This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Summary
Copper gluconate is an ingredient found in a variety of supplements and vitamins.
- Generic Name
- Copper gluconate
- DrugBank Accession Number
- DB11246
- Background
Copper gluconate is a copper salt of D-gluconic acid that displays a light blue to bluish-green color. It is prepared by the reaction of gluconic acid solutions with cupric oxide or basic cupric carbonate. According to the good manufacturing or feeding practice by the FDA, copper gluconate is used as a nutrient or dietary supplement and is generally recognized as safe for use at a level not exceeding 0.005 percent.
- Type
- Small Molecule
- Groups
- Approved, Investigational
- Structure
Structure for Copper gluconate (DB11246)
- Weight
- Average: 453.841
Monoisotopic: 453.030556491 - Chemical Formula
- C12H22CuO14
- Synonyms
- Copper gluconate
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
- Associated Therapies
- Contraindications & Blackbox Warnings
Avoid life-threatening adverse drug eventsImprove clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events & improve clinical decision support.- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- No interactions found.
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Active Moieties
Name Kind UNII CAS InChI Key Copper unknown 789U1901C5 7440-50-8 RYGMFSIKBFXOCR-UHFFFAOYSA-N Cupric cation ionic 8CBV67279L 15158-11-9 JPVYNHNXODAKFH-UHFFFAOYSA-N - Over the Counter Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image Copper (gluconate) 2 Mg Tablets Tablet 2 mg Oral General Nutrition Canada Inc. 1997-04-18 2006-08-03 Canada 
- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image ADDEL JUNIOR Konzentrat zur Herstellung einer Infusionslösung Copper gluconate (142.8 μg/ml) + Manganese gluconate (4.052 μg/ml) + Potassium Iodide (1.308 μg/ml) + Sodium selenite (4.381 μg/ml) + Zinc gluconate (697 μg/ml) Injection, solution, concentrate Intravenous Laboratoire Aguettant 2017-05-17 Not applicable Austria 
ANTIOXIDANT FORMULA 45 FILM TABLET Copper gluconate (0.3 mg) + Ascorbic acid (333 mg) + Beta carotene (5000 IU) + Manganese gluconate (1 mg) + Selenium (0.033 mg) + Vitamin E (133 IU) + Zinc gluconate (5 mg) Tablet, film coated Oral FERROSAN SAĞLIK ÜRÜN VE HİZMETLERİ A.Ş. 2020-08-14 Not applicable Turkey 
C.A.G. Tab Copper gluconate (1 mg) + Ascorbic acid (250 mg) + Inositol (2.5 mg) + Pyridoxine hydrochloride (12.5 mg) + Riboflavin (12.5 mg) + Zinc oxide (25 mg) Tablet Oral Nutrition For Life International 1996-11-27 2000-08-11 Canada Children's Chew Multi & Min Tab Copper gluconate (1 mg / tab) + Ascorbic acid (30 mg / tab) + Beta carotene (1250 unit / tab) + Biotin (75 mcg / tab) + Calcium carbonate (100 mg / tab) + Choline bitartrate (5 mg / tab) + Cyanocobalamin (5 mcg / tab) + DL-alpha tocopheryl acetate (15 unit / tab) + Ferrous gluconate (2.5 mg / tab) + Iodine (.075 mg / tab) + Magnesium oxide (25 mg / tab) + Manganese gluconate (.5 mg / tab) + Nicotinamide (10 mg / tab) + Calcium pantothenate (6.25 mg / tab) + Potassium chloride (.5 mg / tab) + Potassium chloride (5 mg / tab) + Pyridoxine hydrochloride (1.25 mg / tab) + Riboflavin (1.25 mg / tab) + Thiamine hydrochloride (1.25 mg / tab) + Vitamin A palmitate (1250 unit / tab) + Vitamin D (200 unit / tab) + Zinc gluconate (1.25 mg / tab) Tablet Oral Natrol, Inc. 1995-12-31 2001-07-30 Canada Flexadyn Tab Copper gluconate (.1 mg / tab) + Cyanocobalamin (100 mcg / tab) + Magnesium carbonate (100 mg / tab) + Potassium gluconate (50 mg / tab) + Pyridoxine hydrochloride (50 mg / tab) + Vitamin A (1000 unit / tab) Tablet Oral Nutri Dyn Products Ltd. 1976-12-31 1996-09-09 Canada Iron, Vit & Min Supp Copper gluconate (1 mg / tab) + Choline bitartrate (82 mg / tab) + Cyanocobalamin (14 mcg / tab) + D-alpha-Tocopherol