NCT06302621
Pemigatinib + Afatinib in Advanced Refractory Solid Tumors No drug interventions treatment 1 recruiting NCT05867121
A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7496353 in Combination With a Checkpoint Inhibitor With or Without Standard-of-Care Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors No drug interventions treatment 1 recruiting NCT06238479
A Study of LY4101174 in Participants With Recurrent, Advanced or Metastatic Solid Tumors No drug interventions treatment 1 recruiting NCT04393454
Study to Evaluate the Efficacy and Safety of Sirolimus in Subjects With Metastatic, Mismatch Repair Deficient Solid Tumors After Immunotherapy treatment 2 terminated NCT04799054
A Study of TransCon TLR7/8 Agonist With or Without Pembrolizumab in Patients With Advanced or Metastatic Solid Tumors treatment 1 / 2 recruiting NCT05639751
PRT3789 Monotherapy and in Combo w/Docetaxel in Participants w/Advanced or Metastatic Solid Tumors w/SMARCA4 Mutation treatment 1 recruiting NCT04447651
Patient Response to Immunotherapy Using Spliceosome Mutational Markers (PRISMM) No drug interventions Not Available Not Available active_not_recruiting NCT04977453
GI-101 as a Single Agent or in Combination With Pembrolizumab, Lenvatinib or Local Radiotherapy in Advanced Solid Tumors treatment 1 / 2 recruiting NCT05828277
A Phase 1 Study to Assess the Effect of Hepatic Impairment on the Pharmacokinetics of Repotrectinib in Advanced Cancer Patients treatment 1 withdrawn NCT04319198
Rollover Study in Participants With Metastatic Solid Tumors Benefiting From Therapy With Sacituzumab Govitecan-hziy treatment 4 enrolling_by_invitation NCT04761198
A Study of Etigilimab and Nivolumab in Subjects With Locally Advanced or Metastatic Tumors. basic_science 1 / 2 completed NCT06440005
A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors No drug interventions treatment 1 recruiting NCT05071183
A Study of Repotrectinib in Combination With Other Anticancer Therapies for the Treatment of Subjects With KRAS-Mutant Solid Tumors treatment 1 / 2 terminated NCT05673928
A Phase II Study of Tucatinib and Ado-trastuzumab Emtansine (T-DM1) in Patients With HER2-positive Metastatic Solid Tumors and Metastases to Brain (TUCATEMEB) treatment 2 recruiting NCT06244771
A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors No drug interventions treatment 1 / 2 recruiting NCT05471271
IL-2 PET Imaging in Advanced Solid Tumours No drug interventions diagnostic Not Available recruiting NCT01393509
The First-in-human Phase I Trial of PU-H71 in Patients With Advanced Malignancies treatment 1 completed NCT05694715
Combination Therapy in Cancers With Mutations in DNA Repair Genes treatment 1 recruiting NCT05919537
Study of an Anti-HER3 Antibody, HMBD-001, With or Without Chemotherapy in Patients With Solid Tumors Harboring an NRG1 Fusion or HER3 Mutation treatment 1 recruiting NCT06235437
Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ASD141 No drug interventions treatment 1 not_yet_recruiting NCT04419532
A Study Evaluating DS-1055a in Participants With Relapsed or Refractory Locally Advanced or Metastatic Solid Tumors No drug interventions treatment 1 recruiting NCT04137900
Safety, Tolerability and Pharmacokinetics of a Monoclonal Antibody Specific to B-and T-Lymphocyte Attenuator (BTLA) as Monotherapy and in Combination With an Anti-PD1 Monoclonal Antibody for Injection in Subjects With Advanced Malignancies treatment 1 recruiting NCT04294875
Phase I, FIH, MTD for MPT0B640, Multi-centre, Open-label, Subject With Locally Advanced or Metastatic Solid Malignancies treatment 0 withdrawn NCT05824975
