Emedastine is a selective H1-receptor antagonist used topically to manage symptoms of allergic conjunctivitis. A medication used in eye drops to relieve eye allergy symptoms such as itchiness.
- Mechanism
- Curator reviewed
Emedastine is a relatively selective, histamine H1 antagonist. In vitro examinations of emedastine's affinity for histamine receptors demonstrate relative selectivity for the H1 histamine receptor. In vivo studies have shown concentration-dependent inhibition of histamine-stimulated vascular permeability in the conjunctiva following topical ocular administration. Emedastine appears exert negligible effects on adrenergic, dopaminergic and serotonin receptors.
- Primary indication
- For the temporary relief of the signs and symptoms of allergic conjunctivitis.Curator reviewed · 1 structured indication
- Formula / weight
- C17H26N4O · 302.4145 g/mol (avg)
- First approval
- Canada, 1998 · United States, 1998 · European Union, 2016
- Brand names
Resolves to
KBUZBQVCBVDWKX-UHFFFAOYSA-NSMILESCCOCCN1C(=NC2=CC=CC=C12)N1CCCN(C)CC1What you can answer from here — as of September 13, 2026
Which drugs share a target with Emedastine, and which of those have an active Phase 3 trial?
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