acetate (10 unit / tab) + Ferric ammonium citrate (30 mg / tab) + Folic acid (.1 mg / tab) + Niacin (2.5 mg / tab) + Nicotinamide (7.5 mg / tab) + Pantothenic acid (5 mg / tab) + Pyridoxine (1.5 mg / tab) + Riboflavin (1.2 mg / tab) + Thiamine (1 mg / tab) Tablet Oral Avacare, Division Of Jeunique International Inc. 1985-12-31 1996-09-09 Canada Men's Multi Master Formula Copper gluconate (1 mg) + Biotin (50 mcg) + Calcium ascorbate (200 mg) + Cholecalciferol (200 unit) + Choline bitartrate (25 mg) + Chromic chloride (19.5 mcg) + Cyanocobalamin (20 mcg) + Folic acid (0.20 mg) + Inositol (25 mg) + Iodine (0.15 mg) + Manganese gluconate (0.5 mg) + Nicotinamide (50 mg) + Calcium pantothenate (30 mg) + Potassium gluconate (1.6 mg) + Pyridoxine hydrochloride (30 mg) + Riboflavin (30 mg) + Sodium selenite (50 mcg) + Thiamine hydrochloride (30 mg) + Vitamin A palmitate (3500 unit) + Zinc gluconate (10 mg) + alpha-Tocopherol succinate (100 unit) Tablet Oral Pro Ma Systems 1998-10-31 2008-07-04 Canada Multi Vitamin-mineral Formula Copper gluconate (1 mg) + Ascorbic acid (50 mg / tab) + Calcium gluconate (35 mg / tab) + Choline bitartrate (125 mg) + Cyanocobalamin (5 mcg / tab) + Ferrous gluconate (7.5 mg) + Folic acid (0.025 mg / tab) + Inositol (62.5 mg) + Magnesium gluconate (12.5 mg) + Manganese gluconate (2.5 mg) + Niacin (17.5 mg / tab) + Calcium pantothenate (50 mg / tab) + Potassium Iodide (0.075 mg) + Riboflavin (0.6 mg / tab) + Thiamine hydrochloride (0.5 mg / tab) + Vitamin A (2500 unit / tab) + Vitamin D (100 unit / tab) + Zinc gluconate (12.5 mg) Tablet Oral Vita Health Products Inc 1997-04-03 1998-01-16 Canada Multivitamins and Minerals for Young Women Copper gluconate (0.5 mg / tab) + Ascorbic acid (37.5 mg / tab) + Beta carotene (2500 unit / tab) + Biotin (6.25 mcg / tab) + Calcium Phosphate (80 mg / tab) + Calcium Phosphate (62.5 mg / tab) + Cholecalciferol (100 unit / tab) + Choline bitartrate (6.25 mg / tab) + Cyanocobalamin (6.25 mcg / tab) + Ferrous fumarate (3.75 mg / tab) + Folic acid (0.2 mg / tab) + Inositol (6.25 mg / tab) + Magnesium oxide (25 mg / tab) + Manganese gluconate (0.5 mg / tab) + Niacin (6.25 mg / tab) + Calcium pantothenate (6.25 mg / tab) + Potassium Iodide (0.025 mg / tab) + Potassium gluconate (3.75 mg / tab) + Pyridoxine hydrochloride (5.25 mg / tab) + Racemethionine (6.25 mg / tab) + Riboflavin (6.25 mg / tab) + Thiamine hydrochloride (5 mg / tab) + Vitamin E (12.5 unit / tab) + Zinc citrate (2.5 mg / tab) Tablet Oral Quest Vitamins A Div Of Purity Life Health Products 2001-01-31 2004-06-29 Canada Nutryelt Konzentrat zur Herstellung einer Infusionslösung Copper gluconate (214.24 mg) + Chromic chloride (3.045 mg/l) + Ferrous gluconate (798.82 mg) + Manganese gluconate (44.569 mg) + Potassium Iodide (17.006 mg) + Sodium selenite (15.332 mg) + Sodium fluoride (209.95 mg) + Sodium molybdate dihydrate (4.293 mg) + Zinc gluconate (6970 mg) Injection, solution, concentrate Intravenous Laboratoire Aguettant 2016-02-09 Not applicable Austria - Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Prenatal Chelated Mineral Copper gluconate (0.5 mg/1) + Calcium carbonate (30 mg/1) + Calcium citrate tetrahydrate (32.5 mg/1) + Ferrous fumarate (7 mg/1) + Magnesium citrate (75 mg/1) + Potassium Iodide (75 ug/1) + Zinc citrate (5 mg/1) Tablet Oral Usana Health Sciences, Inc. 2012-04-11 2017-12-31 US 
