8-azaguanine

DB01667ExperimentalSmall molecule

8-azaguanine is one of the early purine analogs showing antineoplastic activity. It functions as an antimetabolite and is easily incorporated into ribonucleic acids.

Formula / weight: C₄H₄N₆O · 152.1142 g/mol (avg)
Also known as: Azaguanine · Azaguanine-8 · Guanazol · Pathocidin · Pathocidine
Code names: B-28 · SF-337 · SK 1150

Resolves to

Compound

UNIIQ150359I72CAS134-58-7ChEMBLCHEMBL374107ChEBI63486PubChem8646

Structure

InChIKeyLPXQRXLUHJKZIE-UHFFFAOYSA-NSMILESNC1=NC2=C(N=NN2)C(=O)N1

Targets

P00491PNP

What you can answer from here — as of September 13, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

640Drug interactionsStructured to mechanism, not free text

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with 8-azaguanine, and which of those have an active Phase 3 trial?

Answer this in Biopharma OS Sign in to your account

Create a free account or log in to explore the full data card.

Create Account