Lung Cancer, Nonsmall Cell, Stage IIIA (DBCOND0150709)

Identifiers

Synonyms
Non-small Cell Lung Cancer Stage IIIA / IIIA Stage Non-small Cell Lung Cancer / Non Small Cell Lung Cancer Stage IIIA / Stage IIIA Non-Small Cell Lung Cancer / Stage IIIA Non Small Cell Lung Cancer / Lung cancer non-small cell stage IIIA

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Atezolizumab
A monoclonal antibody used to treat advanced or metastatic urothelial carcinoma with disease progression during or up to 12 months after platinum-containing chemotherapy.
Gemcitabine
A nucleoside metabolic inhibitor used as adjunct therapy in the treatment of certain types of ovarian cancer, non-small cell lung carcinoma, metastatic breast cancer, and as a single agent for pancreatic cancer.
Pembrolizumab
A PD-1 blocking antibody used to treat various types of cancer, including metastatic melanoma, non small-cell lung cancer, cervical cancer, head and neck cancer, and Hodgkin's lymphoma.
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT05497973
Psychosocial eHealth in Advanced Lung CancerNo drug interventionssupportive_careNot Availablerecruiting
NCT03396185
Icotinib as Consolidation Therapy After Chemoradiotherapy in EGFR-Mutant Stage IIIA-IIIB Non-small Cell Lung Cancertreatment2unknown_status
NCT01991418
Early Warning Study of Serum Thioredoixn Reductase Activity in Excised Non-small Cell Lung Cancers (EWSOTRILC)No drug interventionsNot AvailableNot Availablecompleted
NCT02974426
To Evaluate the Optimal Timing of Postoperative Radiotherapy in Patients With IIIA(N2) Non-Small Cell Lung Cancertreatment3terminated
NCT05732974
A Machine Learning Approach to Identify Patients With Resected Non-small-cell Lung Cancer With High Risk of RelapseNo drug interventionsNot AvailableNot Availablerecruiting
NCT04455594
Almonertinib Vs. Erlotinib/Chemotherapy for Neo-adjuVant Treatment of Stage IIIA-N2 EGFR-mutated NSCLCtreatment2not_yet_recruiting
NCT02977169
To Evaluate the Role of Postoperative Radiotherapy in Patients With IIIA(N2) Non-Small Cell Lung Cancertreatment2unknown_status
NCT01410214
Erlotinib Versus Vinorelbine/Cisplatin as Adjuvant Treatment in Stage IIIA NSCLC Patients With EGFR Mutationstreatment2unknown_status
NCT01926483
Phase II Trial of Regimen for Stage III (N2) NSCLC Using Induction Treatment Followed by ResectionNo drug interventionstreatment2unknown_status
NCT06268613
A Study to Compare the Pharmacokinetics, Efficacy, Safety, and Immunogenicity of Pembrolizumab (SB27, EU Sourced Keytruda, and US Sourced Keytruda) in Subjects With Stage II-IIIA NSCLC Following Complete Resection and Adjuvant Platinum-based Chemotherapytreatment1recruiting
NCT06117644
The Efficacy of Double-dose Furmonertinib in the Treatment of Patients With Slow Osimertinib-resistant NSCLCNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT04716946
Treating Early-stage Non-Small Cell Lung Cancer With Durvalumab and Radiation Therapytreatment2recruiting
NCT04326153
Neoadjuvant Immunotherapy Plus Chemotherapy for Potentially Resectable Stage IIIA/IIIB Non-Small Cell Lung Cancertreatment2active_not_recruiting
NCT01854684
Photodynamic Therapy During Surgery in Treating Patients With Non-small Cell Lung Cancer That Can Be Removed by Surgerytreatment1completed
NCT00369551
Bevacizumab, Paclitaxel, Carboplatin, and Radiation Therapy to the Chest in Treating Patients With Locally Advanced Non-Small Cell Lung Cancertreatment1terminated
NCT01345851
Image-Guided Hypofractionated Radiation Therapy With Stereotactic Body Radiation Therapy Boost and Combination Chemotherapy in Treating Patients With Stage II-III Non-Small Cell Lung Cancer That Cannot Be Removed By SurgerytreatmentNot Availableactive_not_recruiting
NCT01935947
Azacitidine and Entinostat Before Chemotherapy in Treating Patients With Advanced Non-small Cell Lung Cancertreatment2terminated
NCT01411098
Radiation Therapy, Cisplatin, and Etoposide in Treating Patients With Non-small Cell Lung Cancer That Cannot Be Removed by Surgerytreatment1terminated
NCT02621398
