Envelope glycoprotein gp160

BE0002838ProteinHIV-1env

Envelope glycoprotein gp160 Oligomerizes in the host endoplasmic reticulum into predominantly trimers. It is acted on by 14 drugs in DrugBank.

Gene name
env
UniProtKB entry
P12488Swiss-Prot
Cellular location
Virion membrane
Residues / weight
852 residues · 97,203 Da
Also known as
Env polyprotein

Resolves to

Protein
UniProtP12488UniProt nameENV_HV1BN
Structure
PDB1IM7PDB1J8NPDB1J8Z
Drugs

What you can answer from here — as of September 07, 2019

14DrugsApproved to experimental, with action, bond type and pharmacological action
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16GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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33+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Envelope glycoprotein gp160, how selective are they, and which programs against it are still in active trials?

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