Copper gluconate

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Copper gluconate is an ingredient found in a variety of supplements and vitamins.

Generic Name
Copper gluconate
DrugBank Accession Number
DB11246
Background

Copper gluconate is a copper salt of D-gluconic acid that displays a light blue to bluish-green color. It is prepared by the reaction of gluconic acid solutions with cupric oxide or basic cupric carbonate. According to the good manufacturing or feeding practice by the FDA, copper gluconate is used as a nutrient or dietary supplement and is generally recognized as safe for use at a level not exceeding 0.005 percent.

Type
Small Molecule
Groups
Approved, Investigational
Structure
Weight
Average: 453.841
Monoisotopic: 453.030556491
Chemical Formula
C12H22CuO14
Synonyms
  • Copper gluconate

Pharmacology

Indication

Not Available

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Associated Conditions
Indication TypeIndicationCombined Product DetailsApproval LevelAge GroupPatient CharacteristicsDose Form
Used in combination to treatTrace element deficiencyCombination Product in combination with: Zinc gluconate (DB11248), Selenious acid (DB11127), Potassium Iodide (DB06715), Manganese gluconate (DB11141)••••••••••••••••••••• ••••••• ••••••••• ••••••••• ••••••••••••••••• ••••••••• •••••••••••
Associated Therapies
Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
No interactions found.

Products

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Active Moieties
NameKindUNIICASInChI Key
Copperunknown789U1901C57440-50-8RYGMFSIKBFXOCR-UHFFFAOYSA-N
Cupric cationionic8CBV67279L15158-11-9JPVYNHNXODAKFH-UHFFFAOYSA-N
Over the Counter Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
Copper (gluconate) 2 Mg TabletsTablet2 mgOralGeneral Nutrition Canada Inc.1997-04-182006-08-03Canada flag
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
ADDEL JUNIOR Konzentrat zur Herstellung einer InfusionslösungCopper gluconate (142.8 μg/ml) + Manganese gluconate (4.052 μg/ml) + Potassium Iodide (1.308 μg/ml) + Sodium selenite (4.381 μg/ml) + Zinc gluconate (697 μg/ml)Injection, solution, concentrateIntravenousLaboratoire Aguettant2017-05-17Not applicableAustria flag
ANTIOXIDANT FORMULA 45 FILM TABLETCopper gluconate (0.3 mg) + Ascorbic acid (333 mg) + Beta carotene (5000 IU) + Manganese gluconate (1 mg) + Selenium (0.033 mg) + Vitamin E (133 IU) + Zinc gluconate (5 mg)Tablet, film coatedOralFERROSAN SAĞLIK ÜRÜN VE HİZMETLERİ A.Ş.1996-07-16Not applicableTurkey flag
C.A.G. TabCopper gluconate (1 mg) + Ascorbic acid (250 mg) + Inositol (2.5 mg) + Pyridoxine hydrochloride (12.5 mg) + Riboflavin (12.5 mg) + Zinc oxide (25 mg)TabletOralNutrition For Life International1996-11-272000-08-11Canada flag
Children's Chew Multi & Min TabCopper gluconate (1 mg / tab) + Ascorbic acid (30 mg / tab) + Beta carotene (1250 unit / tab) + Biotin (75 mcg / tab) + Calcium carbonate (100 mg / tab) + Choline bitartrate (5 mg / tab) + Cyanocobalamin (5 mcg / tab) + DL-alpha tocopheryl acetate (15 unit / tab) + Ferrous gluconate (2.5 mg / tab) + Iodine (.075 mg / tab) + Magnesium oxide (25 mg / tab) + Manganese gluconate (.5 mg / tab) + Nicotinamide (10 mg / tab) + Calcium pantothenate (6.25 mg / tab) + Potassium chloride (.5 mg / tab) + Potassium chloride (5 mg / tab) + Pyridoxine hydrochloride (1.25 mg / tab) + Riboflavin (1.25 mg / tab) + Thiamine hydrochloride (1.25 mg / tab) + Vitamin A palmitate (1250 unit / tab) + Vitamin D (200 unit / tab) + Zinc gluconate (1.25 mg / tab)TabletOralNatrol, Inc.1995-12-312001-07-30Canada flag
Flexadyn TabCopper gluconate (.1 mg / tab) + Cyanocobalamin (100 mcg / tab) + Magnesium carbonate (100 mg / tab) + Potassium gluconate (50 mg / tab) + Pyridoxine hydrochloride (50 mg / tab) + Vitamin A (1000 unit / tab)TabletOralNutri Dyn Products Ltd.1976-12-311996-09-09Canada flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Prenatal Chelated MineralCopper gluconate (0.5 mg/1) + Calcium carbonate (30 mg/1) + Calcium citrate tetrahydrate (32.5 mg/1) + Ferrous fumarate (7 mg/1) + Magnesium citrate (75 mg/1) + Potassium Iodide (75 ug/1) + Zinc citrate (5 mg/1)TabletOralUsana Health Sciences, Inc.2012-04-112017-12-31US flag
Tricare Prenatal 2-part Daily Prenatal Vitamin SystemCopper gluconate (1 mg/1) + Ascorbic acid (30 mg/1) + Biotin (.150 mg/1) + Cholecalciferol (400 [iU]/1) + Chromium Cr-51 chloride (.060 mg/1) + Cyanocobalamin (.125 mg/1) + Doconexent (150 1/1) + Ferric pyrophosphate (4.5 mg/1) + Icosapent (37.5 1/1) + Levomefolic acid (1 mg/1) + Manganese citrate decahydrate (1 mg/1) + Nicotinamide (10 mg/1) + Omega-3 fatty acids (75 1/1) + Calcium pantothenate (5 mg/1) + Pyridoxine hydrochloride (2.5 mg/1) + Riboflavin (.85 mg/1) + Sodium selenite (.0325 mg/1) + Sodium molybdate (.0375 mg/1) + Thiamine mononitrate (1.25 mg/1) + Zinc (7 mg/1) + alpha-Tocopherol succinate (15 [iU]/1)KitOralMedecor Pharma, Llc2016-05-10Not applicableUS flag
Vista Advanced AREDS2 FormulaCopper gluconate (1 mg/966.47mg) + Ascorbic acid (250 mg/966.47mg) + Glutathione (25 mg/966.47mg) + Lutein (5 mg/966.47mg) + Selenium (0.0275 mg/966.47mg) + Vitamin E (137.5 mg/966.47mg) + Zeaxanthin (1 mg/966.47mg)CapsuleOralRed Wedding LLC2020-09-01Not applicableUS flag
Vp-heme ObCopper gluconate (0.8 mg/1) + Biotin (30 ug/1) + Cholecalciferol (400 [iU]/1) + Cyanocobalamin (12 ug/1) + Folic acid (1 mg/1) + Heme iron polypeptide (6 mg/1) + Iron sucrose (28 mg/1) + Nicotinamide (17 mg/1) + Calcium pantothenate (10 mg/1) + Potassium Iodide (250 ug/1) + Pyridoxine hydrochloride (50 mg/1) + Riboflavin (1.6 mg/1) + Sodium selenate (65 mg/1) + Thiamine mononitrate (1.5 mg/1) + Zinc oxide (4.5 mg/1) + alpha-Tocopherol succinate (10 [iU]/1)Tablet, film coatedOralVirtus Pharmaceuticals2013-10-142016-05-31US flag