Pembrolizumab, Paclitaxel, Carboplatin, and Radiation Therapy in Treating Patients With Stage II-IIIB Non-Small Cell Lung Cancertreatment1active_not_recruiting
NCT01857271
Erlotinib Hydrochloride Before Surgery in Treating Patients With Stage III Non-Small Cell Lung Cancertreatment2terminated
NCT00020709
Combination Chemotherapy and Radiation Therapy With or Without Gefitinib in Treating Patients With Stage III Non-Small Cell Lung Cancer That Cannot Be Removed By Surgerytreatment3completed
NCT03048500
Nivolumab and Metformin Hydrochloride in Treating Patients With Stage III-IV Non-small Cell Lung Cancer That Cannot Be Removed by Surgerytreatment2unknown_status
NCT01806675
18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapydiagnostic1 / 2completed
NCT02897375
Palbociclib With Cisplatin or Carboplatin in Advanced Solid Tumorstreatment1completed
NCT02154399
EF5 in Measuring Tumor Hypoxia in Patients With Stage I-III Non-Small Cell Lung CancerNo drug interventionstreatment2completed
NCT01741636
Survivorship Care Planning in Patients With Colorectal or Non-Small Cell Lung CancerNo drug interventionssupportive_careNot Availablecompleted
NCT02655913
Safety and Efficacy of Vitamin C Infusion in Combination With Local mEHT to Treat Non Small Cell Lung Cancertreatment1 / 2completed
NCT03049618
Recombinant EphB4-HSA Fusion Protein and Pembrolizumab, MK-3475treatment2active_not_recruiting
NCT03916419
Magnetic Resonance-Guided Hypofractionated Adaptive Radiation Therapy With Concurrent Chemotherapy and Consolidation Durvalumab for Inoperable Stage IIB, IIIA, and Select IIIB and IIIC Non-small Cell Lung Cancertreatment2active_not_recruiting
NCT01781741
Stereotactic Body Radiation Therapy After Surgery in Treating Patients With Stage III-IV Non-small Cell Lung CancerNo drug interventionstreatment0completed
NCT01131234
Gamma-Secretase Inhibitor RO4929097 and Cediranib Maleate in Treating Patients With Advanced Solid Tumorstreatment1completed
NCT02819024
Dexamethasone Effects in Patients With Refractory Non-Small Cell Lung Cancer Using FLT Positron Emission TomographydiagnosticNot Availableactive_not_recruiting
NCT02495896
Recombinant EphB4-HSA Fusion Protein With Standard Chemotherapy Regimens in Treating Patients With Advanced or Metastatic Solid Tumorstreatment1terminated
NCT02947386
Nimotuzumab and Nivolumab in Treating Patients With Advanced Non-small Cell Lung Cancertreatment1completed
NCT00074022
GTI-2040 and Docetaxel in Treating Patients With Recurrent, Metastatic, or Unresectable Locally Advanced Non-Small Cell Lung Cancer, Prostate Cancer, or Other Solid Tumorstreatment1 / 2completed
NCT02243748
Palliative Care Intervention in Improving Symptom Control and Quality of Life in Patients With Stage II-IV Non-small Cell Lung Cancer and Their Family CaregiversNo drug interventionssupportive_careNot Availablecompleted
NCT00387465
Azacitidine and Entinostat in Treating Patients With Recurrent Advanced Non-Small Cell Lung Cancertreatment1 / 2completed
NCT00005065
Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With Stage IIIA Non-small Cell Lung Cancertreatment1completed
NCT01076231
Proton Beam Radiation Therapy and Chemotherapy in Treating Patients With Stage III Non-Small Cell Lung Cancer That Can Be Removed By Surgerytreatment1 / 2completed
NCT01886573
Azacitidine and Entinostat in Treating Patients With Newly Diagnosed Stage IA-IIIA Non-Small Lung Cancer Undergoing Surgerytreatment1terminated
NCT02879994
Pembrolizumab in Treating Patients With EGFR Mutant, Tyrosine Kinase Inhibitor Naive Advanced Non-Small Cell Lung Cancertreatment2completed
NCT02599194
18F-FSPG PET/CT for Cancer Patients on Therapydiagnostic2completed
NCT02059967
Phase I IGART Study Using Active Breathing Control and Simultaneous Boost for Patients With NSCLCtreatment1withdrawn
NCT02073968
PET-Adjusted Intensity Modulated Radiation Therapy and Combination Chemotherapy in Treating Patients With Stage II-IV Non-small Cell Lung Cancertreatment2completed
NCT01457469
Enhanced Quitline Intervention in Smoking Cessation for Patients With Non-Metastatic Lung Cancersupportive_care1completed
