This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Lactobacillus plantarum
- DrugBank Accession Number
- DB11360
- Background
Lactobacillus plantarum is a member of Lactobacillus, or lactic acid bacteria, that it is widely used in the food industry as a microbial starter and probiotic microorganism. It is considered to be one of versatile species that carry out fermentative and metabolic processes, while exhibiting an antagonistic activity against pathogenic and spoilage microorganisms. L. plantarum produces different antimicrobial agents such as organic acids, hydrogen peroxide, diacetyl, bacteriocins, and antimicrobial peptides 1.
- Type
- Biotech
- Groups
- Investigational
- Synonyms
- Lactobacillus arabinosus whole
- Lactobacillus arizonensis whole
- Lactobacillus plantarum whole
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Maintenance of Gut health ••• ••• Used in combination to treat Infectious diarrhoea Combination Product in combination with: Zinc sulfate (DB09322), Bifidobacterium longum infantis (DB14222), MRx-4DP0004 (DB15751) •••••••••••• •••••••••• Adjunct therapy in treatment of Trichomonas vaginitis ••• ••• •••••••• ••••••• ••••••• •••••••• Adjunct therapy in treatment of Trichomonas vaginitis ••• ••• •••••••• ••••••• ••••••• •••••••• Treatment of Vaginal infections ••• ••• •••••••• ••••••• ••••••• •••••••• - Contraindications & Blackbox Warnings
Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- No interactions found.
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Over the Counter Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image Aldicom Liquid 1 g/100g Oral NAME 2019-10-09 Not applicable US 
Aldicom Liquid 30 g/100g Oral NAME 2019-10-09 Not applicable US Carecne Powder 51.9 g/100g Oral Biorhythm Co., Ltd 2018-05-23 Not applicable US Jangdaewon Probiotics Kids Powder 30 mg/2g Oral Daewon Pharmaceutical Co., Ltd. 2019-02-01 Not applicable US Kimchi Lactic Acid 1000 Granule 0.101 g/1.5g Oral Biogenicskorea Co., Ltd. 2015-10-14 Not applicable US - Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image BİOBER-ZN ORAL SÜSPANSİYON İÇEREN FLAKON, 5 ADET Lactobacillus plantarum (14.2 mg/10ml) + Bifidobacterium longum infantis (10 mg/10ml) + MRx-4DP0004 (6.6 mg/10ml) + Zinc sulfate heptahydrate (15 mg/10ml) Suspension Oral BERKO İLAÇ VE KİMYA SAN. A.Ş. 2017-09-26 Not applicable Turkey 
- Unapproved/Other Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Aldicom Lactobacillus plantarum (1 g/100g) Liquid Oral NAME 2019-10-09 Not applicable US Aldicom Lactobacillus plantarum (30 g/100g) Liquid Oral NAME 2019-10-09 Not applicable US Carecne Lactobacillus plantarum (51.9 g/100g) Powder Oral Biorhythm Co., Ltd 2018-05-23 Not applicable US Jangdaewon Probiotics Kids Lactobacillus plantarum (30 mg/2g) Powder Oral Daewon Pharmaceutical Co., Ltd. 2019-02-01 Not applicable US Kimchi Lactic Acid 1000 Lactobacillus plantarum (0.101 g/1.5g) Granule Oral Biogenicskorea Co., Ltd. 2015-10-14 Not applicable US
Categories
- Drug Categories
- Not Available
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- QFC21096ON
- CAS number
- Not Available
References
- General References
- Lobos O, Barrera A, Padilla C: Microorganisms of the Intestinal Microbiota of Oncorhynchus Mykiss Produce Antagonistic Substances Against Bacteria Contaminating Food and Causing Disease in Humans. Ital J Food Saf. 2017 Jun 27;6(2):6240. doi: 10.4081/ijfs.2017.6240. eCollection 2017 Apr 13. [Article]
- External Links
- PubChem Substance
- 347911199
- 1673942
- Wikipedia
- Lactobacillus_plantarum
Clinical Trials
- Clinical Trials
Phase Status Purpose Conditions Count 4 Completed Treatment Irritable Bowel Syndrome (IBS) 1 3 Active Not Recruiting Prevention Hematopoietic and Lymphoid System Neoplasm / Leukemias / Lymphoma 1 3 Completed Supportive Care Periodontal Disease 1 3 Recruiting Prevention Antibiotic Side Effect / Complications Implants / Implant Capsular Contracture / Implant Expulsion / Implant Infection / Implant site infection / Implant Site Pocket Infection 1 2 Completed Treatment Anxiety Disorders / Depression 1
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Liquid Oral 1 g/100g Liquid Oral 30 g/100g Capsule Oral Capsule Vaginal Douche Vaginal Suspension Oral Powder Oral 51.9 g/100g Powder Oral 30 mg/2g Granule Oral 0.101 g/1.5g Granule Oral 0.04 g/1.5g Granule Oral 0.08 g/1.5g Granule Oral 0.19 g/1.5g Capsule; insert Vaginal - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
Drug created at December 03, 2015 16:52 / Updated at February 13, 2021 10:52