Carbon dioxide

DB09157ApprovedInvestigationalVet approvedSmall moleculeRadiographic Contrast Agent

Carbon dioxide is a naturally-occurring gas used as a insufflation gas during minimally invasive surgeries to enlarge and stabilize body cavities to provide better visibility of the surgical area. Carbon dioxide is a colorless, odorless gas vital to life on Earth.

Chemical structure of Carbon dioxide
Mechanism
Curator reviewed
Primary indication
Carbon dioxide is commonly used as an insufflation gas for minimal invasive surgery (laparoscopy, endoscopy, and arthroscopy) to enlarge and stabilize body cavities to provide better visibility of the surgical area.Curator reviewed · 12 structured indications
Formula / weight
CO2 · 44.0095 g/mol (avg)
First approval
Canada, 2020 · United States, 1960
Code names
E-290 · INS-290 · INS NO.290

Resolves to

Compound
UNII142M471B3JCAS124-38-9ChEMBLCHEMBL1231871ChEBI16526PubChem280KEGGD00004
Clinical / RWD
RxNorm2034ATCV03AN02PharmGKBPA448801
Structure
InChIKeyCURLTUGMZLYLDI-UHFFFAOYSA-NSMILESO=C=O
Transporters
P02730SLC4A1

What you can answer from here — as of July 03, 2026

1TransporterSubstrate / inhibitor direction, not just membership
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34Clinical trialsPhase, status and sponsor resolved per trial
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12Structured indicationsCondition, population, route and combination as fields, not prose
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185Marketed productsAcross 4 countries and 68 labellers
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1ATC codeIncluding every combination product, plus 10 drug categories
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8+ReferencesStructured and connected to the statements they support
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Which other approved drugs treat the same conditions as Carbon dioxide, and which companies have late-stage candidates in those indications?

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