Vaccine against Lyme disease that contains lipoprotein OspA, an outer surface protein of Borrelia burgdorferi sensu stricto ZS7, as expressed by Escherichia coli. Lipoprotein OspA is a single polypeptide chain... Lipoprotein OspA is a single polypeptide chain of 257 amino acids with lipids covalently bonded to the N terminus.
- Mechanism
- Curator reviewed
OspA lipoprotein, an outer surface protein of the bacteria Borrelia burgdorferi sensu stricto ZS7, is used to stimulate the production of specific antibodies against B. burgdorferi. It is used as a vaccination against Lyme Disease, a disease carried by ticks.
- Primary indication
- For prophylactic treatment of Lyme DiseaseCurator reviewed
- Also known as
- Lipoprotein OspA antigen recombinant · Lipoprotein outer surface a borrelia burgdorferi antigen · OspA lipoprotein
Resolves to
What you can answer from here — as of July 17, 2026
Which drugs share a target with Lyme disease vaccine (recombinant OspA), and which of those have an active Phase 3 trial?
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