NP2

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Identification

Generic Name: NP2
DrugBank Accession Number: DB06308
Background: NP2 is a replication defective HSV-1 based gene transfer vector engineered to express human preproenkephalin. It was under investigation in clinical trial NCT01291901 (NP2 Enkephalin For Treatment of Intractable Cancer Pain).
Type: Small Molecule
Groups: Investigational
Synonyms: Not Available

Pharmacology

Indication: Investigated for use/treatment in pain (acute or chronic).

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Pharmacodynamics: Not Available
Mechanism of action: NP2 is the first drug developed for use in Diamyd Medical's Nerve Targeting Drug Delivery System (NTDDS) gene therapy platform to treat chronic pain associated with cancer. NP2 produces localized enkaphalins (endogenous pain killing compounds) at the synapses between the peripheral and central nervous system neurons.
Absorption: Not Available
Volume of distribution: Not Available
Protein binding: Not Available
Metabolism: Not Available
Route of elimination: Not Available
Half-life: Not Available
Clearance: Not Available
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Toxicity: Not Available
Pathways: Not Available
Pharmacogenomic Effects/ADRs: Not Available

Interactions

Drug Interactions: This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions: Not Available

Chemical Identifiers

UNII: Not Available
CAS number: Not Available
InChI Key: Not Available
InChI: Not Available
IUPAC Name: Not Available
SMILES: Not Available

References

General References: Not Available
External Links: Not Available

Clinical Trials

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Phase	Status	Purpose	Conditions	Count	Start Date	Why Stopped	100+ additional columns
Unlock 175K+ rows when you subscribe.View sample data
2	Completed	Treatment	Intractable Pain / Neoplasm	1	somestatus	stop reason	just information to hide
1	Completed	Treatment	Cancer Pain	1	somestatus	stop reason	just information to hide

Pharmacoeconomics

Manufacturers: Not Available
Packagers: Not Available
Dosage Forms: Not Available
Prices: Not Available
Patents: Not Available

Properties

State: Solid
Experimental Properties: Not Available
Predicted Properties: Not Available
Predicted ADMET Features: Not Available

Spectra

Mass Spec (NIST): Not Available
Spectra: Not Available
Chromatographic Properties: Collision Cross Sections (CCS)
Not Available

Drug created at March 19, 2008 16:23 / Updated at August 07, 2024 07:51

NP2