Categories

Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as sugar acids and derivatives. These are compounds containing a saccharide unit which bears a carboxylic acid group.
Kingdom
Organic compounds
Super Class
Organic oxygen compounds
Class
Organooxygen compounds
Sub Class
Carbohydrates and carbohydrate conjugates
Direct Parent
Sugar acids and derivatives
Alternative Parents
Medium-chain hydroxy acids and derivatives / Medium-chain fatty acids / Beta hydroxy acids and derivatives / Hydroxy fatty acids / Monosaccharides / Secondary alcohols / Carboxylic acid salts / Polyols / Carboxylic acids / Monocarboxylic acids and derivatives
show 6 more
Substituents
Alcohol / Aliphatic acyclic compound / Beta-hydroxy acid / Carbonyl group / Carboxylic acid / Carboxylic acid derivative / Carboxylic acid salt / Fatty acid / Fatty acyl / Gluconic_acid
show 15 more
Molecular Framework
Not Available
External Descriptors
organic molecular entity (CHEBI:31431)
Affected organisms
Not Available

Chemical Identifiers

UNII
RV823G6G67
CAS number
527-09-3
InChI Key
OCUCCJIRFHNWBP-IYEMJOQQSA-L
InChI
InChI=1S/2C6H12O7.Cu/c2*7-1-2(8)3(9)4(10)5(11)6(12)13;/h2*2-5,7-11H,1H2,(H,12,13);/q;;+2/p-2/t2*2-,3-,4+,5-;/m11./s1
IUPAC Name
copper(2+) bis((2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoate)
SMILES
[Cu++].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O

References

General References
Not Available
KEGG Compound
C12278
PubChem Compound
10692
PubChem Substance
347827950
ChemSpider
10242
RxNav
2839
ChEBI
31431
Wikipedia
Copper_gluconate

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
2TerminatedTreatmentPancreatic Metastatic Cancer1
1CompletedTreatmentCancer1
1RecruitingTreatmentRelapsed Sarcomas1
1TerminatedTreatmentMultiple Myeloma (MM)1
1TerminatedTreatmentProstate Cancer1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
TabletOral2 mg
Tablet, coatedOral
TabletOral
Tablet, effervescentOral
Solution, concentrateIntravenous
Tablet, extended releaseOral
Injection, solution, concentrateIntravenous
KitOral
Tablet, chewableOral
CapsuleOral
Tablet, film coatedOral
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility37.9 mg/mLALOGPS
logP-2ALOGPS
logP-3.4Chemaxon
logS-1.1ALOGPS
pKa (Strongest Acidic)3.39Chemaxon
pKa (Strongest Basic)-3Chemaxon
Physiological Charge-1Chemaxon
Hydrogen Acceptor Count7Chemaxon
Hydrogen Donor Count5Chemaxon
Polar Surface Area141.28 Å2Chemaxon
Rotatable Bond Count10Chemaxon
Refractivity49.11 m3·mol-1Chemaxon
Polarizability16.62 Å3Chemaxon
Number of Rings0Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available
Chromatographic Properties
Collision Cross Sections (CCS)
Not Available

Drug created at December 03, 2015 16:51 / Updated at May 19, 2024 10:11