Deslanoside

Star0

DB01078ApprovedSmall molecule

Deacetyllanatoside C. A cardiotonic glycoside from the leaves of Digitalis lanata.

Mechanism: Deslanoside inhibits the Na-K-ATPase membrane pump, resulting in an increase in intracellular sodium and calcium concentrations. Increased intracellular concentrations of calcium may promote activation of contractile proteins (e.g., actin, myosin). Deslanoside also acts on the electrical activity of the heart, increasing the slope of phase 4 depolarization, shortening the action potential duration, and decreasing the maximal diastolic potential.
Curator reviewed
Primary indication: For the treatment and management of Congestive cardiac insufficiency, arrhythmias and heart failure.Curator reviewed
Formula / weight: C₄₇H₇₄O₁₉ · 943.0791 g/mol (avg)
Also known as: Deacetyllanatoside C · Desacetyllanatoside C · Glucodigoxin

Resolves to

Compound

UNIIYGY317RK75CAS17598-65-1ChEMBLCHEMBL1614ChEBI31468PubChem28620KEGGD01240

Clinical / RWD

RxNorm3248ATCC01AA07PharmGKBPA164747478

Structure

InChIKeyOBATZBGFDSVCJD-LALPQLPRSA-NSMILES

C[C@H]1O[C@H](C[C@H](O)[C@@H]1O[C@H]1C[C@H](O)[C@H](O[C@H]2C[C@H](O)[C@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](C)O2)[C@@H](C)O1)O[C@H]1CC[C@@]2(C)[C@H](CC[C@@H]3[C@@H]2C[C@@H](O)[C@]2(C)[C@H](CC[C@]32O)C2=CC(=O)OC2)C1

Targets

P05023ATP1A1

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

509Drug interactionsStructured to mechanism, not free text

1ATC codeIncluding every combination product, plus 16 drug categories

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with Deslanoside, and which of those have an active Phase 3 trial?

Answer this in Biopharma OS Sign in to your account

Create a free account or log in to explore the full data card.

Create Account