Pancreastreatment3completed
NCT02555813
Treatment of Pancreatic Cancer With AbraxaneNot AvailableNot Availablecompleted
NCT02109341
Phase I/II Study to Evaluate Nab-paclitaxel in Substitution of CPT11 or Oxaliplatin in FOLFIRINOX Schedule as First Line Treatment in Metastatic Pancreatic Cancertreatment1 / 2completed
NCT02340117
Study of Combined SGT-53 Plus Gemcitabine/Nab-Paclitaxel for Metastatic Pancreatic Cancertreatment2unknown_status
NCT01964534
Efficacy of ABI-007 Plus Gemcitabine or sLV5FU2 as First-line Therapy in Patients With Metastatic Pancreatic Cancertreatment2unknown_status
NCT01934634
Phase I Trial of LCL161 and Gemcitabine Plus Nab-Paclitaxel in Metastatic Pancreatic Cancertreatment1unknown_status
NCT01571024
BKM120 + mFOLFOX6 in Advanced Solid Tumors With Expansion Cohort Pancreatic Cancertreatment1completed
NCT05714124
Liver Embolization Approaches for Tumor ManagementNo drug interventionsNot AvailableNot Availablerecruiting
NCT05586516
A Study to Assess an ATX Inhibitor (IOA-289) in Patients With Metastatic Pancreatic Cancertreatment1 / 2recruiting
NCT03487016
First-line Therapy in Metastatic PDACtreatment2unknown_status
NCT00922896
Trial of Erlotinib, Gemcitabine and Cisplatin in Metastatic Pancreatic Cancertreatment2completed
NCT06018896
Vitamin C to Quality of Life in Patients With Terminal Stage Pancreatic Cancertreatment2recruiting
NCT02697058
Phase II of BAX2398/5-FU/Calcium Levofolinate in Pancreatic Cancertreatment2completed
NCT03468335
2nd-line Therapy With Nal-IRI After Gem/Nab-pac in Advanced Pancreatic Cancer - Predictive Role of 1st-line Therapytreatment3active_not_recruiting
NCT02404363
Safety and Efficacy of Clopidogrel in Locally Advanced and Metastatic Pancreatic Adenocarcinoma Treated With Chemotherapytreatment3terminated
NCT05417386
FOLFIRINOX + NIS793 in Pancreatic Cancertreatment1terminated
NCT00398086
Gemcitabine Plus Albumin-bound Paclitaxel In Patients With Advanced Metastatic Pancreatic Cancertreatment1 / 2completed
NCT03168139
Olaptesed (NOX-A12) Alone and in Combination With Pembrolizumab in Colorectal and Pancreatic Cancertreatment1 / 2completed
NCT00447122
BrUOG-PA-209: Lapatinib and Gemcitabine for Metastatic Pancreaticobiliary Cancertreatment1terminated
NCT02282722
Improving Informed Consent for Palliative ChemotherapyNo drug interventionsotherNot Availablecompleted
NCT00954525
Intravenous Vitamin C in Combination With Standard Chemotherapy for Pancreatic Cancertreatment1completed
NCT05634525
Phase Ib Trial of the KRASG12C Inhibitor Adagrasib (MRTX849) in KRAS G12C Mutant Metastatic Pancreatic Cancer Patientstreatment1recruiting
NCT02362048
ACP-196 Alone and in Combination With Pembrolizumab in Subjects With Advanced or Metastatic Pancreatic Cancertreatment2completed
NCT01523457
Study of Modified FOLFIRINOX in Advanced Pancreatic CancerNo drug interventionstreatment2completed
NCT00709826
APRiCOT-P: Study of Apricoxib With Gemcitabine and Erlotinib to Treat Advanced Pancreatic Cancertreatment2completed
NCT04212026
Irreversible Electroporation (IRE) Followed by Nivolumab in Patients With Metastatic Pancreatic Cancer.treatment2terminated
NCT05869474
Implantation of iodine125-Seeds Combined With Chemotherapy in the Treatment of Metastatic Pancreatic CarcinomaNo drug interventionstreatmentNot Availablerecruiting
