refractory Classical Hodgkin's Lymphoma (DBCOND0144296)

Identifiers

Synonyms
Classical Hodgkin lymphoma refractory / Refractory Classical Hodgkin Lymphoma / Refractory Classic Hodgkin Lymphoma / Refractory Hodgkin lymphoma (disorder) / Hodgkin's disease NOS refractory / Hodgkin's disease refractory

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Pembrolizumab
A PD-1 blocking antibody used to treat various types of cancer, including metastatic melanoma, non small-cell lung cancer, cervical cancer, head and neck cancer, and Hodgkin's lymphoma.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT06504394
A Study to Evaluate the Safety and Efficacy of Pembrolizumab (MK-3475) Coformulated With Hyaluronidase (MK-3475A) in Participants With Relapsed or Refractory Classical Hodgkin Lymphoma (rrcHL) or Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma (rrPMBCL)(MK-3475A-F65)treatment2recruiting
NCT04074746
Modified Immune Cells (AFM13-NK) and A Monoclonal Antibody (AFM13) in Treating Patients With Recurrent or Refractory CD30 Positive Hodgkin or Non-Hodgkin Lymphomastreatment1 / 2active_not_recruiting
NCT01896999
Brentuximab Vedotin and Nivolumab With or Without Ipilimumab in Treating Patients With Relapsed or Refractory Hodgkin Lymphomatreatment1 / 2active_not_recruiting
NCT05162976
CC-486 and Nivolumab for the Treatment of Hodgkin Lymphoma Refractory to PD-1 Therapy or Relapsedtreatment1active_not_recruiting
NCT05711628
A Trial Comparing Chemotherapy Versus Novel Immune Checkpoint Inhibitor (Pembrolizumab) Plus Chemotherapy in Treating Relapsed/Refractory Classical Hodgkin Lymphomatreatment3withdrawn
NCT05518318
GLS-010 Monotherapy Versus Chemotherapy in Patients With Relapsed or Refractory Classical Hodgkin's Lymphoma (R/R cHL)treatment3not_yet_recruiting
NCT03150329
Pembrolizumab and Vorinostat in Patients With Relapsed or Refractory DLBCL, FCL or HL.treatment1active_not_recruiting
NCT06190067
Azacitidine Plus PD-1 Therapy for R/R Hodgkin Lymphomatreatment2recruiting
NCT04788043
Study of Magrolimab and Pembrolizumab in Relapsed or Refractory Classic Hodgkin Lymphomatreatment2active_not_recruiting
NCT02408861
Nivolumab and Ipilimumab in Treating Patients With HIV Associated Relapsed or Refractory Classical Hodgkin Lymphoma or Solid Tumors That Are Metastatic or Cannot Be Removed by Surgerytreatment1recruiting
NCT02595866
Testing the Addition of an Experimental Medication MK-3475 (Pembrolizumab) to Usual Anti-Retroviral Medications in Patients With HIV and Cancertreatment1completed
NCT05039073
Brentuximab Vedotin and Nivolumab for the Treatment of Relapsed/Refractory Classic Hodgkin Lymphoma Previously Treated With Brentuximab Vedotin or Checkpoint Inhibitorstreatment2recruiting
NCT00967369
Combination Chemotherapy With or Without Bortezomib in Treating Patients With Classical Hodgkin Lymphoma That Has Returned or Does Not Respond to Prior Treatment.treatment2completed