Sjögren's Syndrome (SS) (DBCOND0163993)

Identifiers

Synonyms
Sjogren Disease / Sjogren's Syndrome (SS) / Sjogrens Syndrome / Sjogrens Disease / Sjögren's Syndrome / Sjögren Syndrome / Sjogren's Disease / Sjogren's Syndrome / Sjogren Syndrome / Gougerot-Mulock-Houwer syndrome / Sjogren's / Syndrome Sjogren's / Sjoegren's syndrome / Sjögren's syndrome (disorder) / Sicca Syndrome / Syndrome sicca

Associated Data

Indicated Drugs and Targets
DrugDescriptionTargets
Cevimeline
A muscarinic agonist with parasympathomimetic activities that is used for the symptomatic treatment of dry mouth in patients with Sjögren's Syndrome.
Hydroxychloroquine
An antimalarial medication used to treat uncomplicated cases of malaria and for chemoprophylaxis in specific regions. Also a disease modifying anti-rheumatic drug (DMARD) indicated for treatment of rheumatoid arthritis and lupus erythematosus.
Pilocarpine
A muscarinic agonist used to treat dry mouth and various ophthalmic conditions, such as presbyopia, increased intraocular pressure, and angle-closure glaucoma.
Prednisolone
A glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers.
Prednisone
A corticosteroid used to treat inflammation or immune-mediated reactions and to treat endocrine or neoplastic diseases.
Sodium molybdate
Not Annotated
No drug targets
Clinical Trials
IdentifierTitleDrug(s)PurposePhaseStatus
NCT06411639
Pharmacokinetics Study of Ianalumab in Chinese Participants With Autoimmune Diseasestreatment1not_yet_recruiting
NCT06245408
A Safety and Efficacy Study of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-Severe Symptom Statetreatment3recruiting
NCT05217472
An Efficacy and Safety Study of Injectable Ravagalimab to Assess Change in EULAR Sjogren's Syndrome Disease Activity Index (ESSDAI) in Adult Participants With Moderately to Severely Active Primary Sjogren's Syndrome (pSS)treatment2withdrawn
NCT05985915
A Randomized, Double-blind 2-arm NEPTUNUS Extension Study to Assess the Long-term Safety and Efficacy of Ianalumab in Patients With Sjogrens Syndrome.treatment3recruiting
NCT01470638
A Study of Flt3-Ligand Levels in Sjögrens SyndromeNo drug interventionsNot AvailableNot Availablecompleted
NCT02915159
A Study to Assess the Efficacy and Safety of Abatacept in Adults With Active Primary Sjögrens Syndrometreatment3completed
NCT06583395
Quest to Analyze One Thousand Humans MeditatingNo drug interventionsNot AvailableNot Availableenrolling_by_invitation
NCT03060005
Is Sjögren's Syndrome Associated With Meibomian Gland Dysfunction ?treatmentNot Availableunknown_status
NCT02849093
Optical Coherence Tomography of Ocular Structures in Epiphora and Dry Eye Syndrome.No drug interventionsNot AvailableNot Availableunknown_status
NCT03937271
Objective Measurement Methods for Autoimmune Disease and Dry Eye SyndromeNo drug interventionsNot AvailableNot Availablewithdrawn
NCT04747288
Objective Measurement With TCM Pattern for AIDDESNo drug interventionsNot AvailableNot Availablerecruiting
NCT02843659
Proof of Concept Study to Evaluate the Efficacy and Safety of BMS-931699 (Lulizumab) or BMS-986142 in Primary Sjögren's Syndrometreatment2terminated
NCT06544642
A Study to Evaluate the Effects of ASP5502 in Healthy Adults and Adults With Primary Sjögren's SyndromeNo drug interventionsbasic_science1recruiting
NCT04111341
A Clinical Trial to Evaluate the Safety and Efficacy of Traditional Chinese Medicine in Sjögren's Syndrome.No drug interventionsbasic_science2completed
NCT02614716
A Study of LY3090106 in Participants With Sjögren's Syndrome (SS)basic_science1completed
NCT00873496
Effects of Hydroxychloroquine on Oral Complaints of Sjögren PatientsNot AvailableNot Availablecompleted
NCT02855658
Modulation of Immunity-related Gene Expression Under the Chinese Herbal Formula SS-1 Treatment for Sjögren's SyndromeNo drug interventionstreatment2unknown_status
NCT01160666
