Hydroxyproline

DB08847ApprovedSmall molecule

Hydroxyproline is a neutral heterocyclic protein amino acid. It is found in collagen and as such it is common in many gelatin products. Hydroxyproline is mostly used as a diagnostic... Hydroxyproline is mostly used as a diagnostic marker of bone turnover and liver fibrosis.

Chemical structure of Hydroxyproline
Primary indication
Used in France as a combination product for the treatment of small, superficial wounds.Curator reviewed
Formula / weight
C5H9NO3 · 131.1299 g/mol (avg)
Also known as
trans-L-Hydroxyproline

Resolves to

Compound
UNIIRMB44WO89XCAS51-35-4ChEMBLCHEMBL352418ChEBI18095PubChem5810KEGGC01157
Clinical / RWD
RxNorm1311548
Structure
InChIKeyPMMYEEVYMWASQN-DMTCNVIQSA-NSMILESO[C@H]1CN[C@@H](C1)C(O)=O
Transporters
Q7Z2H8SLC36A1Q495M3SLC36A2

What you can answer from here — as of August 22, 2026

2TransportersSubstrate / inhibitor direction, not just membership
Listed above
1Clinical trialPhase, status and sponsor resolved per trial
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34Marketed productsAcross 1 country and 1 labeller
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21+ReferencesStructured and connected to the statements they support
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Which companies are running trials of Hydroxyproline, in which indications and phases, and which of those programs are still active?

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