NCT00003869
Carboxyamidotriazole in Treating Patients With Stage III or Stage IV Non-small Cell Lung Cancertreatment3completed
NCT02607423
Fludeoxyglucose F-18 PET/CT in Predicting Response to Chemotherapy in Patients With Stage IIIA Non-small Cell Lung Cancer That Can Be Removed by Surgerydiagnostic2withdrawn
NCT01707823
Low-Dose Acetylsalicylic Acid in Treating Patients With Stage I-III Non-Small Cell Lung Cancerbasic_science0terminated
NCT04062708
CHIO3 Trial: CHemotherapy Combined With Immune Checkpoint Inhibitor for Operable Stage IIIA/B Non-Small Cell Lung Cancertreatment2active_not_recruiting
NCT00005838
Combination Chemotherapy Plus Radiation Therapy With or Without AE-941 in Treating Patients With Stage III Non-small Cell Lung Cancer That Cannot Be Removed By Surgerytreatment3completed
NCT03154190
Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With CancerNo drug interventionshealth_services_researchNot Availableunknown_status
NCT02823990
TG4010 and Nivolumab in Patients With Lung Cancertreatment2completed
NCT02566421
Genomic Sequencing in Determining Treatment in Patients With Metastatic Cancer or Cancer That Cannot Be Removed by SurgeryNo drug interventionstreatmentNot Availableterminated
NCT00020202
FR901228 in Treating Patients With Refractory or Progressive Small Cell Lung Cancer or Non-small Cell Lung Cancertreatment2completed
NCT01737502
Sirolimus and Auranofin in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer or Small Cell Lung Cancertreatment1 / 2completed
NCT05167487
Pathological Response After Neoadjuvant Treatment on NSCLCNot AvailableNot Availablerecruiting
NCT01282333
Veliparib, Cisplatin, and Gemcitabine Hydrochloride in Treating Patients With Advanced Biliary, Pancreatic, Urothelial, or Non-Small Cell Lung Cancertreatment1terminated
NCT01314677
Fludeoxyglucose F 18 PET/CT Scans in Predicting Therapy Response in Patients With Stage IIIA Non-Small Cell Lung Cancer Undergoing ChemoradiationNo drug interventionsdiagnosticNot Availablewithdrawn
NCT04776447
Atezolizumab Plus Induction Chemotherapy Plus CT-radiotherapy. (APOLO)treatment2active_not_recruiting
NCT02186847
Chemotherapy and Radiation Therapy With or Without Metformin Hydrochloride in Treating Patients With Stage III Non-small Cell Lung Cancertreatment2active_not_recruiting
NCT02987998
Neoadjuvant Chemoradiation Plus Pembrolizumab Followed By Consolidation Pembrolizumab in NSCLCtreatment1terminated
NCT01711697
An Alternative Radiation Fractionation Strategy for Locally Advanced Non-Small Cell Lung Cancer (NSCLC)treatment1unknown_status
NCT00662311
Vorinostat, Paclitaxel, and Radiation Therapy in Treating Patients Unable to Tolerate Cisplatin With Stage III Non-Small Lung Cancer That Cannot Be Removed By Surgerytreatment1 / 2terminated
NCT00963807
A Comparison of FLT to FDG PET/CT in the Early Assessment of Chemotherapy Response in Stage IB-IIIA Resectable NSCLCtreatment2completed
NCT02364609
Pembrolizumab and Afatinib in Patients With Non-small Cell Lung Cancer With Resistance to Erlotinibtreatment1completed
NCT00093756
Bortezomib, Paclitaxel, Carboplatin and Radiation Therapy for Non-Small Cell Lung Cancertreatment1 / 2completed
NCT03053856
Adjuvant Pembrolizumab in N2 Positive Non-small Cell Lung Cancer Patientstreatment2unknown_status
NCT02245100
Circulating Tumor DNA in Predicting Outcomes in Patients With Stage IV Head and Neck Cancer or Stage III-IV Non-small Cell Lung CancerNo drug interventionsNot AvailableNot Availablecompleted
NCT01342770
Pioglitazone Hydrochloride in Treating Patients With Stage IA-IIIA Non-small Cell Lung Cancertreatment2terminated
NCT01935336
Study of Ponatinib in Patients With Lung Cancer Preselected Using Different Candidate Predictive Biomarkerstreatment2completed
NCT01726296
Adherence to Survivorship Care Guidelines in Health Care Providers for Non-Small Cell Lung Cancer and Colorectal Cancer Survivor CareNo drug interventionshealth_services_researchNot Availablecompleted
NCT02567396
