Caroxazone

DB09254ApprovedWithdrawnSmall molecule

Caroxazone is an antidepressant that has been withdrawn from the market. It is a reversible monoamine oxidase inhibitor (MAOI) of both A and B monoamine oxidase subtypes. However, it presents... However, it presents a five-fold preference for the MAO-B subtype.

Mechanism: Pharmacologically active on Amine oxidase [flavin-containing] B
Curator reviewed
Primary indication: For the treatment of depression.Curator reviewed
Formula / weight: C₁₀H₁₀N₂O₃ · 206.201 g/mol (avg)
Code names: F.I. 6654

Resolves to

Compound

UNII807N226MNLCAS18464-39-6ChEMBLCHEMBL2104164ChEBI134867PubChem29083

Structure

InChIKeyKYCBWEZLKCTALM-UHFFFAOYSA-NSMILESNC(=O)CN1CC2=CC=CC=C2OC1=O

Targets

P27338MAOB

What you can answer from here — as of July 03, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

1,331Drug interactionsStructured to mechanism, not free text

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with Caroxazone, and which of those have an active Phase 3 trial?

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