A Study to Evaluate the Safety and Therapeutic Activity of GI-102 in Patients With Advanced Solid Tumors No drug interventions treatment 1 / 2 recruiting NCT05769075
A Study of TY-2136b in Patients With Advanced Solid Tumors Harboring ALK, ROS1 or NTRK1-3 Alterations No drug interventions treatment 1 recruiting NCT05898399
Study of ART6043 in Advanced/Metastatic Solid Tumors Patients treatment 1 / 2 recruiting NCT01390818
Trial of MEK Inhibitor and PI3K/mTOR Inhibitor in Subjects With Locally Advanced or Metastatic Solid Tumors treatment 1 completed NCT04914117
A Study of RC118 in Patients With Locally Advanced Unresectable/Metastatic Solid Tumours treatment 1 completed NCT04892017
A Phase 1/2 Study of DCC-3116 in Patients With RAS/MAPK Pathway Mutant Solid Tumors treatment 1 / 2 recruiting NCT05862324
TAC T-cells for the Treatment of Claudin 18.2 Positive Solid Tumors (TACTIC-3) No drug interventions treatment 1 / 2 recruiting NCT03263416
Study Evaluating Treatment Adherence in Patients Treated With Oral Targeted Therapy in Oncology Supported by a Dedicated and Coordinated Follow-up Compared to Standard Follow-up. No drug interventions health_services_research Not Available completed NCT04579757
Surufatinib in Combination With Tislelizumab in Subjects With Advanced Solid Tumors treatment 1 / 2 active_not_recruiting NCT05384626
A Study of NVL-655 in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1) treatment 1 / 2 recruiting NCT06540066
A Study of BGB-B3227 Alone and in Combination With Tislelizumab in Participants With Advanced or Metastatic Solid Tumors treatment 1 not_yet_recruiting NCT05268666
A Study of Orally Administered JBI-802, an LSD1/HDAC6 Inhibitor, in Patients With Advanced Solid Tumors treatment 1 / 2 recruiting NCT05480865
SHP2 Inhibitor BBP-398 in Combination With Sotorasib in Patients With Advanced Solid Tumors and a KRAS-G12C Mutation treatment 1 recruiting NCT04986865
A Study ATG-101 in Patients With Metastatic/Advanced Solid Tumors and Mature B-cell Non-Hodgkin Lymphomas treatment 1 recruiting NCT04849273
A Study of TPX-0131, a Novel Oral ALK Tyrosine Kinase Inhibitor, in Patients With ALK+ Advanced or Metastatic NSCLC treatment 1 terminated NCT05631327
A JZP341 Study in Adult Participants With Advanced or Metastatic Solid Tumors No drug interventions treatment 1 terminated NCT06163391
A Study to Assess Safety and Efficacy of SOT201 in Patients With Advanced/Metastatic Cancer No drug interventions treatment 1 recruiting NCT04161391
Study of TPX-0046, A RET/SRC Inhibitor in Adult Subjects With Advanced Solid Tumors Harboring RET Fusions or Mutations No drug interventions treatment 1 / 2 terminated NCT05688280
Intratumoral Injection of IP-001 Following Thermal Ablation in Patients With CRC, NSCLC, and STS No drug interventions treatment 1 / 2 recruiting NCT00997529
Mini Allo Stem Cell Transplantation for the Treatment of Solid Tumors No drug interventions treatment Not Available completed NCT05118789
A Study of NVL-520 in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearrangement (ARROS-1) No drug interventions treatment 1 / 2 recruiting NCT04614740
The Phase I/Phase II Clinical Study of VC004 in Patients With Localized Advanced/Metastatic Solid Tumors No drug interventions treatment 1 / 2 recruiting NCT05872867
Study of WM-A1-3389 in Participants With Advanced or Metastatic Solid Tumors and Non-Small Cell Lung Cancer (MK-3475-E90/KEYNOTE-E90) treatment 1 recruiting NCT05837767
A Study of Radiation Therapy to Treat Solid Tumor Cancer That Has Spread to Soft Tissue No drug interventions treatment Not Available recruiting NCT05875168
