Thioredoxin

DB11298ApprovedProtein Based Therapies

Thioredoxin is a small dithiol protein and specific reductant for major allergenic proteins present in foods from animal and plant products. It is a 12-kD oxidoreductase enzyme encoded by TXN... It is a 12-kD oxidoreductase enzyme encoded by TXN and TXN2 genes that contains a dithiol-disulfide active site.

Mechanism: Pharmacologically active on Mitogen-activated protein kinase kinase kinase 5
Curator reviewed

Resolves to

Compound

UNIIXJZ418133ZCAS52500-60-4

Clinical / RWD

RxNorm1314275

Targets

Q99683MAP3K5

What you can answer from here — as of July 07, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

4Marketed productsAcross 1 country and 2 labellers

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with Thioredoxin, and which of those have an active Phase 3 trial?

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