Clofedanol

DB04837ApprovedWithdrawnSmall moleculeAntitussive Agents

Clofedanol is an antitussive used for the symptomatic relief of acute cough caused by minor throat and bronchial irritation. Clofedanol is a centrally-acting cough suppressant available in Canada under the trade name Ulone.

Chemical structure of Clofedanol
Mechanism
Curator reviewed
Primary indication
Used in the treatment of dry cough.Curator reviewed · 1 structured indication
Formula / weight
C17H20ClNO · 289.8 g/mol (avg)
First approval
Canada, 2022
Also known as
Chlophedianol
Brand names
  • Biclora
  • Poly Hist Pd
  • Vanacof-8

Resolves to

Compound
UNII42C50P12APCAS791-35-5ChEMBLCHEMBL1201313ChEBI135207PubChem2795
Clinical / RWD
RxNorm21254ATCR05DB10PharmGKBPA164748134
Structure
InChIKeyWRCHFMBCVFFYEQ-UHFFFAOYSA-NSMILESCN(C)CCC(O)(C1=CC=CC=C1)C1=CC=CC=C1Cl
Targets
P35367HRH1

What you can answer from here — as of September 13, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
26Drug interactionsStructured to mechanism, not free text
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1Structured indicationCondition, population, route and combination as fields, not prose
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58Marketed productsAcross 2 countries and 23 labellers
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1ATC codeIncluding every combination product, plus 8 drug categories
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3+ReferencesStructured and connected to the statements they support
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