NCT00919282
Gemcitabine (GFF) in Patients With Pancreatic Cancertreatment2completed
NCT01796782
QYHJ Granules Versus Xeloda in Metastatic Pancreatic Cancertreatment2unknown_status
NCT06532331
A PhaseⅠStudy of ONO-7475 in Combination With ONO-4538 and Gemcitabine Plus Nab-paclitaxel (GnP), the Standard of Care, and ONO-7475 in Combination With GnP in Patients With Pancreatic Cancertreatment1recruiting
NCT00837031
Lenalidomide With Gemcitabine in Treatment of Untreated Advanced Carcinoma of the Pancreastreatment2completed
NCT02734160
A Study of Galunisertib (LY2157299) and Durvalumab (MEDI4736) in Participants With Metastatic Pancreatic Cancertreatment1completed
NCT03929094
Nab-paclitaxel and Gemcitabine in Metastatic Pancreatic Cancertreatment2unknown_status
NCT04361162
Nivolumab + Ipilimumab + Radiation in MSS Pancreatic Cancertreatment2active_not_recruiting
NCT05642962
Pancrelipase in People With Pancreatic Ductal Adenocarcinoma (PDAC)treatment1 / 2recruiting
NCT00245362
A Phase II Trial of CG 8020 and CG 2505 in Patients With Nonresectable or Metastatic Pancreatic CancerNo drug interventionstreatment2completed
NCT03331562
A SU2C Catalyst® Trial of a PD1 Inhibitor With or Without a Vitamin D Analog for the Maintenance of Pancreatic Cancertreatment2completed
NCT01303029
Safety and Efficacy Study of Gemcitabine-erlotinib Versus Gemcitabine-erlotinib-capecitabine in Patients With Metastatic Pancreatic Cancertreatment2completed
NCT03435289
A Study of CPI-613 With Gemcitabine and Nab-paclitaxel for Patients With Advanced or Metastatic Pancreatic Cancertreatment1unknown_status
NCT04498689
Efficacy and Safety of Camrelizumab Combined With Nab-Paclitaxel Plus Gemcitabine for Metastatic Pancreatic Cancertreatment2unknown_status
NCT05940844
Study of OB-002 in Patients With Refractory Metastatic CancerNo drug interventionstreatment1not_yet_recruiting
NCT03563144
QUILT-3.088: NANT Pancreatic Cancer Vaccinetreatment2withdrawn
NCT00744640
Gemcitabine, Oxaliplatin and Capecitabine for Advanced Pancreatic Carcinomatreatment1 / 2completed
NCT04718701
Anlotinib, Toripalimab and Nab-paclitaxel in Locally Advanced/Metastatic Pancreatic Cancertreatment2unknown_status
NCT06059001
Study to Evaluate the Safety, PK, and Efficacy of the Myc Inhibitor OMO-103 Administered iv in Patients With PDACtreatment1recruiting
NCT03086369
A Study of Nab-Paclitaxel and Gemcitabine With or Without Olaratumab (LY3012207) in Participants With Metastatic Pancreatic Cancertreatment1 / 2completed
NCT01946646
Phase I Study of TS-1 With Concurrent Radiotherapy to Treat Pancreatic CancerNo drug interventionstreatment1terminated
NCT02921646
Relationship Between Evolution of Resting Energy Expenditure and Tumoral Response to Chemotherapy in Patients Suffering From Pancreas CancerNo drug interventionsotherNot Availableterminated
NCT06168812
A Study of Glipizide to Treat High Blood Sugar in People With Pancreatic Cancertreatment2recruiting
NCT01956812
Phase 3 Trial of 90Y-Clivatuzumab Tetraxetan & Gemcitabine vs Placebo & Gemcitabine in Metastatic Pancreatic Cancertreatment3terminated
NCT03785210
Nivolumab (Anti-PD1), Tadalafil and Oral Vancomycin in People With Refractory Primary Hepatocellular Carcinoma or Liver Dominant Metastatic Cancer From Colorectal or Pancreatic Cancerstreatment2completed
