Fibrinolytic Hemorrhage, Acquired (DBCOND0131712)

Identifiers

Synonyms

Consumption coagulopathy / Coagulopathy, Consumption / Purpura Fulminans / Afibrinogenemia, acquired / DIC / Consumptive coagulopathy / Disseminated intravascular coagulation / Defibrination syndrome / Disseminated intravascular coagulation (disorder) / Purpura fulminans (disorder) / Acquired afibrinogenaemia / Acquired afibrinogenemia (disorder) / Acquired afibrinogenemia

Associated Data

Indicated Drugs and Targets

Drug	Description	Targets
Heparin	An anticoagulant indicated for thromboprophylaxis and to treat thrombosis associated with a variety of conditions such as pulmonary embolism and atrial fibrillation.	Antithrombin-IIItarget Coagulation factor Xtarget P-selectintarget Heparanaseenzyme Fibroblast growth factor receptor 4target Fibroblast growth factor 4target Fibroblast growth factor 19target Fibroblast growth factor receptor 1target Fibroblast growth factor 1target Fibroblast growth factor receptor 2target Fibroblast growth factor 2target Platelet factor 4target Hepatocyte growth factortarget
Protein C	A medication used to treat protein C deficiency leading to purpura fulminans or coumarin-induced skin necrosis.	Coagulation factor Vtarget Coagulation factor VIIItarget

Clinical Trials

Identifier	Title	Drug(s)	Purpose	Phase	Status
NCT04515420	The Influence of Noradrenaline on Coagulation and Fibrinolysis in Severe Isolated Brain Injury	Norepinephrine	Not Available	Not Available	unknown_status
NCT03782025	Effect of Vitamin K in Critically Ill Patients	Phylloquinone	Not Available	Not Available	completed
NCT04520282	Hemostatic Variables In Snakebite Study	No drug interventions	Not Available	Not Available	completed
NCT03859154	Waveform Analysis In Snakebite Victims With Hematotoxicity	No drug interventions	Not Available	Not Available	completed
NCT05391412	Effect of Prophylactic Fibrinogen Concentrate In Scoliosis Surgery	Fibrinogen human	prevention	4	recruiting
NCT03216577	Outcomes of Purpura FULminans in Adults - The hOPeFUL Study	No drug interventions	Not Available	Not Available	completed