Histamine H1 Inhibitors

Name
Histamine H1 Inhibitors
Accession Number
DBCAT003399
Description
Not Available
Drugs
DrugDrug Description
EpinastineAn H1 receptor antagonist used to prevent itching in allergic conjunctivitis.
OlopatadineA histamine H1 antagonist used to treat allergic conjunctivitis and rhinitis.
KetotifenA histamine H1 receptor blocker used to treat mild asthma and allergic conjunctivitis.
EmedastineA selective H1-receptor antagonist used topically to manage symptoms of allergic conjunctivitis.
Drugs & Drug Targets
DrugTargetType
EpinastineHistamine H1 receptortarget
EpinastineHistamine H2 receptortarget
EpinastineAlpha-1A adrenergic receptortarget
EpinastineAlpha-2A adrenergic receptortarget
Epinastine5-hydroxytryptamine receptor 2Atarget
Epinastine5-hydroxytryptamine receptor 7target
EpinastineP-glycoprotein 1transporter
EpinastineCytochrome P450 2B6enzyme
EpinastineCytochrome P450 2D6enzyme
EpinastineCytochrome P450 3A4enzyme
OlopatadineHistamine H1 receptortarget
OlopatadineProtein S100-A1target
OlopatadineProtein S100-A12target
OlopatadineProtein S100-Btarget
OlopatadineProtein S100-A13target
OlopatadineProtein S100-A2target
OlopatadineCytochrome P450 3A4enzyme
OlopatadineSerum albumincarrier
OlopatadineDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
OlopatadineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
OlopatadineP-glycoprotein 1transporter
OlopatadineHistamine H2 receptortarget
OlopatadineHistamine H3 receptortarget
KetotifenHistamine H1 receptortarget
Ketotifen6-phosphogluconate dehydrogenase, decarboxylatingtarget
EmedastineHistamine H1 receptortarget