Boron
This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Boron
- DrugBank Accession Number
- DB11203
- Background
Boron (B) is a chemical element with an atomic number 5 that belongs in the Period 2 and Group 13 in the periodic table. It is a low-abundant metalloid that is a poor electrical conductor at room temperature. Natural boron exists in 2 stable isotopes however pure boron is hard to prepare due to contamination by different elements. It is also found for applications including ceramics, high-hardness or abrasive compounds, metal coatings, detergents, bleaching agents, insecticides, semiconductors, magnets, wood preservatives, and an additive in glass fibers of boron-containing fiberglass for insulation and structural materials. Boric acid contains antiseptic, antifungal, and antiviral properties thus it is used as a water clarifier in swimming pool water treatment. There are few pharmaceutical agents that contain a boron molecule in their structures, such as Tavaborole and Bortezomib.
- Type
- Small Molecule
- Groups
- Experimental
- Structure
Structure for Boron (DB11203)
- Weight
- Average: 10.81
Monoisotopic: 11.009305 - Chemical Formula
- B
- Synonyms
- Bor
- Boracium
- Bore
- Boro
Pharmacology
- Indication
Not Available
Accelerate your drug discovery research with the industry’s only fully connected ADMET dataset, ideal for:Accelerate your drug discovery research with our fully connected ADMET dataset- Associated Conditions
- Contraindications & Blackbox Warnings
Contraindications & Blackbox WarningsWith our commercial data, access important information on dangerous risks, contraindications, and adverse effects.Our Blackbox Warnings cover Risks, Contraindications, and Adverse Effects- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
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Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
Comprehensive & structured drug product infoFrom application numbers to product codes, connect different identifiers through our commercial datasets.Easily connect various identifiers back to our datasets- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Calcemin Boron (50 ug/1) + Previtamin D(3) (0.75 mg/1) + Zinc (2 mg/1) Tablet, film coated Oral Bayer Healthcare Llc. 2016-04-01 Not applicable US 
Calcemin Silver Boron (2.6 mg/1) + Magnesium oxide (40 mg/1) + Zinc oxide (7.5 mg/1) Tablet, film coated Oral Bayer Healthcare Llc. 2016-04-01 Not applicable US MENOPACE KAPSUL, 30 ADET Boron (2 mg) + Aminobenzoic acid (30 mg) + Ascorbic acid (45 mg) + Biotin (30 mcg) + Chromium picolinate (50 mcg) + Copper (1 mg) + Cyanocobalamin (9 mcg) + Folic acid (400 mcg) + Iodine (225 mcg) + Iron (12 mg) + Magnesium (100 mg) + Manganese (2 mg) + Niacin (20 mg) + Pantothenic acid (30 mg) + Pyridoxine (40 mg) + Riboflavin (5 mg) + Selenium (100 mcg) + Thiamine (10 mg) + Vitamin A (750 mcg) + Vitamin D (2.5 mcg) + Vitamin E (30 mg) + Zinc (15 mg) Capsule Oral NOBEL İLAÇ SAN. VE TİC. A.Ş. 2020-08-14 2020-05-28 Turkey 
- Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Calcium Folic Acid Plus D Chewable Boron (250 ug/1) + Calcium carbonate (1342 mg/1) + Cholecalciferol (300 [iU]/1) + Cyanocobalamin (125 ug/1) + Folic acid (1 mg/1) + Magnesium (50 mg/1) + Pyridoxine (10 mg/1) Wafer Oral Acella Pharmaceuticals, LLC 2009-03-20 Not applicable US Folitin-Z Boron (25 ug/1) + Ascorbic acid (250 mg/1) + Biotin (100 ug/1) + Calcium carbonate (75 mg/1) + Cholecalciferol (13.75 ug/1) + Chromium nicotinate (37.5 ug/1) + Cupric oxide (1 mg/1) + Cyanocobalamin (13 ug/1) + DL-alpha tocopheryl acetate (45 mg/1) + Ferrous fumarate (9 mg/1) + Folic acid (500 ug/1) + Magnesium oxide (37.5 mg/1) + Manganese sulfate (0.75 mg/1) + Molybdenum (25 ug/1) + Nicotinamide (22.5 mg/1) + Pantothenic acid (15 mg/1) + Potassium Iodide (25 ug/1) + Potassium chloride (24.5 mg/1) + Pyridoxine hydrochloride (6 mg/1) + Riboflavin (3.35 mg/1) + Selenium (30 ug/1) + Thiamine mononitrate (3.25 mg/1) + Vitamin A acetate (1500 ug/1) + Zinc oxide (15 mg/1) Tablet Oral PureTek Corporation 2021-02-11 Not applicable US Neonatal Plus Vitamin Boron (0.2 mg/1) + Ascorbic acid (20 mg/1) + Calcium (200 mg/1) + Cholecalciferol (10 ug/1) + Citrus bioflavonoids (2 mg/1) + Copper (2 mg/1) + Cyanocobalamin (12 ug/1) + Ferrous fumarate (27 mg/1) + Folic acid (1000 ug/1) + Inositol (5 mg/1) + Nicotinamide (20 mg/1) + Pyridoxine hydrochloride (10 mg/1) + Riboflavin (3 mg/1) + Thiamine chloride (1.84 mg/1) + Vitamin A (1200 ug/1) + Zinc oxide (25 mg/1) + alpha-Tocopherol acetate (9.2 mg/1) Tablet Oral Neomed Pharmaceutical 2018-07-31 Not applicable US Prenate Chewable Boron (250 ug/1) + Bilberry (25 mg/1) + Biotin (280 ug/1) + Calcium carbonate (500 mg/1) + Cholecalciferol (300 [iU]/1) + Cyanocobalamin (125 mg/1) + Folic acid (1 mg/1) + Magnesium oxide (50 mg/1) + Pyridoxine hydrochloride (10 mg/1) Tablet, chewable Oral Avion Pharmaceuticals, Llc 2013-01-16 Not applicable US Ribotin-E Boron (25 ug/1) + Ascorbic acid (250 mg/1) + Biotin (100 ug/1) + Calcium carbonate (75 mg/1) + Cholecalciferol (13.75 ug/1) + Chromium nicotinate (37.5 ug/1) + Cupric oxide (1 mg/1) + Cyanocobalamin (13 ug/1) + DL-alpha tocopheryl acetate (45 mg/1) + Ferrous fumarate (9 mg/1) + Folic acid (500 ug/1) + Magnesium oxide (37.5 mg/1) + Manganese sulfate (0.75 mg/1) + Molybdenum (25 ug/1) + Nicotinamide (22.5 mg/1) + Pantothenic acid (15 mg/1) + Potassium Iodide (25 ug/1) + Potassium chloride (24.5 mg/1) + Pyridoxine hydrochloride (6 mg/1) + Riboflavin (3.35 mg/1) + Selenium (30 ug/1) + Thiamine mononitrate (3.25 mg/1) + Vitamin A acetate (1500 ug/1) + Zinc oxide (15 mg/1) Tablet Oral PureTek Corporation 2021-02-11 Not applicable US Zintrexyl-C Boron (25 ug/1) + Ascorbic acid (250 mg/1) + Biotin (100 ug/1) + Calcium carbonate (75 mg/1) + Cholecalciferol (13.75 ug/1) + Chromium nicotinate (37.5 ug/1) + Cupric oxide (1 mg/1) + Cyanocobalamin (13 ug/1) + DL-alpha tocopheryl acetate (45 mg/1) + Ferrous fumarate (9 mg/1) + Folic acid (500 ug/1) + Magnesium oxide (37.5 mg/1) + Manganese sulfate (0.75 mg/1) + Molybdenum (25 ug/1) + Nicotinamide (22.5 mg/1) + Pantothenic acid (15 mg/1) + Potassium Iodide (25 ug/1) + Potassium chloride (24.5 mg/1) + Pyridoxine hydrochloride (6 mg/1) + Riboflavin (3.35 mg/1) + Selenium (30 ug/1) + Thiamine mononitrate (3.25 mg/1) + Vitamin A acetate (1500 ug/1) + Zinc oxide (15 mg/1) Tablet Oral PureTek Corporation 2021-02-11 Not applicable US
Categories
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of inorganic compounds known as homogeneous metalloid compounds. These are inorganic compounds containing only metal atoms,with the largest atom being a metalloid atom.
- Kingdom
- Inorganic compounds
- Super Class
- Homogeneous metal compounds
- Class
- Homogeneous metalloid compounds
- Sub Class
- Not Available
- Direct Parent
- Homogeneous metalloid compounds
- Alternative Parents
- Not Available
- Substituents
- Homogeneous metalloid
- Molecular Framework
- Not Available
- External Descriptors
- boron group element atom, nonmetal atom (CHEBI:27560)
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- N9E3X5056Q
- CAS number
- 7440-42-8
- InChI Key
- ZOXJGFHDIHLPTG-UHFFFAOYSA-N
- InChI
- InChI=1S/B
- IUPAC Name
- boranylidyne
- SMILES
- [B]
References
- General References
- Not Available
- External Links
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 3 Completed Treatment Radiodermatitis 1 2 Recruiting Treatment Advanced Malignant Solid Neoplasm / Recurrent Malignant Solid Neoplasm 1 1 Terminated Treatment Brain and Central Nervous System Tumors 1 1 Unknown Status Treatment Diabetic Foot Ulcers (DFU) 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Tablet, film coated Oral Wafer Oral Tablet Oral Capsule Oral Tablet, chewable Oral - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source logP 0.33 ChemAxon Physiological Charge 0 ChemAxon Hydrogen Acceptor Count 0 ChemAxon Hydrogen Donor Count 0 ChemAxon Polar Surface Area 0 Å2 ChemAxon Rotatable Bond Count 0 ChemAxon Refractivity 0 m3·mol-1 ChemAxon Polarizability 1.78 Å3 ChemAxon Number of Rings 0 ChemAxon Bioavailability 1 ChemAxon Rule of Five Yes ChemAxon Ghose Filter No ChemAxon Veber's Rule Yes ChemAxon MDDR-like Rule No ChemAxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS Not Available
Drug created on December 03, 2015 16:51 / Updated on June 12, 2020 16:53