Fendiline

DB08980ApprovedWithdrawnSmall molecule

Fendiline is a coronary vasodilator which inhibits calcium function in muscle cells in excitation-contraction coupling. It has been proposed as an antiarrhythmic and antianginal agent. Fendiline is non-selective.

Chemical structure of Fendiline
Formula / weight
C23H25N · 315.4513 g/mol (avg)

Resolves to

Compound
UNIIS253D559A8CAS13042-18-7ChEMBLCHEMBL254832ChEBI94434PubChem3336KEGGD07185
Clinical / RWD
RxNorm4327ATCC08EA01
Structure
InChIKeyNMKSAYKQLCHXDK-UHFFFAOYSA-NSMILESCC(NCCC(C1=CC=CC=C1)C1=CC=CC=C1)C1=CC=CC=C1
Targets
P41595HTR2B

What you can answer from here — as of August 25, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
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1,003Drug interactionsStructured to mechanism, not free text
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1Clinical trialPhase, status and sponsor resolved per trial
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3Marketed productsAcross 1 country and 3 labellers
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1ATC codeIncluding every combination product, plus 18 drug categories
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4+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Fendiline, and which of those have an active Phase 3 trial?

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