- Antitussive Agents
- Accession Number
Agents that suppress cough. They act centrally on the medullary cough center. EXPECTORANTS, also used in the treatment of cough, act locally.
Drug Drug Description Codeine An opioid analgesic used to treat moderate to severe pain when the use of an opioid is indicated. Dextromethorphan An NMDA receptor antagonist used to treat cases of dry cough. Hydrocodone An opioid agonist used as an analgesic and antitussive agent. Methadone An opioid analgesic indicated for management of severe pain that is not responsive to alternative treatments. Also used to aid in detoxification and maintenance treatment of opioid addiction. Butorphanol An opioid agonist-antagonist used to treat moderate to severe pain. Benzonatate A non-narcotic oral antitussive drug used to suppress coughing. Ethylmorphine An opioid analgesic and antitussive agent used to reduce coughs caused by colds and lung infections in combination with codeine. Oxeladin Withdrawn from the Canadian, US, and UK markets in 1976 due to carcinogenicity. Noscapine Investigated for use/treatment in lymphoma (non-hodgkin's), leukemia (lymphoid), cancer/tumors (unspecified), and multiple myeloma. Pipazethate For the treatment of cough. Isoaminile Isoaminile, an antitussive drug with a structure similar to methadone, is also an anticholinergic with both antimuscarinic and antinicotinic properties. Fominoben Fominoben is an antitussive agent. Clobutinol Clobutinol is a cough suppressant that is withdrawn from the US and EU markets. Clobutinol may prolong the QT interval. In 2007, Clobutinol was determined to cause cardiac arrhythmia in... Pholcodine An opioid antitussive used to suppress unproductive coughing. Doxofylline Indicated for the treatment of chronic obstructive pulmonary disease (COPD), bronchial asthma and pulmonary disease with spastic bronchial component. Opium A medication used to treat moderate to severe pain. Pentoxyverine A medication used to suppress a cough in the common cold, flu, bronchitis, and sinusitis. Normethadone An opioid antitussive used to treat a cough associated with inflamed mucosa. Levodropropizine Levodropropizine is under investigation in clinical trial NCT01573663 (A Drug-Drug Interaction Study of Ambroxol and Levodropropizine). Oxolamine Oxolamine is not approved in the USA, it may be marketed elsewhere internationally as a cough suppressant . It is listed as a prescription drug in New Zealand legislation .... Guacetisal Not Annotated Zipeprol Not Annotated Dropropizine Not Annotated Dimemorfan Not Annotated Clofedanol An antitussive used for the symptomatic relief of acute cough caused by minor throat and bronchial irritation. Eucalyptol A common ingredient in mouthwash and cosmetics derived naturally from the eucalyptus plant that is frequently used to to improve symptoms of airway mucus hypersecretion. Levopropoxyphene Levopropoxyphene was used as an antitussive. An antitussive is a medication often recommended for the treatment of cough and associated respiratory tract disorders. Its enantiomer, dextropropoxyphene, presents an analgesic effect.
- Drugs & Drug Targets