Efficacy and Safety of Belimumab in Subjects With Primary Sjögren's Syndrometreatment2completed
NCT01008982
Efficacy and Safety of Belimumab in Primary Sjögren's Syndrometreatment2completed
NCT03935373
DNA Exome Sequencing TCM for Sjögren's SyndromeNo drug interventionsNot AvailableNot Availableunknown_status
NCT01174329
Treatment of Salivary Gland Hypofunction With Neuro- ElectrostimulationNo drug interventionstreatment2 / 3unknown_status
NCT03983408
Impact of Korean Red Ginseng on Fatigue in Patients With Rheumatic DiseaseNo drug interventionssupportive_careNot Availableunknown_status
NCT05680064
The Effect of Chewing Gum, Exercises of the Tongue, Lip, Jaw on Salivation, Xerostomia, Dysphagia in Sjögren's SyndromeNo drug interventionssupportive_careNot Availablecompleted
NCT04129164
A Study to Evaluate the Efficacy and Safety of VIB4920 in Participants With Sjögren's Syndrometreatment2completed
NCT04798911
SS-INQ Information Needs Questionnaire in Sjögren's SyndromeNo drug interventionsNot AvailableNot Availablecompleted
NCT02833311
e-Mobile Tablet for People With Chronic ConditionsNo drug interventionssupportive_careNot Availablecompleted
NCT02422407
A Longitudinal, Observational Biomarker Study in Participants With Primary Sjogren's SyndromeNo drug interventionsNot AvailableNot Availablecompleted
NCT01316770
Dexamethasone Irrigation of the Parotid Glands in Primary Sjögren's Syndrome Subjectstreatment2terminated
NCT03434106
Sjögren's Syndrome Is Associated With Meibomian Gland DysfunctiontreatmentNot Availableunknown_status
NCT02112019
Endoscopic Treatment of Salivary Glands Affected by Sjögren's Syndromesupportive_careNot Availableunknown_status
NCT05946941
A Study to Evaluate the Efficacy and Safety of Deucravacitinib in Adults With Active Sjögren's Syndrometreatment3recruiting
NCT04572841
Safety, Tolerability, Pharmacokinetics, and Therapeutic Efficacy of SAR441344 in Primary Sjögren's Syndrome (pSjS)treatment2completed
NCT05633524
HRR as a Novel Biomarker in Sjögren's SyndromeNo drug interventionsNot AvailableNot Availablecompleted
NCT05605665
Low-dose Interleukin-2 and Rapamycin on sjögren's Syndrometreatment1 / 2completed
NCT01807689
Salivary Biomarkers for Sjögren's Syndrome DetectionNo drug interventionsNot AvailableNot Availablecompleted
NCT01151644
Safety and Efficacy of Anti-Pandemic H1N1 Vaccination in Rheumatic DiseasesNo drug interventionsprevention4unknown_status
NCT00100204
Salivary Proteins in Disease and HealthNo drug interventionsNot AvailableNot Availablecompleted
NCT02110446
Evaluation of the Efficacy and the Mechanism of Chinese Herbal Formula SS-1 for Sjögren's SyndromeNo drug interventionstreatment2unknown_status
NCT02067910
Efficacy and Safety of Abatacept in Patients With Primary Sjögren's Syndrometreatment3completed
NCT03941184
Spontaneous Coronary Artery Dissection (SCAD) and AutoimmunityNo drug interventionsNot AvailableNot Availablecompleted
NCT06411132
Study to Evaluate Corneal Neurosensory Abnormalities in Patients With Sjögren's Dry EyeNo drug interventionsNot AvailableNot Availablerecruiting
NCT04819269
Tivanisiran for Dry Eye in Subjects With Sjögren's SyndromeNo drug interventionstreatment3completed
NCT02752269
Early Detection of Pulmonary- and Pulmonary Vascular Disease in Sjögren SyndromeNo drug interventionsNot AvailableNot Availablecompleted
NCT03608761
Comparison Between Rebamipide 2% Versus Autologous Serumtreatment4completed
NCT04848870
Dental and Periodontal Status of Patients With Sjögren's Syndrome.No drug interventionsNot AvailableNot Availablerecruiting
NCT03762824
Combined Pneumococcal Conjugate and Polysaccharide Vaccination in Inflammatory Rheumatic Diseaseprevention4completed
NCT03905525
Study of Safety and Efficacy of Multiple Doses of CFZ533 in Two Distinct Populations of Patients With Sjogren's Syndrometreatment2completed
NCT02011776