NCT04177810
Plerixafor and Cemiplimab in Metastatic Pancreatic Cancertreatment2completed
NCT01028495
A Safety and Efficacy Study of RX-0201 Plus Gemcitabine in Metastatic Pancreatic Cancertreatment2completed
NCT00868114
Direct Tumor Injection KLH-Pulsed Dendritic Cells in Unresectable Pancreatic CancerNo drug interventionstreatment2terminated
NCT04769414
Flouro-Gem in Adenocarcinoma of the Pancreas (GEFLUPAN)treatment2completed
NCT04300114
A Study of Maintenance Treatment With Fluzoparib in gBRCA/PALB2 Mutated Pancreatic Cancer Whose Disease Has Not Progressed on First Line Platinum-Based Chemotherapytreatment3terminated
NCT04133155
Retrospective Analysis of 2nd-line Nab-Paclitaxel + Gemcitabine After 1st-line FOLFIRINOX in Pancreatic CancerNot AvailableNot Availablecompleted
NCT05827055
Proglumide and Chemotherapy for Metastatic Pancreatic Cancertreatment2recruiting
NCT05251038
Study of Sotorasib Combined With Chemotherapy for Second Line Treatment of Pancreas Cancertreatment1 / 2withdrawn
NCT01621243
M402 in Combination With Nab-Paclitaxel and Gemcitabine in Pancreatic Cancertreatment1 / 2terminated
NCT03502343
Efficacy and Safety of Modified Nab-Paclitaxel Plus Gemcitabine Chemotherapy for Metastatic Pancreatic Cancertreatment2unknown_status
NCT03627390
BP-C1 in Short-term Treatment of Metastatic Pancreatic Cancertreatment2completed
NCT02080221
BrUOG 292: FOLFOX-A For Metastatic Pancreatic Cancer: A Phase II Brown University Oncology Research Group Trialtreatment2completed
NCT04753879
Multi-agent Low Dose Chemotherapy GAX-CI Followed by Olaparib and Pembro in Metastatic Pancreatic Ductal Cancer.treatment2recruiting
NCT00439179
A Trial of GW572016, Gemcitabine and Oxaliplatin for Metastatic Pancreaticobiliary Cancer SchemaNo drug interventionstreatment1completed
NCT03908333
High Dose Ascorbic Acid and Nanoparticle Paclitaxel Protein Bound and Cisplatin and Gemcitabine (AA NABPLAGEM) in Patients Who Have Metastatic Pancreatic Cancertreatment1 / 2withdrawn
NCT00996333
Study of Gemzar®, Taxotere®, and Xeloda® (GTX) in Patients With Metastatic Pancreatic Cancer (Stage IVB)treatment2completed
NCT01764477
Safety and Efficacy Study of PRI-724 Plus Gemcitabine in Subjects With Advanced or Metastatic Pancreatic Adenocarcinomatreatment1completed
NCT03693677
First Line Metastatic Pancreatic Cancer : 5FU/LV+Nal-IRI, Gemcitabine+Nab-paclitaxel or a Sequential Regimen of 2 Months 5FU/LV+Nal-IRItreatment2active_not_recruiting
NCT01231347
QUILT-2.014: Gemcitabine and AMG 479 in Metastatic Adenocarcinoma of the Pancreastreatment3completed
NCT04665947
First-in-human Study of the Theranostic Pair [68Ga]Ga DOTA-5G and [177Lu]Lu DOTA-ABM-5G in Pancreatic Cancertreatment0recruiting
NCT04672005
Modified FOLFIRINOX Alternated With Biweekly Gemcitabine Plus Nab-Paclitaxel Untreated Pancreatic Cancertreatment2active_not_recruiting
NCT03620461
Gemcitabine and Nabpaclitaxel in Metastatic Pancreatic Carcinoma.Not AvailableNot Availablecompleted
NCT01509911
A Clinical Trial of Anti-Angiogenic Drug Combination Tl-118 for Pancreatic Cancer Patients Who Are Starting Gemcitabine Treatmenttreatment2unknown_status
NCT02570711
