Enalkiren

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DB03395ExperimentalSmall molecule

Enalkiren: Overview.

Mechanism: Pharmacologically active on Renin
Curator reviewed
Formula / weight: C₃₅H₅₆N₆O₆ · 656.8557 g/mol (avg)
Code names: A-64662 · ABBOTT-64662

Resolves to

Compound

UNII0U7YZ42Z47CAS113082-98-7ChEMBLCHEMBL300337ChEBI4787PubChem60594KEGGD03738

Structure

InChIKeyKQXVERRYBYGQJZ-WRPDIKACSA-NSMILESCOC1=CC=C(C[C@H](NC(=O)CC(C)(C)N)C(=O)N[C@@H](CC2=CN=CN2)C(=O)N[C@@H](CC2CCCCC2)[C@@H](O)[C@@H](O)CC(C)C)C=C1

Targets

P00797REN

What you can answer from here — as of September 13, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

16Drug interactionsStructured to mechanism, not free text

6+ReferencesStructured and connected to the statements they support

Which drugs share a target with Enalkiren, and which of those have an active Phase 3 trial?

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