A Randomized, Parallel-Group Comparison Study of Topical Corticosteroids in Dry Eye Patients With Sjögren SyndromeNo drug interventionsNot AvailableNot Availablecompleted
NCT04035668
A Phase 2 Study to Evaluate the Safety and Efficacy of LOU064 in Patients With Moderate to Severe Sjögren's Syndromeother2terminated
NCT04793646
N-acetylcysteine for Primary Sjögren's SyndrometreatmentNot Availableactive_not_recruiting
NCT02049112
A New Oral salIvary equivAlent Compared to Two moisturizinG Mouth sprAys in Patients With xeRostomiA: NIAGARA StudyNo drug interventionstreatment4completed
NCT05079581
Pelvic Floor Exercises in Patients With Sjögren'sNo drug interventionstreatmentNot Availablecompleted
NCT01234623
Cord Blood Serum in the Treatment of Ocular Surface DiseasesNo drug interventionsNot AvailableNot Availablecompleted
NCT02148497
Multi-Colored Placido Disk ViabilityNo drug interventionsdiagnosticNot Availablecompleted
NCT02322528
Evaluation of Ocular Surface Inflammatory Mediators Effected by LotemaxdiagnosticNot Availablecompleted
NCT06392711
Dose-Escalation Trial of Mesenchymal Stromal Cells in Patients with Medical Xerostomiatreatment1not_yet_recruiting
NCT02358213
Evaluation of the Reproducibility Inter-observer of the Ultrasound Anomalies of the Salivary Glands in Sjogren's DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT00740948
Tolerance and Efficacy of Rituximab in Sjogren's Diseasetreatment2 / 3completed
NCT00809003
Assessment of Inflammatory and Functional Changes in the Ocular Surface Associated With Dry Eye DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT03064984
Blood Based Eyedrops From Different Sources in the Treatment of Severe KeratopathyNo drug interventionstreatmentNot Availableunknown_status
NCT02327884
Characterization of Diseases With Salivary Gland InvolvementNo drug interventionsNot AvailableNot Availablerecruiting
NCT05115487
Evaluation of Hand Functions in Newly Diagnosed Primary Sjögren's SyndromeNo drug interventionsNot AvailableNot Availableunknown_status
NCT06420154
The Safety and Efficacy of Anti-CD19 CAR-T Cells in Patients With Relapsed/Refractory Autoimmune DiseasesNo drug interventionstreatment0not_yet_recruiting
NCT00001953
The Functioning of Immune and Hormonal Systems in Patients With Sjogren's Syndrome and in Healthy VolunteersNo drug interventionsNot AvailableNot Availablecompleted
NCT04802577
Fatigue in Primary Sjögren's SyndromeNo drug interventionsNot AvailableNot Availablecompleted
NCT04649177
Pilot Study to Investigate the Feasibility, Reliability and Efficacy of Utilizing OCT to Automate PROSE FittingNo drug interventionstreatmentNot Availablecompleted
NCT00001598
DHEA Treatment for Sjogren's Syndrometreatment2completed
NCT06313905
EVADRY® in the Treatment of Xerostomia in Sjögren's SyndromeNo drug interventionstreatmentNot Availablenot_yet_recruiting
NCT05016297
Efficacy and Safety of Baricitinib in Sjogren's Syndrometreatment2active_not_recruiting
NCT04978883
Interstitial Lung Diseases in Primary Sjogren's SyndromeNo drug interventionsNot AvailableNot Availablecompleted
NCT04530461
Serologic Profile of SARS CoV2 in COVID-19 Patients With Systemic DiseasesNo drug interventionsNot AvailableNot Availableunknown_status
NCT01601028
Hydroxychloroquine Treatment of Dry Eyes in Patients With Primary Sjögren's Syndrometreatment3completed
NCT04119128
tDCS for Fatigue in Sjogren's SyndromeNo drug interventionstreatmentNot Availablecompleted
NCT03157011
Evaluation of the Prevalence of Functional Digestive Disorders During Primary Sjögren Gougerot SyndromeNo drug interventionsbasic_scienceNot Availablecompleted
NCT06401811
Reliability, Validity, and Responsiveness of the Turkish Version of Eating Assessment Tool-10 for Patients With Primer Sjögren's SyndromeNo drug interventionsNot AvailableNot Availablerecruiting
NCT00637793
Study of NGX267 Oral Capsules in Patients With Xerostomia Associated With Sjorgren's Syndrometreatment2completed
NCT04895878
