Chlorine

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Chlorine
DrugBank Accession Number
DB11109
Background

Chlorine is a stongly oxidizing agent and the third most electronegative element which belongs to the group of halogens with the atomic number 17 and symbol Cl. Being a yellow-green gas at room temperature, chlorine is the second most abundant halogen on Earth. It is commonly used in sanitation, disinfection and antiseptic processes. It was also used in chemical warfare and in rocket fuel.

Type
Small Molecule
Groups
Experimental
Structure
Weight
Average: 70.906
Monoisotopic: 69.937705414
Chemical Formula
Cl2
Synonyms
  • Chlor
  • Chlore
  • Cloro
  • Dichlorine

Pharmacology

Indication

Not Available

Reduce drug development failure rates
Build, train, & validate machine-learning models
with evidence-based and structured datasets.
See how
Build, train, & validate predictive machine-learning models with structured datasets.
See how
Associated Therapies
Contraindications & Blackbox Warnings
Prevent Adverse Drug Events Today
Tap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.
Learn more
Avoid life-threatening adverse drug events with our Clinical API
Learn more
Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Improve decision support & research outcomes
With structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!
See the data
Improve decision support & research outcomes with our structured adverse effects data.
See a data sample
Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

Drug product information from 10+ global regions
Our datasets provide approved product information including:
dosage, form, labeller, route of administration, and marketing period.
Access now
Access drug product information from over 10 global regions.
Access now
Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
Clorpactin WCS-90Powder, for solution0.16 g/2gTopicalUnited-Guardian, Inc.1955-01-01Not applicableUS flag
Disinfectant(NaClO)Liquid4.2 g/100mLTopicalShanghai Rayshine ENVI-TECH Developing CO., Ltd.2020-04-19Not applicableUS flag
HBA DisinfectantSpray200 mg/1000mLTopicalHenan Huibo Medical Co., Ltd.2020-07-22Not applicableUS flag
Trichloroisocyanuric AcidLiquid91 kg/100kgTopicalGUANGZHOU YIQI TECHNOLOGY CO.,LTD2020-12-15Not applicableUS flag
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
NUTRIFLEX LIPID PERI INFUZYONLUK IV EMULSIYON, 1870 MLChlorine (72 mmol) + Acetate (60 mmol) + Alanine (7.28 g) + Arginine (4.05 g) + Aspartic acid (2.25 g) + Calcium (4.5 mmol) + Calcium chloride dihydrate (0.662 g) + D-glucose (120 g) + Glutamic acid (5.25 g) + Glycine (2.48 g) + Histidine (1.88 g) + Isoleucine (3.51 g) + Leucine (4.7 g) + Lysine (3.39 g) + Magnesium (4.5 mmol) + Magnesium acetate tetrahydrate (0.966 g) + Medium-chain triglycerides (37.5 g) + Methionine (2.94 g) + Phenylalanine (5.27 g) + Potassium (45 mmol) + Potassium acetate (4.415 g) + Proline (5.1 g) + Serine (4.5 g) + Sodium acetate trihydrate (0.816 g) + Sodium cation (75 mmol) + Sodium chloride (1.622 g) + Sodium hydroxide (1.2 g) + Sodium phosphate, monobasic, dihydrate (1.755 g) + Soybean oil (37.5 g) + Threonine (2.73 g) + Tryptophan (0.86 g) + Valine (3.9 g) + Zinc (0.045 mmol) + Zinc acetate dihydrate (9.938 mg)Injection, emulsionIntravenousB.BRAUN MEDİKAL DIŞ TİC. A.Ş.2005-11-162018-10-12Turkey flag
NUTRIFLEX LIPID PERI INFUZYONLUK IV EMULSIYON, 2500 MLChlorine (96 mmol) + Acetate (80 mmol) + Alanine (9.7 g) + Arginine (5.4 g) + Aspartic acid (3 g) + Calcium (6 mmol) + Calcium chloride dihydrate (0.882 g) + D-glucose (160 g) + Glutamic acid (7 g) + Glycine (3.3 g) + Histidine (2.5 g) + Isoleucine (4.68 g) + Leucine (6.26 g) + Lysine (4.52 g) + Magnesium (6 mmol) + Magnesium acetate tetrahydrate (1.288 g) + Medium-chain triglycerides (50 g) + Methionine (3.92 g) + Phenylalanine (7.02 g) + Potassium (60 mmol) + Potassium acetate (5.886 g) + Proline (6.8 g) + Serine (6 g) + Sodium acetate trihydrate (1.088 g) + Sodium cation (100 mmol) + Sodium chloride (2.162 g) + Sodium hydroxide (1.6 g) + Sodium phosphate, monobasic, dihydrate (2.34 g) + Soybean oil (50 g) + Threonine (3.64 g) + Tryptophan (1.14 g) + Valine (5.2 g) + Zinc (0.06 mmol) + Zinc acetate dihydrate (13.25 mg)Injection, emulsionIntravenousB.BRAUN MEDİKAL DIŞ TİC. A.Ş.2020-08-142018-10-12Turkey flag