First-in-Human Study of DS-3939a in Participants With Advanced Solid Tumors No drug interventions treatment 1 / 2 recruiting NCT00611468
Phase I, Dosage-finding and PK Study of IV Topotecan and Erlotinib With Refractory Solid Tumors treatment 1 completed NCT06465069
A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors No drug interventions treatment 1 recruiting NCT05678010
A Study of AZD1390 and Stereotactic Body Radiotherapy (SBRT) for People With Metastatic Solid Tumor Cancer No drug interventions treatment 1 recruiting NCT04383210
Study of Seribantumab in Adult Patients With NRG1 Gene Fusion Positive Advanced Solid Tumors treatment 2 active_not_recruiting NCT04585750
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE) treatment 1 / 2 recruiting NCT05983523
A Study of PEP07 (Checkpoint Kinase 1 Inhibitor) in Patients With Advanced or Metastatic Solid Tumors No drug interventions treatment 1 not_yet_recruiting NCT05828303
A Phase 1 Study to Evaluate the Potential Drug Interactions Between Repotrectinib and Metformin, Digoxin, and Rosuvastatin in Patients With Advanced Solid Tumors treatment 1 not_yet_recruiting NCT05279690
Pilot Trial of Colchicine in Urothelial Cancer and Other Solid Tumors treatment 1 recruiting NCT04602702
Hyper-Personalized Medicine Using Patient Derived Xenografts (PDXovo) for Metastatic Solid Tumors No drug interventions Not Available Not Available unknown_status NCT03284502
HM95573 in Combination With Either Cobimetinib or Cetuximab in Patients With Locally Advanced or Metastatic Solid Tumors treatment 1 active_not_recruiting NCT06415487
ACE2016 in Adult Subjects With Locally Advanced or Metastatic Solid Tumors Expressing Epidermal Growth Factor Receptor (EGFR) treatment 1 not_yet_recruiting NCT04471987
Safety and Early Signs of Efficacy of IL12-L19L19. No drug interventions treatment 1 recruiting NCT06577987
Safety/Efficacy Study of CID-078 in Patients With Advanced Solid Tumor Malignancies No drug interventions treatment 1 recruiting NCT05126433
Lurbinectedin Monotherapy in Participants With Advanced or Metastatic Solid Tumors (EMERGE-201) treatment 2 completed NCT06521554
A Study of NVL-330 in Patients With Advanced or Metastatic HER2-altered NSCLC (HEROEX-1) No drug interventions treatment 1 recruiting NCT06560645
A Study of PRT7732, an Oral SMARCA2 Degrader, in Patients With Advanced or Metastatic Solid Tumors With a SMARCA4 Mutation No drug interventions treatment 1 not_yet_recruiting NCT05935098
A Study of BGB-A3055, Alone and in Combination With Tislelizumab in Participants With Selected Advanced or Metastatic Solid Tumors treatment 1 recruiting NCT05028478
A Study of CN202 in Adult Subjects With Locally Advanced or Metastatic Solid Tumors or Hematologic Malignancies No drug interventions treatment 1 / 2 unknown_status NCT05232409
Determine Safety & Recommended Phase 2 Dosing of Zeaxanthin Alone or in Combination w/Pembrolizumab in Patients With Metastatic Cancer treatment 1 recruiting NCT05081609
A Study to Investigate Safety and Tolerability of TransCon IL-2 β/γ Alone or in Combination With Pembrolizumab and/or Chemotherapy or TransCon TLR7/8 Agonist in Adult Participants With Locally Advanced or Metastatic Solid Tumor Malignancies treatment 1 / 2 recruiting NCT05259709
A Study of ImmunoPet Imaging Using 89Zr-DFO-REGN5054 in Adult Participants With Solid Cancers Treated With Cemiplimab treatment 1 recruiting NCT06561685
A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors No drug interventions treatment 1 not_yet_recruiting NCT04706715
LAG3 PET Imaging in Advanced Solid Tumors other 1 / 2 active_not_recruiting NCT05076552