Patients With Co-occurrence of ANCA Vasculitis and Sjögren SyndromeNo drug interventionsNot AvailableNot Availablecompleted
NCT06428188
Sequential CAR-T Cells Targeting BCMA/CD19 in Patients With Relapsed/ Refractory Autoimmune DiseasesNo drug interventionstreatment1 / 2recruiting
NCT03430388
Yellow Fever Vaccine in Patients With Rheumatic DiseasespreventionNot Availablecompleted
NCT02203188
Effect of Debridement-scaling on the Relief of Dry Eye Signs and Symptoms in Sjogren's SyndromeNo drug interventionstreatmentNot Availablecompleted
NCT05927688
Assessment of Physician Consideration of ePRO's, From Patients With Gout, Rheumatoid Arthritis, Sjogren's Syndrome or Systemic Lupus, on the Frequency of Therapeutic AdjustmentsNo drug interventionsNot AvailableNot Availablerecruiting
NCT03938207
Dry Eye Syndrome, Healthy Control, Sjögren's Syndrome and Other Inflammation Disease in Taiwan BiobankNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT04252209
the Effect of Mixture of Natural Products As Salivary Substitutes in Treatment Of XerostomiaNo drug interventionstreatment3completed
NCT03937856
Smartphone Mindfulness Meditation for Patients With Rheumatic DiseasesNo drug interventionstreatmentNot Availableterminated
NCT04916756
A Prospective Pilot Study to Explore Efficacy and Safety of Baricitinib in Active Primary Sjogren's Syndrome Patientstreatment1 / 2completed
NCT04839315
COVID-19 Vaccination in Rheumatic Disease PatientsNo drug interventionshealth_services_research0terminated
NCT04397237
Prevalence and Seroconversion of COVID-19 in Autoimmune Diseases in EuropeNo drug interventionsNot AvailableNot Availableunknown_status
NCT01393132
Comparative Study of Thymosin Beta 4 Eye Drops vs. Vehicle in the Treatment of Severe Dry Eyetreatment2completed
NCT06437652
An AI Algorithm for Lymphocyte Focus Score of Minor Salivary Gland Biopsy Samples for Diagnosing Sjogren's SyndromeNo drug interventionsNot AvailableNot Availablerecruiting
NCT00001852
Natural History of Salivary Gland Dysfunction and Sjogren's SyndromeNo drug interventionsNot AvailableNot Availablecompleted
NCT04345159
Association Between Long-term Hydroxychloroquine Treatment and Outcome of a History of Symptoms Suggestive of COVID-19 Infection During the Epidemic Period in France in Patients With Autoimmune DiseaseNo drug interventionsNot AvailableNot Availablecompleted
NCT06454370
Histopathological Analysis Versus Full-field Optical Coherence Tomography of Minor Salivary Gland Biopsy in Suspect Sjogren SyndromeNo drug interventionsNot AvailableNot Availablerecruiting
NCT03100942
Study to Assess Safety and Efficacy of Filgotinib, Lanraplenib and Tirabrutinib in Adults With Active Sjogren's Syndrometreatment2completed
NCT06410742
Evaluation of Biopsychosocial Features, Pain, Fatigue, Quality of Life, Swallowing, and Disease-Specific Symptoms in Patients With Primer Sjogren's SyndromeNo drug interventionsNot AvailableNot Availablerecruiting
NCT04546542
Hydroxychloroquine Blood Levels in Primary Sjögren Syndrome PatientsNo drug interventionsNot AvailableNot Availablecompleted
NCT01642706
Regulatory B Cells in Inflammatory Rheumatisms and Biomarkers of Response to Biologic TreatmentsNo drug interventionsNot AvailableNot Availableunknown_status
NCT05782049
Ultrasound Characteristics of the Salivary Glands in Patients With Rheumatoid ArthritisNo drug interventionsotherNot Availablerecruiting
NCT06013436
AST Combined With 0.05% Cyclosporin Eye Drop Improve Corneal Nerve Density in Patients With SS Dry EyeNot AvailableNot Availablecompleted
NCT03248518
Lessening the Impact of Fatigue in Inflammatory Rheumatic DiseasesNo drug interventionstreatmentNot Availablecompleted
NCT00025818
Six Month Clinical Research Study for Patients With Moderate or Severe Dry Eye Syndrometreatment3completed
NCT04143841
