Boron

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Boron
DrugBank Accession Number
DB11203
Background

Boron (B) is a chemical element with an atomic number 5 that belongs in the Period 2 and Group 13 in the periodic table. It is a low-abundant metalloid that is a poor electrical conductor at room temperature. Natural boron exists in 2 stable isotopes however pure boron is hard to prepare due to contamination by different elements. It is also found for applications including ceramics, high-hardness or abrasive compounds, metal coatings, detergents, bleaching agents, insecticides, semiconductors, magnets, wood preservatives, and an additive in glass fibers of boron-containing fiberglass for insulation and structural materials. Boric acid contains antiseptic, antifungal, and antiviral properties thus it is used as a water clarifier in swimming pool water treatment. There are few pharmaceutical agents that contain a boron molecule in their structures, such as Tavaborole and Bortezomib.

Type
Small Molecule
Groups
Experimental
Structure
Thumb
Weight
Average: 10.81
Monoisotopic: 11.009305
Chemical Formula
B
Synonyms
  • Bor
  • Boracium
  • Bore
  • Boro

Pharmacology

Indication

Not Available

Pharmacology
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Associated Conditions
Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Medicalerrors
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
CalceminBoron (50 ug/1) + Previtamin D(3) (0.75 mg/1) + Zinc (2 mg/1)Tablet, film coatedOralBayer Healthcare Llc.2016-04-01Not applicableUS flag
Calcemin SilverBoron (2.6 mg/1) + Magnesium oxide (40 mg/1) + Zinc oxide (7.5 mg/1)Tablet, film coatedOralBayer Healthcare Llc.2016-04-01Not applicableUS flag
MENOPACE KAPSUL, 30 ADETBoron (2 mg) + Aminobenzoic acid (30 mg) + Ascorbic acid (45 mg) + Biotin (30 mcg) + Chromium picolinate (50 mcg) + Copper (1 mg) + Cyanocobalamin (9 mcg) + Folic acid (400 mcg) + Iodine (225 mcg) + Iron (12 mg) + Magnesium (100 mg) + Manganese (2 mg) + Niacin (20 mg) + Pantothenic acid (30 mg) + Pyridoxine (40 mg) + Riboflavin (5 mg) + Selenium (100 mcg) + Thiamine (10 mg) + Vitamin A (750 mcg) + Vitamin D (2.5 mcg) + Vitamin E (30 mg) + Zinc (15 mg)CapsuleOralNOBEL İLAÇ SAN. VE TİC. A.Ş.2020-08-142020-05-28Turkey flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Calcium Folic Acid Plus D ChewableBoron (250 ug/1) + Calcium carbonate (1342 mg/1) + Cholecalciferol (300 [iU]/1) + Cyanocobalamin (125 ug/1) + Folic acid (1 mg/1) + Magnesium (50 mg/1) + Pyridoxine (10 mg/1)WaferOralAcella Pharmaceuticals, LLC2009-03-20Not applicableUS flag
Folitin-ZBoron (25 ug/1) + Ascorbic acid (250 mg/1) + Biotin (100 ug/1) + Calcium carbonate (75 mg/1) + Cholecalciferol (13.75 ug/1) + Chromium nicotinate (37.5 ug/1) + Cupric oxide (1 mg/1) + Cyanocobalamin (13 ug/1) + DL-alpha tocopheryl acetate (45 mg/1) + Ferrous fumarate (9 mg/1) + Folic acid (500 ug/1) + Magnesium oxide (37.5 mg/1) + Manganese sulfate (0.75 mg/1) + Molybdenum (25 ug/1) + Nicotinamide (22.5 mg/1) + Pantothenic acid (15 mg/1) + Potassium Iodide (25 ug/1) + Potassium chloride (24.5 mg/1) + Pyridoxine hydrochloride (6 mg/1) + Riboflavin (3.35 mg/1) + Selenium (30 ug/1) + Thiamine mononitrate (3.25 mg/1) + Vitamin A acetate (1500 ug/1) + Zinc oxide (15 mg/1)TabletOralPureTek Corporation2021-02-11Not applicableUS flag
Neonatal Plus VitaminBoron (0.2 mg/1) + Ascorbic acid (20 mg/1) + Calcium (200 mg/1) + Cholecalciferol (10 ug/1) + Citrus bioflavonoids (2 mg/1) + Copper (2 mg/1) + Cyanocobalamin (12 ug/1) + Ferrous fumarate (27 mg/1) + Folic acid (1000 ug/1) + Inositol (5 mg/1) + Nicotinamide (20 mg/1) + Pyridoxine hydrochloride (10 mg/1) + Riboflavin (3 mg/1) + Thiamine chloride (1.84 mg/1) + Vitamin A (1200 ug/1) + Zinc oxide (25 mg/1) + alpha-Tocopherol acetate (9.2 mg/1)TabletOralNeomed Pharmaceutical2018-07-31Not applicableUS flag
Prenate ChewableBoron (250 ug/1) + Bilberry (25 mg/1) + Biotin (280 ug/1) + Calcium carbonate (500 mg/1) + Cholecalciferol (300 [iU]/1) + Cyanocobalamin (125 mg/1) + Folic acid (1 mg/1) + Magnesium oxide (50 mg/1) + Pyridoxine hydrochloride (10 mg/1)Tablet, chewableOralAvion Pharmaceuticals, Llc2013-01-16Not applicableUS flag
Ribotin-EBoron (25 ug/1) + Ascorbic acid (250 mg/1) + Biotin (100 ug/1) + Calcium carbonate (75 mg/1) + Cholecalciferol (13.75 ug/1) + Chromium nicotinate (37.5 ug/1) + Cupric oxide (1 mg/1) + Cyanocobalamin (13 ug/1) + DL-alpha tocopheryl acetate (45 mg/1) + Ferrous fumarate (9 mg/1) + Folic acid (500 ug/1) + Magnesium oxide (37.5 mg/1) + Manganese sulfate (0.75 mg/1) + Molybdenum (25 ug/1) + Nicotinamide (22.5 mg/1) + Pantothenic acid (15 mg/1) + Potassium Iodide (25 ug/1) + Potassium chloride (24.5 mg/1) + Pyridoxine hydrochloride (6 mg/1) + Riboflavin (3.35 mg/1) + Selenium (30 ug/1) + Thiamine mononitrate (3.25 mg/1) + Vitamin A acetate (1500 ug/1) + Zinc oxide (15 mg/1)TabletOralPureTek Corporation2021-02-11Not applicableUS flag
Zintrexyl-CBoron (25 ug/1) + Ascorbic acid (250 mg/1) + Biotin (100 ug/1) + Calcium carbonate (75 mg/1) + Cholecalciferol (13.75 ug/1) + Chromium nicotinate (37.5 ug/1) + Cupric oxide (1 mg/1) + Cyanocobalamin (13 ug/1) + DL-alpha tocopheryl acetate (45 mg/1) + Ferrous fumarate (9 mg/1) + Folic acid (500 ug/1) + Magnesium oxide (37.5 mg/1) + Manganese sulfate (0.75 mg/1) + Molybdenum (25 ug/1) + Nicotinamide (22.5 mg/1) + Pantothenic acid (15 mg/1) + Potassium Iodide (25 ug/1) + Potassium chloride (24.5 mg/1) + Pyridoxine hydrochloride (6 mg/1) + Riboflavin (3.35 mg/1) + Selenium (30 ug/1) + Thiamine mononitrate (3.25 mg/1) + Vitamin A acetate (1500 ug/1) + Zinc oxide (15 mg/1)TabletOralPureTek Corporation2021-02-11Not applicableUS flag