A Study to Assess the Safety, Pharmacokinetics, and Antitumor Activity of Oral TACH101 in Participants With Advanced or Metastatic Cancer No drug interventions treatment 1 active_not_recruiting NCT05863052
Analyzing Clinical Outcomes and Genomic Data of American Indian Patient Population No drug interventions Not Available Not Available active_not_recruiting NCT05530200
PRaG Regimens Rechallenge for Patients With Resistance to PD1/PD-L1 Inhibitors in Refractory Advanced Solid Tumors. No drug interventions treatment 2 not_yet_recruiting NCT05474859
Subjects With Advanced or Metastatic Solid Tumor Malignancies No drug interventions treatment 1 not_yet_recruiting NCT04474470
A Study to Evaluate NT219 Alone and in Combination With ERBITUX® (Cetuximab) in Adults With Advanced Solid Tumors and Head and Neck Cancer treatment 1 / 2 active_not_recruiting NCT06545942
Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors treatment 1 recruiting NCT06266299
A Study of KK2269 in Adult Participants With Solid Tumors treatment 1 recruiting NCT06270706
A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors treatment 1 recruiting NCT06427941
A Phase 1 Study of BGB-B2033, Alone or in Combination With Tislelizumab, in Participants With Advanced or Metastatic Solid Tumors treatment 1 not_yet_recruiting NCT05004116
A Study of Repotrectinib in Combination With Chemotherapy in Children and Young Adults With Solid Tumor Cancer treatment 1 / 2 recruiting NCT05103358
Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1) treatment 2 active_not_recruiting NCT02133625
A Study of Pioglitazone and Carboplatin in Patients With Advanced Solid Tumors treatment 1 completed NCT05717348
A Study of ES014 in Patients With Locally Advanced or Metastatic Solid Tumours No drug interventions treatment 1 recruiting NCT05809557
EMR Chemotoxicity Risk Calculator To Decrease Chemotherapy Toxicity No drug interventions prevention Not Available completed NCT03964727
Study of Sacituzumab Govitecan in Participants With Metastatic Solid Tumors treatment 2 active_not_recruiting NCT04761744
A Phase II Study of Nivolumab in Patients With Genetic Alterations in DNA Damage Repair and Response Who Progressed After Standard Treatment for Metastatic Solid Cancers treatment 2 unknown_status NCT06548672
A Study to Assess the Safety, Pharmacokinetics, and Antitumor Activity of BC3195 in Patients With Advanced or Metastatic Cancer No drug interventions treatment 1 recruiting NCT05435768
PraG With RANKL Inhibitor for the Treatment of Advanced Multiple Metastatic Solid Tumors No drug interventions Not Available Not Available not_yet_recruiting NCT05479812
Dose Escalation Study of WTX-124 as Monotherapy and in Combination With Pembrolizumab (Pembro) in Patients With Selected Advanced or Metastatic Solid Tumors No drug interventions treatment 1 recruiting NCT05385081
PREcision Medicine in Cancer in Odense, Denmark No drug interventions diagnostic Not Available unknown_status NCT05856981
Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors No drug interventions treatment 1 recruiting NCT06253195
BGB-43395 Alone or as Part of Combination Therapies in Chinese Participants With HR+/HER2- Breast Cancer and Other Advanced Solid Tumors No drug interventions treatment 1 recruiting NCT04801095
A Phase I Study of WM-S1-030 in Patients With Advanced Solid Tumors No drug interventions treatment 1 recruiting NCT06171750
Phase I Study of ANK-101 in Advanced Solid Tumors No drug interventions treatment 1 recruiting NCT06108050
