refractory Classical Hodgkin's Lymphoma (DBCOND0144296)
Identifiers
- Synonyms
- Classical Hodgkin lymphoma refractory / Refractory Classical Hodgkin Lymphoma / Refractory Classic Hodgkin Lymphoma / Refractory Hodgkin lymphoma (disorder) / Hodgkin's disease NOS refractory / Hodgkin's disease refractory
Associated Data
- Indicated Drugs and Targets
Drug Description Targets Pembrolizumab A PD-1 blocking antibody used to treat various types of cancer, including metastatic melanoma, non small-cell lung cancer, cervical cancer, head and neck cancer, and Hodgkin's lymphoma.- Clinical Trials
Identifier Title Drug(s) Purpose Phase Status NCT06504394 A Study to Evaluate the Safety and Efficacy of Pembrolizumab (MK-3475) Coformulated With Hyaluronidase (MK-3475A) in Participants With Relapsed or Refractory Classical Hodgkin Lymphoma (rrcHL) or Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma (rrPMBCL)(MK-3475A-F65) treatment 2 recruiting NCT04074746 Modified Immune Cells (AFM13-NK) and A Monoclonal Antibody (AFM13) in Treating Patients With Recurrent or Refractory CD30 Positive Hodgkin or Non-Hodgkin Lymphomas treatment 1 / 2 active_not_recruiting NCT01896999 Brentuximab Vedotin and Nivolumab With or Without Ipilimumab in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma treatment 1 / 2 active_not_recruiting NCT05162976 CC-486 and Nivolumab for the Treatment of Hodgkin Lymphoma Refractory to PD-1 Therapy or Relapsed treatment 1 active_not_recruiting NCT05711628 A Trial Comparing Chemotherapy Versus Novel Immune Checkpoint Inhibitor (Pembrolizumab) Plus Chemotherapy in Treating Relapsed/Refractory Classical Hodgkin Lymphoma treatment 3 withdrawn NCT05518318 GLS-010 Monotherapy Versus Chemotherapy in Patients With Relapsed or Refractory Classical Hodgkin's Lymphoma (R/R cHL) treatment 3 not_yet_recruiting NCT03150329 Pembrolizumab and Vorinostat in Patients With Relapsed or Refractory DLBCL, FCL or HL. treatment 1 active_not_recruiting NCT06190067 Azacitidine Plus PD-1 Therapy for R/R Hodgkin Lymphoma treatment 2 recruiting NCT04788043 Study of Magrolimab and Pembrolizumab in Relapsed or Refractory Classic Hodgkin Lymphoma treatment 2 active_not_recruiting NCT02408861 Nivolumab and Ipilimumab in Treating Patients With HIV Associated Relapsed or Refractory Classical Hodgkin Lymphoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery treatment 1 recruiting NCT02595866 Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancer treatment 1 completed NCT05039073 Brentuximab Vedotin and Nivolumab for the Treatment of Relapsed/Refractory Classic Hodgkin Lymphoma Previously Treated With Brentuximab Vedotin or Checkpoint Inhibitors treatment 2 recruiting NCT00967369 Combination Chemotherapy With or Without Bortezomib in Treating Patients With Classical Hodgkin Lymphoma That Has Returned or Does Not Respond to Prior Treatment. treatment 2 completed