DB01581ApprovedVet approvedWithdrawnSmall molecule
Sulfamerazine is an antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections.
- Mechanism
- Curator reviewed
Sulfamerazine is a sulfonamide drug that inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for binding to dihydropteroate synthetase (dihydrofolate synthetase). Sulfamerazine is bacteriostatic in nature. Inhibition of dihydrofolic acid synthesis decreases the synthesis of bacterial nucleotides and DNA.
- Primary indication
- A sulfanilamide that is used as an antibacterial agent.Curator reviewed · 14 structured indications
- Formula / weight
- C11H12N4O2S · 264.304 g/mol (avg)
- First approval
- Canada, 1959
- Also known as
- Sulfamethyldiazine · Sulphamerazine
Resolves to
Structure
InChIKey
QPPBRPIAZZHUNT-UHFFFAOYSA-NSMILESCC1=NC(NS(=O)(=O)C2=CC=C(N)C=C2)=NC=C1Targets
What you can answer from here — as of September 13, 2026
1Protein targetEach mapped to UniProt, with action and pharmacological actionListed above
Which drugs share a target with Sulfamerazine, and which of those have an active Phase 3 trial?
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