Dydrogesterone

DB00378ApprovedInvestigationalWithdrawnSmall molecule

Dydrogesterone is a synthetic progesterone for menstrual cycle regulation, infertility treatment, prevention of miscarriage, and other conditions. A synthetic progestational hormone with no androgenic or estrogenic properties.

Chemical structure of Dydrogesterone
Mechanism
Curator reviewed
Primary indication
Used to treat irregular duration of cycles and irregular occurrence and duration of periods caused by progesterone deficiency.Curator reviewed · 6 structured indications
Formula / weight
C21H28O2 · 312.4458 g/mol (avg)
Also known as
Didrogesterone · Gestatron · Hydrogesterone · Hydrogestrone · Isopregnenone
Code names
NSC-92336

Resolves to

Compound
UNII90I02KLE8KCAS152-62-5ChEMBLCHEMBL1200853ChEBI31527PubChem9051KEGGD01217
Clinical / RWD
RxNorm3706ATCG03DB01ATCG03FA14ATCG03FB08PharmGKBPA164745443
Structure
InChIKeyJGMOKGBVKVMRFX-HQZYFCCVSA-NSMILES[H][C@@]12CC[C@H](C(C)=O)[C@@]1(C)CC[C@]1([H])[C@@]2([H])C=CC2=CC(=O)CC[C@@]12C
Targets
P06401PGR

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
209Drug interactionsStructured to mechanism, not free text
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87Clinical trialsPhase, status and sponsor resolved per trial
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6Structured indicationsCondition, population, route and combination as fields, not prose
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6ContraindicationsEach with its own population and attribute set
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82Marketed productsAcross 9 countries and 16 labellers
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3ATC codesIncluding every combination product, plus 15 drug categories
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10+ReferencesStructured and connected to the statements they support
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