This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Kinetin
- DrugBank Accession Number
- DB11336
- Background
Kinetin is a cytokinin which are plant hormones promotes cell division and plant growth. It was shown to naturally exist in DNA of organisms including humans and various plants. While kinetin is used in tissue cultures to produce new plants, it is also found in cosmetic products as an anti-aging agents.
- Type
- Small Molecule
- Groups
- Approved
- Structure
Structure for Kinetin (DB11336)
- Weight
- Average: 215.2114
Monoisotopic: 215.080709935 - Chemical Formula
- C10H9N5O
- Synonyms
- Not Available
Pharmacology
- Indication
Not Available
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Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image ObagiGentle Rejuvenati Gentle Rejuvenation Kinetin (.03 mg/30g) + Zeatin (.03 mg/30g) Lotion Topical YS PLUS CORPORATION 2014-10-01 2015-12-31 US 
- Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image ObagiGentle Rejuvenati Gentle Rejuvenation Kinetin (.03 mg/30g) + Zeatin (.03 mg/30g) Lotion Topical YS PLUS CORPORATION 2014-10-01 2015-12-31 US
Categories
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as 6-alkylaminopurines. These are compounds that contain an alkylamine group attached at the 6-position of a purine. Purine is a bicyclic aromatic compound made up of a pyrimidine ring fused to an imidazole ring.
- Kingdom
- Organic compounds
- Super Class
- Organoheterocyclic compounds
- Class
- Imidazopyrimidines
- Sub Class
- Purines and purine derivatives
- Direct Parent
- 6-alkylaminopurines
- Alternative Parents
- Secondary alkylarylamines / Aminopyrimidines and derivatives / Imidolactams / Imidazoles / Heteroaromatic compounds / Furans / Oxacyclic compounds / Azacyclic compounds / Organopnictogen compounds / Organooxygen compounds show 1 more
- Substituents
- 6-alkylaminopurine / Amine / Aminopyrimidine / Aromatic heteropolycyclic compound / Azacycle / Azole / Furan / Heteroaromatic compound / Hydrocarbon derivative / Imidazole show 10 more
- Molecular Framework
- Aromatic heteropolycyclic compounds
- External Descriptors
- furans, 6-aminopurines (CHEBI:27407) / a small molecule (CPD-4609)
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- P39Y9652YJ
- CAS number
- 525-79-1
- InChI Key
- QANMHLXAZMSUEX-UHFFFAOYSA-N
- InChI
- InChI=1S/C10H9N5O/c1-2-7(16-3-1)4-11-9-8-10(13-5-12-8)15-6-14-9/h1-3,5-6H,4H2,(H2,11,12,13,14,15)
- IUPAC Name
- N-[(furan-2-yl)methyl]-7H-purin-6-amine
- SMILES
- C(NC1=NC=NC2=C1NC=N2)C1=CC=CO1
References
- General References
- Chiu PC, Chan CC, Lin HM, Chiu HC: The clinical anti-aging effects of topical kinetin and niacinamide in Asians: a randomized, double-blind, placebo-controlled, split-face comparative trial. J Cosmet Dermatol. 2007 Dec;6(4):243-9. [Article]
- External Links
- Human Metabolome Database
- HMDB0012245
- KEGG Compound
- C08272
- PubChem Compound
- 3830
- PubChem Substance
- 347827968
- ChemSpider
- 3698
- BindingDB
- 181147
- 16054
- ChEBI
- 27407
- ChEMBL
- CHEMBL228792
- ZINC
- ZINC000000001601
- PDBe Ligand
- H35
- Wikipedia
- Kinetin
- PDB Entries
- 2uy5 / 3o5w / 3t4s / 4a85 / 4a86 / 4jhh / 4jkx / 5rs8
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Lotion Topical - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.94 mg/mL ALOGPS logP 0.96 ALOGPS logP 0.51 Chemaxon logS -2.4 ALOGPS pKa (Strongest Acidic) 10.2 Chemaxon pKa (Strongest Basic) 3.43 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 4 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 79.63 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 60.72 m3·mol-1 Chemaxon Polarizability 21.33 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Drug created at December 03, 2015 16:52 / Updated at June 12, 2020 16:53