complicated Urinary Tract Infection caused by Escherichia Coli (DBCOND0093839)

Identifiers

Synonyms

Complicated UTI caused by Escherichia coli

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Ciprofloxacin	A second generation fluoroquinolone used to treat various susceptible bacterial infections.	DNA gyrase subunit Atarget DNA topoisomerase 4 subunit Atarget DNA topoisomerase 2-alphatarget Cytochrome P450 1A2enzyme Cytochrome P450 3A4enzyme Cytochrome P450 3A5enzyme Cytochrome P450 3A7enzyme ATP-dependent translocase ABCB1transporter Voltage-gated inwardly rectifying potassium channel KCNH2target DNA gyrase subunit Atarget DNA topoisomerase 4 subunit Atarget DNA topoisomerase 4 subunit Btarget DNA gyrase subunit Atarget Multidrug resistance protein MdtKtarget Gyrase Atarget DNA gyrase subunit Atarget Multidrug and toxin extrusion protein 1transporter Multidrug and toxin extrusion protein 2transporter Albumincarrier Thymidylate synthasetarget DNA gyrase subunit Btarget
Vaborbactam	A beta lactamase inhibitor used to treat complicated urinary tract infections.	Beta-lactamasetarget Carbapenem-hydrolyzing beta-lactamase KPCtarget Beta-lactamasetarget Beta-lactamase CTX-Mtarget Beta-lactamasetarget Beta-lactamase SHV-1target Beta-lactamase TEMtarget Beta-lactamasetarget Beta-lactamasetarget Beta-lactamasetarget

Clinical Trials

Not Available