NUTRIFLEX LIPID PLUS INFUZYONLUK EMULSIYON, 1250 MLChlorine (45 mmol) + Acetate (45 mmol) + Alanine (5.82 g) + Arginine (3.24 g) + Aspartic acid (1.8 g) + Calcium (4 mmol) + Calcium chloride dihydrate (0.588 g) + D-glucose (150 g) + Glutamic acid (4.21 g) + Glycine (1.98 g) + Histidine (1.5 g) + Isoleucine (2.82 g) + Leucine (3.76 g) + Lysine (2.73 g) + Magnesium (4 mmol) + Magnesium acetate tetrahydrate (0.858 g) + Medium-chain triglycerides (25 g) + Methionine (2.35 g) + Phenylalanine (4.21 g) + Phosphate ion (15 mmol) + Potassium (35 mmol) + Potassium acetate (3.434 g) + Proline (4.08 g) + Serine (3.6 g) + Sodium acetate trihydrate (0.277 g) + Sodium cation (50 mmol) + Sodium chloride (0.503 g) + Sodium hydroxide (0.976 g) + Sodium phosphate, monobasic, dihydrate (2.34 g) + Soybean oil (25 g) + Threonine (2.18 g) + Tryptophan (0.68 g) + Valine (3.12 g) + Zinc (0.03 mmol) + Zinc acetate dihydrate (6.58 mg)Injection, emulsionIntravenousB.BRAUN MEDİKAL DIŞ TİC. A.Ş.2005-11-162018-10-03Turkey flag
NUTRIFLEX LIPID PLUS INFUZYONLUK EMULSIYON, 1870 MLChlorine (67.5 mmol) + Acetate (67.5 mmol) + Alanine (8.73 g) + Arginine (4.86 g) + Aspartic acid (2.7 g) + Calcium (6 mmol) + Calcium chloride dihydrate (0.882 g) + D-glucose (225 g) + Glutamic acid (6.32 g) + Glycine (2.97 g) + Histidine (2.25 g) + Isoleucine (4.23 g) + Leucine (5.64 g) + Lysine (4.1 g) + Magnesium (6 mmol) + Magnesium acetate tetrahydrate (1.287 g) + Medium-chain triglycerides (37.5 g) + Methionine (3.53 g) + Phenylalanine (6.32 g) + Phosphate ion (22.5 mmol) + Potassium (52.5 mmol) + Potassium acetate (5.151 g) + Proline (6.12 g) + Serine (5.4 g) + Sodium acetate trihydrate (0.416 g) + Sodium cation (75 mmol) + Sodium chloride (0.755 g) + Sodium hydroxide (1.464 g) + Sodium phosphate, monobasic, dihydrate (3.51 g) + Soybean oil (37.5 g) + Threonine (3.27 g) + Tryptophan (1.02 g) + Valine (4.68 g) + Zinc (0.045 mmol) + Zinc acetate dihydrate (9.87 mg)Injection, emulsionIntravenousB.BRAUN MEDİKAL DIŞ TİC. A.Ş.2005-11-162018-10-03Turkey flag
NUTRIFLEX LIPID PLUS INFUZYONLUK EMULSIYON, 2500 MLChlorine (90 mmol) + Acetate (90 mmol) + Alanine (11.64 g) + Arginine (6.48 g) + Aspartic acid (3.6 g) + Calcium (8 mmol) + Calcium chloride dihydrate (1.176 g) + D-glucose (300 g) + Glutamic acid (8.42 g) + Glycine (3.96 g) + Histidine (3 g) + Isoleucine (5.64 g) + Leucine (7.52 g) + Lysine (5.46 g) + Magnesium (8 mmol) + Magnesium acetate tetrahydrate (1.716 g) + Medium-chain triglycerides (50 g) + Methionine (4.7 g) + Phenylalanine (8.42 g) + Phosphate ion (30 mmol) + Potassium (70 mmol) + Potassium acetate (6.868 g) + Proline (8.16 g) + Serine (7.2 g) + Sodium acetate trihydrate (0.554 g) + Sodium cation (100 mmol) + Sodium chloride (1.006 g) + Sodium hydroxide (1.952 g) + Sodium phosphate, monobasic, dihydrate (4.68 g) + Soybean oil (50 g) + Threonine (4.36 g) + Tryptophan (1.36 g) + Valine (6.24 g) + Zinc (0.06 mmol) + Zinc acetate dihydrate (13.16 mg)Injection, emulsionIntravenousB.BRAUN MEDİKAL DIŞ TİC. A.Ş.2020-08-142018-10-03Turkey flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Clorpactin WCS-90Chlorine (0.16 g/2g)Powder, for solutionTopicalUnited-Guardian, Inc.1955-01-01Not applicableUS flag
Disinfectant(NaClO)Chlorine (4.2 g/100mL)LiquidTopicalShanghai Rayshine ENVI-TECH Developing CO., Ltd.2020-04-19Not applicableUS flag
HBA DisinfectantChlorine (200 mg/1000mL)SprayTopicalHenan Huibo Medical Co., Ltd.2020-07-22Not applicableUS flag
Sub small molecule disinfectantChlorine (0.0076 g/38g) + Calcium (0.038 g/38g)LiquidExtracorporealGUANGZHOU KARLSBRAU Biotechnology Co., Ltd2020-02-01Not applicableUS flag
Trichloroisocyanuric AcidChlorine (91 kg/100kg)LiquidTopicalGUANGZHOU YIQI TECHNOLOGY CO.,LTD2020-12-15Not applicableUS flag