Viveye Ocular Magnetic Neurostimulation System (OMNS) for the Management of Severe Dry Eye DiseaseNo drug interventionstreatmentNot Availableterminated
NCT05656196
VGH-DESJS-1 in Ocular and Oral Dryness Symptoms of Dry Eye Syndrome and Sjögren's SyndromeNo drug interventionsotherNot Availablecompleted
NCT04653935
Pilot Feasibility Study of a Sjögren's Syndrome Self-management AppNo drug interventionstreatmentNot Availableunknown_status
NCT00233363
Exploratory Study for Dry Mouth in Patients With Sjögren's Syndrometreatment2completed
NCT02370225
Aerobic Exercise in Primary Sjögren's SyndromeNo drug interventionstreatmentNot Availablecompleted
NCT03204448
Clinical Performance of BioCLIA Ro60No drug interventionsNot AvailableNot Availablewithdrawn
NCT06339957
Rheumatology Diet StudyNo drug interventionsNot AvailableNot Availablerecruiting
NCT06364657
Differences in Corneal Structure and Function in Patients With Sjogrens vs. Non-Sjogrens Dry EyeNo drug interventionsNot AvailableNot Availablerecruiting
NCT03757065
Cell Surface Marker Expression in Autoimmune DiseasesNo drug interventionsNot AvailableNot Availablecompleted
NCT06312020
A Phase 2 Study to Investigate Efficacy and Safety of HZN-1116 in Participants With Sjogren's SyndromeNo drug interventionstreatment2recruiting
NCT06475027
Exosome-miRNA and Transcriptome Profiling of Dry Eye Syndrome and Sjogren's SyndromeNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT03436576
Efficacy of Two Concentrations of Autologous Serum for the Treatment of Severe Dry Eyetreatment3unknown_status
NCT04931160
B-dependant Rare AutoImmune diseaSES - Cohort of Patients With Suspected Diagnosis of Primitive Sjögren SyndromeNo drug interventionsotherNot Availablerecruiting
NCT00513591
Duke Autoimmunity in Pregnancy RegistryNo drug interventionsNot AvailableNot Availablecompleted
NCT00101829
Anti-CD20 Antibody Therapy for Sjogren's Syndrometreatment1completed
NCT01369589
An Evaluation of the Impact of a Single Dose of P-552 on Oral Mucosal Wetnesstreatment1 / 2completed
NCT03023592
Study of Iguratimod in Sjögren's Syndrometreatment1 / 2unknown_status
NCT05312944
Polymyalgia Rheumatica Associated to Primary Sjogren SyndromeNo drug interventionsNot AvailableNot Availableunknown_status
NCT04462601
Descriptive Study of Variations in Serum Translocation Markers of the Intestinal Microbiota in Patients With Gougerot-Sjögren Syndrome According to Disease ActivityNo drug interventionsNot AvailableNot Availablerecruiting
NCT01716312
Omalizumab for Lupustreatment1completed
NCT04968912
A Study of Nipocalimab in Adults With Primary Sjogren's Syndrome (pSS)other2completed
NCT05056012
Penn SICCA Follow-up StudyNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT06373081
Anti-CD19-CD3E-CAR-T Cells in Relapsed/Refractory Autoimmune DiseaseNo drug interventionstreatmentNot Availablerecruiting
NCT05644795
Wheat-free Diet in the Treatment of Sjogren's SyndromeNo drug interventionstreatmentNot Availablerecruiting
NCT03711214
Immune Profile of Saliva and Serum of Patients With Primary Sjögren´s SyndromeNo drug interventionstreatmentNot Availableactive_not_recruiting
NCT05015114
Prevalence and Factors of Sarcopenia and in Patients With Primary Sjogren's SyndromeNo drug interventionsNot AvailableNot Availablecompleted
NCT04909255
Beta-3 Agonist and Anti-muscarinic Agent for Sjogren's Syndrome With Overactive Bladdertreatment4unknown_status
NCT00363350
Rituximab Treatment in Sjogren's Syndrometreatment1 / 2completed
NCT03411850
Sjogrens Syndrome Measured by Ultrasoundother2unknown_status
NCT03540823
Evaluation of Influenza A/H3N2 Vaccine in Patients With Rheumatologic DiseasesNo drug interventionsprevention4completed
NCT04835623
CEQUA for Sjogren's Syndrome Dry Eyetreatment4completed
NCT03276923
Maternal Autoimmune Disease Research Alliance (MADRA) RegistryNo drug interventionsNot AvailableNot Availablerecruiting
NCT02661243
Implantology and Sjögren's SyndromeNo drug interventionstreatmentNot Availablecompleted
