DB00522ApprovedWithdrawnSmall molecule
Bentiromide is a dipeptide that is used in the bentiromide test, which is a screening test for evaluating pancreatic exocrine function and monitoring the adequacy of supplemental pancreatic therapy. It... It is typically administered orally.
- Mechanism
- Curator reviewed
Bentiromide is a peptide that is broken down in the pancreas by chymotrypsin. By determining the output of unchanged bentiromide in the urine following oral administration, it is possible to determine the sufficiency of pancreatic activity.
- Primary indication
- Indicated as a screening test for exocrine pancreatic insufficiency and to monitor the adequacy of supplemental pancreatic therapy.Curator reviewed
- Formula / weight
- C23H20N2O5 · 404.4153 g/mol (avg)
- Also known as
- BTPABA
- Code names
- E-2663 · Ro 11-7891
Resolves to
Clinical / RWD
Structure
InChIKey
SPPTWHFVYKCNNK-FQEVSTJZSA-NSMILESOC(=O)C1=CC=C(NC(=O)[C@H](CC2=CC=C(O)C=C2)NC(=O)C2=CC=CC=C2)C=C1Targets
What you can answer from here — as of September 13, 2026
Which drugs share a target with Bentiromide, and which of those have an active Phase 3 trial?
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