Biperiden is a muscarinic receptor antagonist used to treat parkinsonism and control extrapyramidal side effects of neuroleptic drugs. A muscarinic antagonist that has effects in both the central and peripheral nervous systems.
- Mechanism
- Curator reviewed
Parkinsonism is thought to result from an imbalance between the excitatory (cholinergic) and inhibitory (dopaminergic) systems in the corpus striatum. The mechanism of action of centrally active anticholinergic drugs such as biperiden is considered to relate to competitive antagonism of acetylcholine at cholinergic receptors in the corpus striatum, which then restores the balance.
- Primary indication
- For use as an adjunct in the therapy of all forms of parkinsonism and control of extrapyramidal disorders secondary to neuroleptic drug therapy.Curator reviewed · 6 structured indications
- Formula / weight
- C21H29NO · 311.4611 g/mol (avg)
- First approval
- Canada, 2001 · United States, 1996
- Code names
- KL 373
Resolves to
YSXKPIUOCJLQIE-UHFFFAOYSA-NSMILESOC(CCN1CCCCC1)(C1CC2CC1C=C2)C1=CC=CC=C1What you can answer from here — as of September 20, 2026
Which drugs share a target with Biperiden, and which of those have an active Phase 3 trial?
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