Piretanide

DB02925ApprovedSmall molecule

Piretanide is a loop diuretic used to manage essential arterial hypertension and edema cardiac, hepatic, and renal origin. Piretanide (INN, trade names Arelix, Eurelix, Tauliz) has been synthesized in 1973 at Hoechst AG (Germany) as a loop diuretic compound by using a then-new method for introducing cyclic amine residues in an aromatic nucleus...

Chemical structure of Piretanide
Mechanism
Curator reviewed
Formula / weight
C17H18N2O5S · 362.4 g/mol (avg)
Code names
HOE-118 · S-73-4118

Resolves to

Compound
UNIIDQ6KK6GV93CAS55837-27-9ChEMBLCHEMBL349803ChEBI32015PubChem4849KEGGD01634
Clinical / RWD
RxNorm33770ATCC03CA03ATCG01AE10
Structure
InChIKeyUJEWTUDSLQGTOA-UHFFFAOYSA-NSMILESNS(=O)(=O)C1=CC(=CC(N2CCCC2)=C1OC1=CC=CC=C1)C(O)=O
Targets
Q13621SLC12A1

What you can answer from here — as of September 13, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
981Drug interactionsStructured to mechanism, not free text
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5Structured indicationsCondition, population, route and combination as fields, not prose
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16ContraindicationsEach with its own population and attribute set
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35Marketed productsAcross 2 countries and 1 labeller
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2ATC codesIncluding every combination product, plus 12 drug categories
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1+ReferenceStructured and connected to the statements they support
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