Phase 2, Nab Paclitaxel/Gemcitabine Alone and in Combination With ACP-196 in Subjects With Metastatic Pancreatic Cancertreatment2terminated
NCT06361888
A Phase II/III Trial to Evaluate the Efficacy and Safety of Surufatinib Combined With Camrelizumab, Nab-paclitaxel, and Gemcitabine in Metastatic Pancreatic Cancertreatment2 / 3recruiting
NCT05363007
Spleen Irradiation With Nanoliposomal Irinotecan Plus 5-FU and Leucovorin in Metastatic Pancreatic Adenocarcinomatreatment2recruiting
NCT01088815
Hedgehog Inhibitors for Metastatic Adenocarcinoma of the Pancreastreatment2completed
NCT05737615
PET Imaging Using 64Cu-Tz-SarAr and hu5B1-TCO in People With Pancreatic, Colorectal, Bladder Cancer or Cancers With Elevated CA19.9No drug interventionsdiagnostic1recruiting
NCT01461915
Phase 2 Study to Assess the Efficacy & Safety of Gemcitabine + Nab Paclitaxel With or Without Dociparstat in Metastatic Pancreatic Cancer Patientstreatment2terminated
NCT00726037
A Pilot Study, Evaluating the Efficacy of Regulatory T-cell Suppression by Ontak in Metastatic Pancreatic Cancertreatment2terminated
NCT03376659
Durvalumab Plus CV301 With Maintenance Chemotherapy in Metastatic Colorectal or Pancreatic Adenocarcinomatreatment1 / 2terminated
NCT01524575
Gemcitabine and Oxaliplatin in the Management of Metastatic Pancreatic Cancers With Low Expression of ERCC1treatment2withdrawn
NCT05927142
Combining Anti-PD-L1 Immune Checkpoint Inhibitor Durvalumab With TLR-3 Agonist Rintatolimod in Patients With Metastatic Pancreatic Ductal Adenocarcinoma for Therapy Efficacyother1 / 2recruiting
NCT00786006
Randomized Phase II Study of FOLFOX Versus FOLFIRI.3 in Gemcitabine-refractory Pancreatic Cancertreatment2completed
NCT00383149
A Phase II, Trial of Ixabepilone Plus Cetuximab as First Line Therapy for Metastatic Pancreatic Cancertreatment2completed
NCT05346536
Liquid Biopsy and Pancreas Cancer: Detection of AXL(+) CTCs (CTC-AXL-PANC)No drug interventionsotherNot Availableunknown_status
NCT04112836
Pancreatic Cancer Malnutrition and Pancreatic Exocrine Insufficiency in the Course of Chemotherapy in Unresectable Pancreatic CancerNo drug interventionsNot AvailableNot Availableunknown_status
NCT04605913
Nab-Paclitaxel + Cisplatin + Gemcitabine + TTF in pt. w/ Metastatic PACNo drug interventionstreatment1 / 2recruiting
NCT05650918
MesoPher/Mitazalimab-combination Therapy in Metastatic Pancreatic Disease (REACtiVe-2 Trial)other1completed
NCT01608841
The Role of EGFR Mutations in Pancreatic Cancer Patients Receiving Gemcitabine With or Without Erlotinibtreatment2unknown_status
NCT04901741
Olaptesed With Pembrolizumab and Nanoliposomal Irinotecan or Gemcitabine/Nab-Paclitaxel in MSS Pancreatic Cancertreatment2not_yet_recruiting
NCT02975141
Afatinib and Gemcitabine/Nab-paclitaxel in Metastatic Pancreatic Cancerother1unknown_status
NCT04589234
Saltikva for Metastatic Pancreatic Cancertreatment2active_not_recruiting
NCT02184663
Evaluation of an Adapted Physical Activity Program in Patients With Unresectable Pancreatic CancerNo drug interventionsbasic_scienceNot Availableactive_not_recruiting
NCT01077986
Everolimus, Cetuximab and Capecitabine in Patients With Metastatic Pancreatic Cancertreatment1 / 2completed
NCT04327986