Talazoparib in Treating Patients With Advanced or Metastatic Solid Tumors That Cannot Be Removed by Surgery and Liver or Kidney Dysfunctiontreatment1withdrawn
NCT02728596
S1415CD, Trial Assessing CSF Prescribing Effectiveness and Risk (TrACER)No drug interventionshealth_services_researchNot Availablecompleted
NCT01155258
Temsirolimus and Vinorelbine Ditartrate in Treating Patients With Unresectable or Metastatic Solid Tumorstreatment1completed
NCT00042835
Erlotinib and Radiation Therapy Plus Combination Chemotherapy in Treating Patients With Inoperable Stage III Non-Small Cell Lung Cancertreatment1terminated
NCT02134886
Erlotinib Hydrochloride in Treating Non-Small Cell Lung Cancer That is Metastatic or Cannot be Removed by Surgery in Patients With HIV Infectiontreatment1terminated
NCT02262325
Hypofractionated Boost Before Chemoradiation for Patients With Stage II-III Non-small Cell Lung Cancer Unsuitable for Surgerytreatment2active_not_recruiting
NCT02017925
Pulmonary Rehabilitation in Improving Lung Function in Patients With Locally Advanced Non-Small Cell Lung Cancer Undergoing ChemoradiationNo drug interventionssupportive_careNot Availablewithdrawn
NCT03366766
Nivolumab, Cisplatin, and Pemetrexed Disodium or Gemcitabine Hydrochloride in Treating Patients With Stage I-IIIA Non-small Cell Lung Cancer That Can Be Removed by Surgerytreatment2completed
NCT01595074
Biomarkers in Predicting Treatment Response in Samples From Patients With Early-Stage Non-Small Cell Lung Cancer Previously Treated With Adjuvant ChemotherapyNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT00004074
Interleukin-12 and Trastuzumab in Treating Patients With Cancer That Has High Levels of HER2/Neutreatment1completed
NCT02276560
Cisplatin and Nab-paclitaxel for (N2) Defined NSCLCtreatment2terminated
NCT00040794
Combination Chemotherapy, Radiation Therapy, and Gefitinib in Treating Patients With Stage III Non-Small Cell Lung Cancertreatment2completed
NCT00087191
EF5 and Motexafin Lutetium in Detecting Tumor Cells in Patients With Abdominal or Non-Small Cell Lung CancerdiagnosticNot Availableterminated
NCT02059889
Diffusion-weighted MRI for Individualized Radiation Therapy Planning of Lung CancerNo drug interventionsdiagnosticNot Availablewithdrawn
NCT05894889
Pembrolizumab and Chemotherapy Neoadjuvant/Adjuvant of NSCLCtreatment2recruiting
NCT01971489
Buparlisib, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Advanced Solid Tumorstreatment1withdrawn
NCT00778167
Erlotinib Hydrochloride With or Without Cixutumumab in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancertreatment1 / 2completed
NCT01958372
Radiation Therapy, Chemotherapy, and Soy Isoflavones in Treating Patients With Stage IIIA-IIIB Non-Small Cell Lung Cancertreatment1completed
NCT01383668
Sirolimus and Gold Sodium Thiomalate in Treating Patients With Advanced Squamous Non-Small Cell Lung Cancertreatment1withdrawn
NCT00087269
Erlotinib in Treating Patients With Stage I-IIIA Non-Small Cell Lung Cancer Undergoing Surgical Resectiontreatment2terminated
NCT03433469
Osimertinib in Treating Participants With Stage I-IIIA EGFR-mutant Non-small Cell Lung Cancer Before Surgerytreatment2active_not_recruiting
NCT01999881
Impacts of Exercise on Prognostic Biomarkers in Lung Cancer PatientsNo drug interventionssupportive_careNot Availablecompleted
NCT00738881
Pemetrexed Disodium or Erlotinib Hydrochloride as Second-Line Therapy in Treating Patients With Advanced Non-small Cell Lung Cancertreatment3terminated
NCT00063895
Erlotinib in Treating Patients With Advanced Non-Small Cell Lung Cancer, Ovarian Cancer, or Squamous Cell Carcinoma of the Head and Necktreatment1 / 2completed
NCT01413750
Carboplatin and Paclitaxel With or Without Vorinostat in Treating Patients With Advanced Non-Small Cell Lung Cancertreatment1 / 2terminated
NCT00049543
Gefitinib in Treating Patients With Stage IB, II, or IIIA Non-small Cell Lung Cancer That Was Completely Removed by Surgerytreatment3completed
NCT00078390
Study of S-3304 in Patients With Locally Advanced Non-Small Cell Lung Cancertreatment1 / 2completed