NCT03953703
Levocarnitine for Dry Eye in Sjogren's Syndrometreatment2recruiting
NCT04239521
The Epidemiology, Management, and the Associated Burden of Related Conditions in Alopecia AreataNo drug interventionsNot AvailableNot Availablecompleted
NCT04056221
Effects of Acupuncture on Sjögren's SyndromeNo drug interventionstreatmentNot Availablecompleted
NCT06056921
Safety and Efficacy of CD19 Targeted CAR-T Therapy for Refractory Autoimmune DiseaseNo drug interventionstreatment1recruiting
NCT06410833
Belimumab After Rituximab in Resistant Primary Juvenile SStreatment4recruiting
NCT06406933
Salivary Conductivity Screening for Primary Sjögren's SyndromeNot AvailableNot Availablerecruiting
NCT00001954
Etanercept Therapy for Sjogren's Syndrometreatment2completed
NCT05383677
Anifrolumab Treatment for 24 Weeks in Patients With Primary Sjögren's Syndrometreatment2recruiting
NCT02691377
Acupuncture for Primary Sjögren SyndromeNo drug interventionstreatment2unknown_status
NCT01357447
Pulmozyme for Sjogren's Associated Coughsupportive_care1withdrawn
NCT02123147
Examining the Immunological Process of Autoimmune PatientsNo drug interventionsNot AvailableNot Availablewithdrawn
NCT04843345
Sjogren's Lung StudyNo drug interventionsNot AvailableNot Availablesuspended
NCT06417398
Preliminary Clinical Study of UTAA09 Injection in the Treatment of Relapsed/Refractory Autoimmune DiseasesNo drug interventionstreatment0not_yet_recruiting
NCT03012698
Pilot Study for Testing Safety of Repetitive Magnetic Stimulation for Treatment of Dry EyeNo drug interventionstreatmentNot Availablecompleted
NCT05859997
Universal CAR-T Cells (BRL-301) in Relapse or Refractory Autoimmune DiseasesNo drug interventionstreatmentNot Availablerecruiting
NCT03611283
Topical Management of Xerostomia With Dry Mouth ProductsNo drug interventionstreatmentNot Availablecompleted
NCT00750828
Gingival Wetness and Gingival Crevicular Fluid Volume in Patients With Dry MouthNo drug interventionsNot AvailableNot Availablecompleted
NCT01079871
Evaluation of FID 114657 in Sjogren's Syndrome SubjectsNo drug interventionstreatmentNot Availablecompleted
NCT06548607
Clinical Study on Targeted CD19 CAR-T Therapy for Autoimmune DiseasesNo drug interventionstreatment0recruiting
NCT02701985
A Study to Assess the Efficacy of RO5459072 in Participants With Primary Sjogren's Syndrometreatment2completed
NCT03719885
TrueTear in Sjogren's Disease PatientsNo drug interventionstreatmentNot Availablecompleted
NCT00953485
Allogeneic Mesenchymal Stem Cells Transplantation for Primary Sjögren's Syndrome (pSS)No drug interventionstreatment1 / 2unknown_status
NCT03578900
Quality of Life and Sjögren Syndrometreatment4completed
NCT06536075
Functional Analysis of Salivary Glands and Correlation With Sialoscintigraphy in Sjogren's SyndromeNo drug interventionsdiagnosticNot Availablerecruiting
NCT04749875
Study of Leukocyte Populations in Patients With Chronic InflammatoryNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT03327870
Oral Health Needs Assessment of Sjogren s Syndrome and Salivary Gland Dysfunction Cohorts and Healthy Volunteers Evaluating Oral Health Disparities as Determinants of Oral Health in a High-Risk PopulationNo drug interventionsNot AvailableNot Availablecompleted
NCT00001599
Pilot Study of Thalidomide to Treat Sjogren's Syndrometreatment2completed
NCT05005806
Fish Oil (Omega 3 ) in Sjogren's SyndromeNo drug interventionstreatment2 / 3completed
NCT02691949
Efficacy and Safety of Mycophenolate Mofetil in subjectswithSjogren's Syndrometreatment2unknown_status
NCT05689749
Superb Microvascular Imaging Ultrasonography of Lacrimal Gland in Patients With Sjögren SyndromeNo drug interventionsNot AvailableNot Availablecompleted
NCT06297213
R-2487 in Patients With Sjogren's Syndrome (SS)treatment1not_yet_recruiting
NCT03841318
