Toll-like receptor 2

BE0001164ProteinHumansTLR2

Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. It is acted on by 18 drugs in DrugBank.

Gene name
TLR2
UniProtKB entry
O60603Swiss-Prot
Cellular location
Membrane
Residues / weight
784 residues · 89,837 Da
Also known as
TIL4 · Toll/interleukin-1 receptor-like protein 4

Resolves to

Protein
UniProtO60603UniProt nameTLR2_HUMAN
Gene
HGNCHGNC:11848NCBI Gene7097GenBank3132528GeneCardsTLR2
Pharmacology
IUPHAR/GtoPdb1752KEGGhsa:7097
Structure
PDB1FYWPDB1FYXPDB1O77
Drugs

What you can answer from here — as of September 07, 2019

18DrugsApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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35GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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46+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Toll-like receptor 2, how selective are they, and which programs against it are still in active trials?

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