Immune Checkpoint Inhibitor M7824 and the Immunocytokine M9241 in Combination With Stereotactic Body Radiation Therapy (SBRT) in Adults With Advanced Pancreas Cancertreatment1 / 2terminated
NCT03697239
High Dose Ascorbic Acid (AA) + Nanoparticle Paclitaxel Protein Bound + Cisplatin + Gemcitabine (AA NABPLAGEM) in Patients Who Have Metastatic Pancreatic Cancertreatment1 / 2withdrawn
NCT04612530
PANFIRE-3 Trial: Assessing Safety and Efficacy of Irreversible Electroporation (IRE) + Nivolumab + CpG for Metastatic Pancreatic Cancertreatment1recruiting
NCT05766748
Study of Effect of Azeliragon in Patients Refractory to Prior Treatment of Metastatic Pancreatic Cancertreatment1 / 2recruiting
NCT06454448
Phase Ib/II Clinical Study of Adebrelimab in Combination With Decitabine, Albumin-bound Paclitaxel, and Gemcitabine for the First-line Treatment of Metastatic Pancreatic Cancertreatment1 / 2recruiting
NCT03415126
A Study of ASN007 in Patients With Advanced Solid TumorsNo drug interventionstreatment1completed
NCT01489865
ABT-888 With Modified FOLFOX6 in Patients With Metastatic Pancreatic Cancertreatment1 / 2unknown_status
NCT03281382
Phase 1 Trial of Interleukin 12 Gene Therapy for Metastatic Pancreatic CancerNo drug interventionstreatment1completed
NCT03250273
A Clinical Trial of Entinostat in Combination With Nivolumab for Patients With Previously Treated Unresectable or Metastatic Cholangiocarcinoma and Pancreatic Adenocarcinomatreatment2completed
NCT03986294
Second Line Treatment With Nal-IRI and S1 in Pancreatic Cancertreatment2unknown_status
NCT01272791
Trial of Gemcitabine With or Without Bavituximab in Patients With Previously Untreated Stage IV Pancreatic Cancertreatment2completed
NCT04789980
Good Choice of pALliative Chemotherapy to Patient With Pancreatic Cancer ; GemcitAbine Therapy vs FOLFORINOX therapYNo drug interventionsNot AvailableNot Availablerecruiting
NCT04101929
Apatinib, Irinotecan and S-1 (ApaIRIS) in Treating Patients With Metastatic Pancreatic Cancer After AG Regimentreatment2unknown_status
NCT03682289
Ceralasertib (AZD6738) Alone and in Combination With Olaparib or Durvalumab in Patients With Solid Tumorstreatment2recruiting
NCT03721744
A Study of GB201 in Combination With Weekly Paclitaxel and Low-dose Gemcitabine in Patients With Pancreatic Cancertreatment2 / 3recruiting
NCT06532344
An Open-label, Uncontrolled Study of ONO-7913 and ONO-4538 in Combination With Modified FOLFIRINOX Therapy, the Standard of Care, as First-line Treatment in Patients With Metastatic Pancreatic Cancertreatment1active_not_recruiting
NCT02863367
A One-Arm Exploratory Clinical Trial of Apatinib Plus Gemcitabine in Patients With Advanced Metastatic Pancreatic Cancertreatment2unknown_status
NCT02827201
FIrst Line Treatment of Metastatic Pancreatic Cancer: Sequential Nab-paclitaxel + Gemcitabine/FOLFIRI.3 VS Nab-paclitaxel + Gemcitabinetreatment2completed
NCT05065801
Efficacy of Gembrax Followed by Folfirinox Versus Folfirinox Alone in First Metastatic Line Pancreatic Cancer PatientsNo drug interventionstreatment2recruiting
NCT03446872
Post Marketing Surveillance Study for ONIVYDE® in South KoreaNot AvailableNot Availablecompleted
NCT01410968
A Feasibility and Safety Study of Vaccination With Poly-ICLC and Peptide-pulsed Dendritic Cells in Patients With Metastatic, Locally Advanced, Unresectable, or Recurrent Pancreatic Adenocarcinomatreatment1completed