Involvement of Immune Cells Derived From the Intestine in Sjogren's SyndromeNo drug interventionsotherNot Availablerecruiting
NCT05879419
Recombinant Herpes Zoster Vaccine in Patients With Autoimmune Rheumatic Diseasesprevention4recruiting
NCT03817424
A Study to Evaluate VIB7734 in Participants With Systemic Lupus Erythematosus (SLE), Cutaneous Lupus Erythematosus (CLE), Sjogren's Syndrome, Systemic Sclerosis, Polymyositis, and Dermatomyositistreatment1completed
NCT06104124
A Study to Evaluate the Efficacy and Safety of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-severe Systemic Disease Activitytreatment3recruiting
NCT00391924
Dehydroepiandrosterone Administration in Women With Systemic Lupus Erythematosus or Primary Sjögren's Syndrometreatment2completed
NCT06549296
Clinical Study on Targeted CD19CAR-T Therapy for Autoimmune DiseasesNo drug interventionstreatment0not_yet_recruiting
NCT00001196
Evaluation of Salivary Gland DysfunctionNo drug interventionsNot AvailableNot Availableterminated
NCT04493658
Differential Diagnosis of Sjögren's Versus Non-Sjögren's Dry EyeNo drug interventionsNot AvailableNot Availablecompleted
NCT00631358
Assessment of Inflammatory Biomarkers Expressed in a Sjogren's Population: Effect of a Topical Steroid Interventiontreatment4completed
NCT06338735
Ultra-High Frequency Ultrasonography in Sjögren's SyndromeNo drug interventionsdiagnosticNot Availablerecruiting
NCT05715463
Rheumatology-based Adaptive Intervention for Social Determinants and Health EquityNo drug interventionsotherNot Availablerecruiting
NCT04402086
Rheumatology Patient Registry and BiorepositoryNo drug interventionsNot AvailableNot Availablerecruiting
NCT03926286
Fecal Microbial Transplant (FMT) for Sjogrens SyndromeNo drug interventionstreatment1completed
NCT03247686
A Study of RSLV-132 in Subjects With Primary Sjogren's SyndromeNo drug interventionstreatment2completed
NCT05700422
Nasal Spray Study in Sjogren's Dry Eye Diseasetreatment4completed
NCT04313725
Evaluation of Tangible Boost for Patients With Stevens Johnson Syndrome, Sjogren's Syndrome, and Graft Vs Host DiseaseNo drug interventionstreatmentNot Availableunknown_status
NCT00344448
Pilot Study of Raptiva to Treat Sjogren's Syndrometreatment2terminated
NCT00565526
Evaluation of the Role of the Autonomic Nervous System in Sj(SqrRoot)(Delta)Gren s SyndromeNo drug interventionsNot AvailableNot Availablecompleted
NCT00543166
Sex Steroids in Sjögren's Syndrome: Effect of Substitution Treatment on Fatiguetreatment4unknown_status
NCT03501420
Adelphi Primary Sjogren's Syndrome (pSS) Disease Specific Programme (DSP)No drug interventionsNot AvailableNot Availablecompleted
NCT03203382
Corneal Nerve Structure in Sjogren'sNo drug interventionsNot AvailableNot Availablecompleted
NCT05085431
A Study of CD19/BCMA Chimeric Antigen Receptor T Cells Therapy for Patients With Refractory Sjogren's SyndromeNo drug interventionstreatment0recruiting
NCT00001731
Treatment of Dry Eye Syndrome With Cyclosporin A Eye Dropstreatment2completed
NCT00074373
The Research Registry for Neonatal LupusNo drug interventionsNot AvailableNot Availablecompleted
NCT04496960
Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren's Syndrometreatment1 / 2recruiting
NCT00023491
Potential of Transplanted Stem Cells to Mature Into Salivary Gland and Cheek CellsNo drug interventionsNot AvailableNot Availablecompleted
NCT04541589
Study of Safety and Tolerability of CFZ533 in Patients With Sjögren's Syndrometreatment2completed
NCT01425892
The Pathogenesis and Natural History of Sjogren's DiseaseNo drug interventionsNot AvailableNot Availablerecruiting
NCT01931644
At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic ConditionsNo drug interventionsNot AvailableNot Availablecompleted
NCT06530940
Diagnostic Interest of the Buccal Schirmer Test in Xerostomia During Sjögren's Syndrome: XERODIAGNo drug interventionsNot AvailableNot Availablenot_yet_recruiting
NCT05961267
