Sulfathiazole

DB06147ApprovedVet approvedWithdrawnSmall molecule

Sulfathiazole is a short-acting sulfa drug. It used to be a common oral and topical antimicrobial until less toxic alternatives were discovered. It is still occasionally used, sometimes in combination... Except for those formulated for vaginal use, the FDA withdrew its approval for the use of all drug products containing sulfathiazole.

Chemical structure of Sulfathiazole
Mechanism
Curator reviewed
Primary indication
Sulfathiazole is effective against a wide range of gram positive and gram negative pathogenic microorganisms.Curator reviewed · 12 structured indications
Formula / weight
C9H9N3O2S2 · 255.317 g/mol (avg)
First approval
United States, 1983
Also known as
2-Sulfanilamidothiazole · 2-Sulfonamidothiazole · Sulfanilamidothiazole · Sulphathiazole

Resolves to

Compound
UNIIY7FKS2XWQHCAS72-14-0ChEMBLCHEMBL437ChEBI9337PubChem5340KEGGD01047
Clinical / RWD
RxNorm10193ATCD06BA02ATCG01AE10ATCJ01EB07PharmGKBPA165958356
Structure
InChIKeyJNMRHUJNCSQMMB-UHFFFAOYSA-NSMILESNC1=CC=C(C=C1)S(=O)(=O)NC1=NC=CS1
Targets
P0AC13folPQ27738dihydropteroate synthase

What you can answer from here — as of August 30, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
644Drug interactionsStructured to mechanism, not free text
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12Structured indicationsCondition, population, route and combination as fields, not prose
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8Marketed productsAcross 4 countries and 4 labellers
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3ATC codesIncluding every combination product, plus 21 drug categories
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5+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Sulfathiazole, and which of those have an active Phase 3 trial?

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