Tricare Prenatal 2-part Daily Prenatal Vitamin System Copper gluconate (1 mg/1) + Ascorbic acid (30 mg/1) + Biotin (.150 mg/1) + Cholecalciferol (400 [iU]/1) + Chromium Cr-51 chloride (.060 mg/1) + Cyanocobalamin (.125 mg/1) + Doconexent (150 1/1) + Ferric pyrophosphate (4.5 mg/1) + Icosapent (37.5 1/1) + Levomefolic acid (1 mg/1) + Manganese citrate decahydrate (1 mg/1) + Nicotinamide (10 mg/1) + Omega-3 fatty acids (75 1/1) + Calcium pantothenate (5 mg/1) + Pyridoxine hydrochloride (2.5 mg/1) + Riboflavin (.85 mg/1) + Sodium selenite (.0325 mg/1) + Sodium molybdate (.0375 mg/1) + Thiamine mononitrate (1.25 mg/1) + Zinc (7 mg/1) + alpha-Tocopherol succinate (15 [iU]/1) Kit Oral Medecor Pharma, Llc 2016-05-10 Not applicable US Vista Advanced AREDS2 Formula Copper gluconate (1 mg/966.47mg) + Ascorbic acid (250 mg/966.47mg) + Glutathione (25 mg/966.47mg) + Lutein (5 mg/966.47mg) + Selenium (0.0275 mg/966.47mg) + Vitamin E (137.5 mg/966.47mg) + Zeaxanthin (1 mg/966.47mg) Capsule Oral Red Wedding LLC 2020-09-01 Not applicable US Vp-heme Ob Copper gluconate (0.8 mg/1) + Biotin (30 ug/1) + Cholecalciferol (400 [iU]/1) + Cyanocobalamin (12 ug/1) + Folic acid (1 mg/1) + Heme iron polypeptide (6 mg/1) + Iron sucrose (28 mg/1) + Nicotinamide (17 mg/1) + Calcium pantothenate (10 mg/1) + Potassium Iodide (250 ug/1) + Pyridoxine hydrochloride (50 mg/1) + Riboflavin (1.6 mg/1) + Sodium selenate (65 mg/1) + Thiamine mononitrate (1.5 mg/1) + Zinc oxide (4.5 mg/1) + alpha-Tocopherol succinate (10 [iU]/1) Tablet, film coated Oral Virtus Pharmaceuticals 2013-10-14 2016-05-31 US
Categories
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as sugar acids and derivatives. These are compounds containing a saccharide unit which bears a carboxylic acid group.
- Kingdom
- Organic compounds
- Super Class
- Organic oxygen compounds
- Class
- Organooxygen compounds
- Sub Class
- Carbohydrates and carbohydrate conjugates
- Direct Parent
- Sugar acids and derivatives
- Alternative Parents
- Medium-chain hydroxy acids and derivatives / Medium-chain fatty acids / Beta hydroxy acids and derivatives / Hydroxy fatty acids / Monosaccharides / Secondary alcohols / Carboxylic acid salts / Polyols / Carboxylic acids / Monocarboxylic acids and derivatives show 6 more
- Substituents
- Alcohol / Aliphatic acyclic compound / Beta-hydroxy acid / Carbonyl group / Carboxylic acid / Carboxylic acid derivative / Carboxylic acid salt / Fatty acid / Fatty acyl / Gluconic_acid show 15 more
- Molecular Framework
- Not Available
- External Descriptors
- organic molecular entity (CHEBI:31431)
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- RV823G6G67
- CAS number
- 527-09-3
- InChI Key
- OCUCCJIRFHNWBP-IYEMJOQQSA-L
- InChI
- InChI=1S/2C6H12O7.Cu/c2*7-1-2(8)3(9)4(10)5(11)6(12)13;/h2*2-5,7-11H,1H2,(H,12,13);/q;;+2/p-2/t2*2-,3-,4+,5-;/m11./s1
- IUPAC Name
- copper(2+) bis((2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate)
- SMILES
- [Cu++].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O
References
- General References
- Not Available
- External Links
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 2 Completed Treatment Pancreatic Metastatic Cancer 1 1 Completed Treatment Cancer 1 1 Recruiting Treatment Relapsed Sarcomas 1 1 Terminated Treatment Multiple Myeloma (MM) 1 1 Terminated Treatment Prostate Cancer 1 1, 2 Active Not Recruiting Treatment Glioblastoma Multiforme (GBM) 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Tablet Oral 2 mg Tablet, coated Oral Tablet Oral Tablet, effervescent Oral Solution, concentrate Intravenous Tablet, extended release Oral Injection, solution, concentrate Intravenous Kit Oral Tablet, chewable Oral Capsule Oral Tablet, film coated Oral - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 37.9 mg/mL ALOGPS logP -2 ALOGPS logP -3.4 Chemaxon logS -1.1 ALOGPS pKa (Strongest Acidic) 3.39 Chemaxon pKa (Strongest Basic) -3 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 7 Chemaxon Hydrogen Donor Count 5 Chemaxon Polar Surface Area 141.28 Å2 Chemaxon Rotatable Bond Count 10 Chemaxon Refractivity 49.11 m3·mol-1 Chemaxon Polarizability 16.62 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
Drug created at December 03, 2015 16:51 / Updated at February 21, 2021 18:53