alpha-Hydroxy glycineamide

DB06568ExperimentalSmall molecule

Alpha-hydroxy glycineamide (αHGA) is the active antiviral metabolite of tri-peptide glycyl-prolyl-glycine-amide (GPG-NH2). αHGA inhibits the replication of HIV-1 in vitro by interfering with the capsid formation. It also has an... It also has an effect on viral gp160 envelope protein.

Primary indication
Investigated for use/treatment in HIV infection.Curator reviewed
Also known as
aHGA · alfaHGA · alpha-HGA · alphaHGA

What you can answer from here — as of April 02, 2025

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Which companies are running trials of alpha-Hydroxy glycineamide, in which indications and phases, and which of those programs are still active?

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