JZP898 Intravenous Infusion as Monotherapy and Combination With Pembrolizumab in Adults With Advanced/Metastatic Solid Tumors No drug interventions treatment 1 recruiting NCT04898543
QUILT-3.076: Study of Autologous M-CENK in Subjects With Locally Advanced or Metastatic Solid Tumors No drug interventions treatment 1 recruiting NCT05490043
A Trial of ATG-101 in Patients With Metastatic/Advanced Solid Tumors and Mature B-cell Non-Hodgkin Lymphomas No drug interventions treatment 1 recruiting NCT01976143
A Study in Cancer Patients to Evaluate the Effect of a Single Dose of NKTR-102 (Etirinotecan Pegol) on the QTc Interval and to Assess Pharmacokinetics and Safety No drug interventions treatment 1 completed NCT02045602
Phase I Dose Escalation Study of Intravenous VCN-01 With or Without Gemcitabine and Abraxane® in Patients With Advanced Solid Tumors No drug interventions treatment 1 completed NCT02228811
A Study of DCC-2701 in Participants With Advanced Solid Tumors treatment 1 terminated NCT00148993
Allogeneic Tumor Cell Vaccination in Patients With Solid Tumors No drug interventions Not Available 1 / 2 withdrawn NCT06585488
A First-in-human Study of BGB-53038, a Pan-KRAS Inhibitor, Alone or in Combinations in Participants with Advanced or Metastatic Solid Tumors with KRAS Mutations or Amplification No drug interventions treatment 1 not_yet_recruiting NCT02235688
Study to Investigate the Safety and Activity of Aldoxorubicin Plus Gemcitabine in Subjects With Metastatic Solid Tumors treatment 1 completed NCT03388632
Recombinant Interleukin-15 in Combination With Checkpoint Inhibitors Nivolumab and Ipilimumab in People With Refractory Cancers treatment 1 recruiting NCT00149019
Immunotherapy of Cancer Using Donor Lymphocytes Labelled With In-vitro Bispecific Antibodies. No drug interventions treatment 2 withdrawn NCT06031441
A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7566802 as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors treatment 1 recruiting NCT05836324
A Study to Evaluate the Safety of INCA33890 in Participants With Advanced or Metastatic Solid Tumors No drug interventions treatment 1 recruiting NCT03093116
A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements treatment 1 / 2 recruiting NCT00159016
Role of Glivec in Patients With Tumor Cells Positive for C-kit or PDGFR; a Multi Center Study. treatment 2 withdrawn NCT05487235
A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-1971 in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors treatment 1 active_not_recruiting NCT03427320
Imaging of Advanced Tumours Using [131]I-IAZA No drug interventions other 1 / 2 withdrawn NCT03993873
Study of TPX-0022 in Patients With Advanced NSCLC, Gastric Cancer or Solid Tumors Harboring Genetic Alterations in MET treatment 1 / 2 active_not_recruiting NCT05853367
Study of MK-0472 in Participants With Advanced/Metastatic Solid Tumors (MK-0472-001) treatment 1 recruiting NCT00878423
Study to Assess the Safety of Escalating Doses of AT13387 in Patients With Metastatic Solid Tumors basic_science 1 completed NCT00827203
A Safety Study to Determine the Maximum Tolerated Dose of Elesclomol Sodium in Patients With Solid Tumors No drug interventions treatment 1 suspended NCT03523390
Phase I/Ib Multiple Ascending Dose Study in China treatment 1 completed NCT04695847
M1231 in Participants With Solid Tumors No drug interventions treatment 1 completed NCT00793897
Multiple Dose Study In Cancer Patients: Safety and Tolerability of BMS-754807 in Combination With Paclitaxel and Carboplatin in Patients With Advanced or Metastatic Solid Tumors treatment 1 completed NCT03646071