Categories

Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of inorganic compounds known as homogeneous metalloid compounds. These are inorganic compounds containing only metal atoms,with the largest atom being a metalloid atom.
Kingdom
Inorganic compounds
Super Class
Homogeneous metal compounds
Class
Homogeneous metalloid compounds
Sub Class
Not Available
Direct Parent
Homogeneous metalloid compounds
Alternative Parents
Not Available
Substituents
Homogeneous metalloid
Molecular Framework
Not Available
External Descriptors
boron group element atom, nonmetal atom (CHEBI:27560)
Affected organisms
Not Available

Chemical Identifiers

UNII
N9E3X5056Q
CAS number
7440-42-8
InChI Key
ZOXJGFHDIHLPTG-UHFFFAOYSA-N
InChI
InChI=1S/B
IUPAC Name
boranylidyne
SMILES
[B]

References

General References
Not Available
PubChem Compound
5462311
PubChem Substance
347827941
ChemSpider
4575371
RxNav
1705
ChEBI
27560
Wikipedia
Boron

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
3CompletedTreatmentRadiodermatitis1
2RecruitingTreatmentAdvanced Malignant Solid Neoplasm / Recurrent Malignant Solid Neoplasm1
1TerminatedTreatmentBrain and Central Nervous System Tumors1
1Unknown StatusTreatmentDiabetic Foot Ulcers (DFU)1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Tablet, film coatedOral
WaferOral
TabletOral
CapsuleOral
Tablet, chewableOral
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
logP0.33ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity0 m3·mol-1ChemAxon
Polarizability1.78 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Drug created on December 03, 2015 16:51 / Updated on June 12, 2020 16:53