Ciprofloxacin

DB00537ApprovedInvestigationalSmall moleculeAnti-Bacterial AgentsFluoroquinolone AntibacterialQuinolone AntimicrobialQuinolones

Ciprofloxacin is a second generation fluoroquinolone used to treat various susceptible bacterial infections. Ciprofloxacin is a second generation fluoroquinolone that has spawned many derivative antibiotics.

Chemical structure of Ciprofloxacin
Mechanism
Curator reviewed · 3 references
Primary indication
Ciprofloxacin is only indicated in infections caused by susceptible bacteria.Curator reviewed · 63 structured indications
Formula / weight
C17H18FN3O3 · 331.3415 g/mol (avg)
First approval
Canada, 1995 · United States, 1987
Code names
BAY-Q-3939 · J01MA02
Brand names
  • Cetraxal
  • Ciloxan
  • Cipro
  • Cipro HC
  • Ciprodex
  • Ciprofloxacin
  • Otiprio
  • Otixal
  • Otovel
  • Proquin

Resolves to

Compound
UNII5E8K9I0O4UCAS85721-33-1ChEMBLCHEMBL8ChEBI192484PubChem4011971KEGGD00186
Clinical / RWD
RxNorm2551ATCJ01MA02ATCJ01RA10ATCJ01RA11PharmGKBPA449009
Structure
InChIKeyMYSWGUAQZAJSOK-UHFFFAOYSA-NSMILESOC(=O)C1=CN(C2CC2)C2=CC(N3CCNCC3)=C(F)C=C2C1=O
Targets
P43702parCP43700gyrAP20831gyrAP0A0K8gyrBP12461TMP1P11388TOP2AQ12809KCNH2P0AES4gyrA+5 more
Transporters
P08183ABCB1Q96FL8SLC47A1Q86VL8SLC47A2

What you can answer from here — as of September 23, 2026

13Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
3TransportersSubstrate / inhibitor direction, not just membership
Listed above
2,059Drug interactionsStructured to mechanism, not free text
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302Clinical trialsPhase, status and sponsor resolved per trial
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63Structured indicationsCondition, population, route and combination as fields, not prose
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6ContraindicationsEach with its own population and attribute set
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2,187Marketed productsAcross 11 countries and 466 labellers
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7ATC codesIncluding every combination product, plus 43 drug categories
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75+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Ciprofloxacin, and which of those have an active Phase 3 trial?

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