A Study of RX108 in Patients With Locally Advanced or Metastatic Solid Tumors No drug interventions treatment 1 unknown_status NCT04457778
First in Human Study of M6223 treatment 1 completed NCT00670488
Dose Escalation Study With MK-2206 in Patients With Locally Advanced or Metastatic Solid Tumors (MK-2206-002) treatment 1 completed NCT02281409
Safety, Tolerability, and Immunoregulatory Activity of Mogamulizumab (KW-0761) in Subjects With Advanced and/or Metastatic Solid Tumors treatment 1 / 2 completed NCT01928459
Phase 1b Trial of BGJ398/BYL719 in Solid Tumors treatment 1 completed NCT01449370
Dose Escalation Study of TAK-117 (MLN1117) in Subjects With Advanced Cancer treatment 1 completed NCT05494918
First-In-Human Study in Subjects With Advanced or Metastatic Solid Malignant Tumors No drug interventions treatment 1 recruiting NCT01847118
A Phase Ia, Dose Escalation Study of Humanized Anti-VEGF Monoclonal Antibody (Sevacizumab) Injection in Patients With Advanced or Metastatic Solid Tumors No drug interventions treatment 1 unknown_status NCT03809624
Study of INBRX-105 and INBRX-105 With Pembrolizumab in Patients With Solid Tumors Including Head and Neck Cancer treatment 1 active_not_recruiting NCT05605496
NP137 Clinical and Biological Activities Assessment in Patients With Advanced/Metastatic Solid Tumors Treated by Standard Anti PD-1/PD-L1 Immunotherapies No drug interventions treatment 2 recruiting NCT01543763
Pazopanib in Combination With PCI-24781 in Patients With Metastatic Solid Tumors treatment 1 active_not_recruiting NCT03403725
MEN1309 I.v. Infusion in Pts With CD205-positive Metastatic Solid Tumors and Relapsed or Refractory NHL Ph I Study No drug interventions treatment 1 terminated NCT03910530
A Study of INCMGA00012, INCB001158, and the Combination in Japanese Participants With Advanced Solid Tumors treatment 1 completed NCT03854227
A Dose Escalation Study Of PF-06939999 In Participants With Advanced Or Metastatic Solid Tumors treatment 1 terminated NCT03573544
This Study is to Evaluate Safe and Effective Treatment Dose of OBI-888 in Patients With Locally Advanced or Metastatic Solid Tumors. treatment 1 / 2 terminated NCT04010240
A Retrospective Study to Determine the Incidence of NTRK Fusions. NTRK Study No drug interventions Not Available Not Available completed NCT02097810
Study of Oral RXDX-101 in Adult Patients With Locally Advanced or Metastatic Cancer Targeting NTRK1, NTRK2, NTRK3, ROS1, or ALK Molecular Alterations. No drug interventions treatment 1 completed NCT04094610
A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations No drug interventions treatment 1 / 2 recruiting NCT03893955
A Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ABBV-927 With ABBV-368, Budigalimab (ABBV-181) and/or Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors No drug interventions treatment 1 active_not_recruiting NCT03802123
⁸⁹Zr-Df-IAB22M2C (CD8 PET Tracer) for PET/CT in Patients With Metastatic Solid Tumors No drug interventions diagnostic 2 completed NCT03059823
A Phase 1 Study of INCMGA00012 in Patients With Advanced Solid Tumors No drug interventions treatment 1 completed NCT04134312
A Phase 1 Open Label Trial of Intravenous Administration of MVA-BN-Brachyury Vaccine in Patients With Advanced Cancer No drug interventions treatment 1 completed NCT04167137
Safety and Tolerability of SYNB1891 Injection Alone or in Combination With Atezolizumab in Adult Participants treatment 1 terminated NCT03087591
APN401 in Treating Patients With Recurrent or Metastatic Pancreatic Cancer, Colorectal Cancer, or Other Solid Tumors That Cannot Be Removed by Surgery No drug interventions treatment 1 completed