Study of Gynecological Follow-up of Patients With Autoimmune Disease or Inflammatory RheumatismNo drug interventionsNot AvailableNot Availablerecruiting
NCT05904301
Armenian NAtionwide REGistry of Systemic Autoimmune and Autoinflammatory DiseasesNo drug interventionsNot AvailableNot Availablerecruiting
NCT02031172
Effects of Sustained Reading on the Ocular SurfaceNo drug interventionsNot AvailableNot Availableterminated
NCT06324968
Ro60 Expression in Macrophages in Sjogren's DiseaseNo drug interventionsdiagnosticNot Availablerecruiting
NCT02920346
Prospective Maternal Surveillance of SSA (Sjögren Syndrome A) Positive Pregnancies Using a Hand-held Fetal Heart Rate MonitorNo drug interventionsNot AvailableNot Availablecompleted
NCT05958446
Fetal-Hope Study: Home Monitoring of Fetal Heart Rate in SSA+ Pregnant WomenNo drug interventionsNot AvailableNot Availablerecruiting
NCT06379646
An Clinical Study of YTS109 Cell Injection in Subjects With Recurrent/Refractory Autoimmune DiseaseNo drug interventionstreatmentNot Availablerecruiting
NCT03473912
Meir Medical Center Rheumatologic BiobankNo drug interventionsNot AvailableNot Availablerecruiting
NCT04909112
Olfactory and Taste Disturbances in Sjogren's SyndromeNo drug interventionsbasic_scienceNot Availableunknown_status
NCT06350110
Fourth-gen CAR T Cells Targeting BCMA/CD19 for Refractory Systemic Lupus Erythematosus (SLE)No drug interventionstreatment1 / 2not_yet_recruiting
NCT06363955
Assessing the Efficacy of a Carbamide Peroxide Mouthwash for Oral Wound Healing, Oral Hygiene and Xerostomia ReliefNo drug interventionstreatmentNot Availablecompleted
NCT02370550
Cyclosporine A in the TReatment of Interstitial Pneumonitis Associated With Sjogren's Syndrometreatment4unknown_status
NCT02631538
Safety and Efficacy Study of Subcutaneous Belimumab and Intravenous Rituximab Co-administration in Subjects With Primary Sjogren's Syndrometreatment2completed
NCT03840538
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Use of Well Known Drugs for New Destination - RA Improvement (RANT)treatment1completed
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Treatment of Dry Eye Using 0.03% Tacrolimus Eye Dropstreatment4completed
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Green Tea Lozenges for the Management of Dry MouthNo drug interventionstreatment1 / 2completed
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Biopsy Based Study to Understand Mechanism of Action of Ianalumab in Salivary Glands and Explore Relationships With Clinical Assessments.treatment2active_not_recruiting
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Minor Salivary Gland Transplantation for Cicatrizing ConjunctivitisNo drug interventionstreatmentNot Availableunknown_status
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Nivolumab in Treating Patients With Autoimmune Disorders and Advanced, Metastatic, or Unresectable Cancertreatment1recruiting
NCT03865888
Comparing Effect of Topical Tacrolimus 0.03% Versus Cyclosporine 0.05% in Dry Eyes of Secondary Sjogren Syndrometreatment3completed
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Cross-sectional Study of Use of Speckle Method in Early Diagnosis of Cardiovascular DysfunctionNo drug interventionsNot AvailableNot Availableunknown_status
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Pregnancy and Medically Assisted Conception in Rare DiseasesNo drug interventionsNot AvailableNot Availablerecruiting
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Platelet -Rich Plasma (PRP) Injection for the Treatment of Severe Dry Eyetreatment3completed
NCT05350072
Two-arm Study to Assess Efficacy and Safety of Ianalumab (VAY736) in Patients With Active Sjogren's Syndrometreatment3active_not_recruiting
NCT05349214
Three-arm Study to Assess Efficacy and Safety of Ianalumab (VAY736) in Patients With Active Sjogren's Syndrometreatment3active_not_recruiting