NCT00222469
Combination Chemotherapy for 1st Line Treatment of Advanced or Metastatic Pancreatic Cancerprevention2completed
NCT02564146
First-line Treatment of Metastatic Pancreatic Cancer With Nab-paclitaxel and Gemcitabinetreatment2completed
NCT02781012
Project Survival-Prospective Biomarker DiscoveryNo drug interventionsNot AvailableNot Availableunknown_status
NCT06353581
Prophylactic Administration of Neulapeg (Pegteograstim) in Patients With Locally Advanced or Metastatic Pancreatic Cancer Receiving the Modified FOLFIRINOXNo drug interventionsprevention2active_not_recruiting
NCT02077881
Study of IDO Inhibitor in Combination With Gemcitabine and Nab-Paclitaxel in Patients With Metastatic Pancreatic Cancertreatment1 / 2completed
NCT04790695
Single Patient Protocol for an NRG1 Fusion Positive Metastatic Pancreatic Cancer Patient Using Seribantumabtreatment2completed
NCT05380414
Profiling Program of Advanced/Metastatic Pancreatic Cancer PatientsNo drug interventionsscreeningNot Availablerecruiting
NCT05988814
Trial Evaluating the Efficacy and the Safety of FOLFIRINOX3 Treatment in Patients With Unresectable Locally Advanced or Metastatic Pancreatic Cancer in First Line of ChemotherapyNo drug interventionstreatment2recruiting
NCT03189914
RX-3117 in Combination With Abraxane® in Subjects With Metastatic Pancreatic Cancertreatment1 / 2completed
NCT03714555
Disulfiram-Copper Gluconate in Met Pancreas Cancer w Rising CA19-9 on Abraxane-Gemzar, FOLFIRINOX or Gemcitabinetreatment2terminated
NCT06017323
Proglumide With Gemcitabine and Nab-Paclitaxel in PatientsWith Metastatic Pancreatic Ductal Adenocarcinomatreatment1withdrawn
NCT06469138
A Phase 1 Study to Investigate 14C-bemcentinib Following Single Oral Administration in Healthy Male Subjectstreatment1completed
NCT03797443
High Dose Ascorbic Acid (AA) + Nanoparticle Paclitaxel Protein Bound + Cisplatin + Gemcitabine (AA NABPLAGEM) in Patients Who Have Metastatic Pancreatic Cancertreatment1 / 2withdrawn
NCT05657743
A Feasibility and Safety Study of Intratumoral Diffusing Alpha Radiation Emitters for the Treatment of Advanced Pancreatic CancerNo drug interventionstreatmentNot Availablerecruiting
NCT06615830
Organoid-driven Chemotherapy Choice in Metastatic Pancreatic Cancer Patients.No drug interventionstreatment2not_yet_recruiting
NCT02959151
A Study of Chimeric Antigen Receptor T Cells Combined With Interventional Therapy in Advanced Liver MalignancyNo drug interventionstreatment1 / 2unknown_status
NCT04467593
Safety Study of Whole Body Hyperthermia for Advanced CancerNo drug interventionstreatmentNot Availablerecruiting
NCT06076837
The Seven Trial: Exploiting the Unfolded Protein Responsetreatment1not_yet_recruiting
NCT03412799
Study of SBP-101 Combined With Nab-Paclitaxel and Gemcitabine in Pancreatic Cancertreatment1completed
NCT06155136
RWE on Patients With mPDAC Long-term Survival After Treatment With Liposomal IrinotecanNo drug interventionsNot AvailableNot Availableactive_not_recruiting
NCT05047991
Study of Irinotecan Liposome Injection-containing Regimens Versus Nab-paclitaxel Plus Gemcitabine in Patients With Previously Untreated, Metastatic Pancreatic Adenocarcinomatreatment2not_yet_recruiting