Categories

Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of inorganic compounds known as homogeneous halogens. These are inorganic non-metallic compounds in which the largest atom is a nobel gas.
Kingdom
Inorganic compounds
Super Class
Homogeneous non-metal compounds
Class
Homogeneous halogens
Sub Class
Not Available
Direct Parent
Homogeneous halogens
Alternative Parents
Inorganic chloride salts
Substituents
Homogeneous halogen / Inorganic chloride salt / Inorganic salt
Molecular Framework
Not Available
External Descriptors
diatomic chlorine (CHEBI:29310)
Affected organisms
Not Available

Chemical Identifiers

UNII
4R7X1O2820
CAS number
7782-50-5
InChI Key
KZBUYRJDOAKODT-UHFFFAOYSA-N
InChI
InChI=1S/Cl2/c1-2
IUPAC Name
dichlorine
SMILES
ClCl

References

General References
Not Available
PubChem Compound
24526
PubChem Substance
347827900
ChemSpider
22933
RxNav
1310122
ChEBI
29310
Wikipedia
Chlorine

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4CompletedPreventionOral Health1
2, 3Active Not RecruitingSupportive CareAdvanced Malignant Neoplasm / Delirium / Locally advanced Malignant Neoplasms / Metastatic Cancer / Recurrent Malignant Neoplasm1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Powder, for solutionTopical0.16 g/2g
LiquidTopical4.2 g/100mL
SprayTopical200 mg/1000mL
Injection, emulsionIntravenous
EmulsionIntravenous
SolutionIntraperitoneal
LiquidExtracorporeal
LiquidTopical91 kg/100kg
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility31.0 mg/mLALOGPS
logP0.98ALOGPS
logP1.08Chemaxon
logS-0.36ALOGPS
Physiological Charge0Chemaxon
Hydrogen Acceptor Count0Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area0 Å2Chemaxon
Rotatable Bond Count0Chemaxon
Refractivity12.27 m3·mol-1Chemaxon
Polarizability4.55 Å3Chemaxon
Number of Rings0Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Mass Spectrum (Electron Ionization)MSsplash10-00dr-9000000000-3cbc095f1caa401edb8c
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-00di-9000000000-10127e6b10c0dfc2fcc5
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-00di-9000000000-10127e6b10c0dfc2fcc5
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-00di-9000000000-10127e6b10c0dfc2fcc5
Chromatographic Properties
Collision Cross Sections (CCS)
AdductCCS Value (Å2)Source typeSource
[M-H]-111.62628
predicted
DeepCCS 1.0 (2019)
[M+H]+113.401886
predicted
DeepCCS 1.0 (2019)
[M+Na]+120.348
predicted
DeepCCS 1.0 (2019)

Drug created at December 03, 2015 16:51 / Updated at June 12, 2020 16:53