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Iomeprol is a triiodinated nonionic radiographic contrast agent used for x-ray imaging and computed tomography (CT) scans. Iomeprol demonstrates low chemotoxicity, osmolality and viscosity and high water solubility.
- Mechanism
- Curator reviewed · 1 reference
Iomeprol is a radiographic iodinated contrast agent that opacifies the vessels and body structures where the contrast agent is present following intravenous or intra-arterial administration, permitting radiographic visualization of the internal structures through attenuation of X-ray photons. In imaging of the body, iodinated contrast agents diffuse from the vessels into the extravascular space. In normal brain with an intact blood-brain barrier, the contrast agent does not diffuse into the extravascular space and contrast enhancement is generally due to the presence of contrast within the vascular space. In patients with a disrupted blood-brain barrier, the contrast agent accumulates in the extravascular space in the region of disruption.
- Primary indication
- Intra-arterial iomeprol is indicated for: - Cerebral arteriography, including intra-arterial digital subtraction angiography (IA-DSA), in adults and pediatric patients - Visceral and peripheral arteriography and aortography, including IA-DSA, in adults and pediatric patients - Coronary...Curator reviewed · 26 structured indications
- Formula / weight
- C17H22I3N3O8 · 777.089 g/mol (avg)
- First approval
- United States, 2026
- Also known as
- 1,3-BENZENEDICARBOXAMIDE, N,N'-BIS(2,3-DIHYDROXYPROPYL)-5-((HYDROXYACETYL)METHYLAMINO)-2,4,6-TRIIODO- · N,N'-BIS(2,3-DIHYDROXYPROPYL)-2,4,6-TRIIODO-5-(N-METHYLGLYCOLAMIDO)ISOPHTHALAMIDE
- Code names
- E-7337
Resolves to
NJKDOADNQSYQEV-UHFFFAOYSA-NSMILESCN(C(=O)CO)C1=C(I)C(C(=O)NCC(O)CO)=C(I)C(C(=O)NCC(O)CO)=C1IWhat you can answer from here — as of September 16, 2026
Which drugs share a target with Iomeprol, and which of those have an active Phase 3 trial?