NCT03984214
Efficacy and Safety of Dronabinol in the Improvement of Chemotherapy-induced and Tumor-related Symptoms in Advanced Pancreatic Cancertreatment3active_not_recruiting
NCT03504423
Study Evaluating Efficacy and Safety of FFX Versus Combination of CPI-613 With mFFX in Patients With Metastatic Adenocarcinoma of the Pancreastreatment3completed
NCT04667403
Telemedicine in the Management of Pain in Patients With Advanced or Metastatic Pancreatic CancerNo drug interventionssupportive_careNot Availableunknown_status
NCT05254171
Study of Nab-Paclitaxel and Gemcitabine With or Without SBP-101 in Pancreatic Cancertreatment2 / 3recruiting
NCT04469556
Pancreatic Adenocarcinoma Signature Stratification for Treatmenttreatment2active_not_recruiting
NCT04674956
A Prospective, Randomized, Double-blinded, Multi-center Clinical Trial to Evaluate the Efficiency and Safety of Anti-PD1 Antibody (Camrelizumab) Combined With Paclitaxel(Albumin Bound) and Gemcitabine as First-line Therapy in Patients With Metastatic Pancreatic Cancertreatment3recruiting
NCT04338763
RP72 Monotherapy and in Combination With Gemcitabine in Patients With Pancreatic Cancertreatment1recruiting
NCT06030622
Phase 2A Pilot C3 Trial of Recurrent/Refractory Metastatic Advanced Pancreatic Cancerother1 / 2recruiting
NCT04799431
Neoantigen-Targeted Vaccine Combined With Anti-PD-1 Antibody for Patients With Stage IV MMR-p Colon and Pancreatic Ductal Cancertreatment1withdrawn
NCT04116073
INCMGA00012 in Patients With Previously Treated Unresectable or Metastatic Adenosquamous Pancreatic or Ampullary Cancertreatment2recruiting
NCT01652976
Phase II Study of 5-FU, Oxaliplatin Plus Dasatinib in Metastatic Pancreatic Adenocarcinomatreatment2completed
NCT04852367
PanDox: Targeted Doxorubicin in Pancreatic Tumoursbasic_science1withdrawn
NCT04721301
Ipilimumab, Maraviroc and Nivolumab in Advanced Metastatic Colorectal and Pancreatic Cancer the LUMINESCENCE Trialtreatment1completed
NCT01843725
Phase 1 Study Testing the Combination of Aflibercept and Capecitabine in Metastatic Digestive and Breast Cancerstreatment1completed
NCT04907643
Virtual Reality for GI Cancer Pain to Improve Patient Reported OutcomesNo drug interventionssupportive_careNot Availablerecruiting
NCT04835402
Electroporation Potentiated Immunotherapy in Cancertreatment2active_not_recruiting
NCT02109445
Study Of PF-03084014 In Combination With Gemcitabine And Nab-Paclitaxel In Patients With Metastatic Pancreatic Adenocarcinoma Not Previously Treated With Anticancer Therapiestreatment2terminated
NCT04897854
Timing of Start of systemIc Treatment for Asymptomatic Metastasized Pancreatic CancerNo drug interventionstreatment3unknown_status
NCT01586611
A Study to See if hENT1 Testing on Tumour Tissue Can Predict Response to Treatment With Gemcitabine Chemotherapy and if a Different Chemotherapy Called FOLFOX is Better Than Gemcitabine in Metastatic Pancreas Cancertreatment3unknown_status
NCT03126435
EndoTAG-1+GEM vs GEM in Patients With Locally Advanced/Metastatic Pancreatic Adenocarcinoma Failed on FOLFIRINOXtreatment3completed
NCT02885727
Durvalumab Plus "Booster" RT for Metastatic Adenocarcinoma Pancreas Cancer Post Chemotherapy (GCC 1598)treatment2withdrawn